Clinical trials: Breastcancer
Metastatic Breast Cancer, Metastatic Breast Cancer (MBC)
Fit2ThriveMB: Optimization of a Physical Activity Promotion Intervention for Metastatic Breast Cancer Patients
The purpose of this study is to examine which of four components of a digital health intervention using an App and Fitbit meaningfully contribute to increased physical activity in Metastatic Breast Cancer Patients.
- Conditions
- Metastatic Breast Cancer, Metastatic Breast Cancer (MBC), Metastatic Breastcancer
- Trial name
- Fit2ThriveMB (NCT07840599)
- Testing
- Core Intervention, EHR Integration (On v. Off), Weekly Coaching
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Northwestern University
Breastcancer, Mastectomy
Study Evaluating the Efficacy of Loco-regional Anaesthesia PECS on Chronic Pain of a Mastectomy
A non-randomized, mono-centric, prospective interventional study that will assess the efficacy of the loco-regional anesthesia PECS on the rate of chronic pain, 6 month after a patient will have either received a mastectomy or a…
- Trial name
- PECS (NCT03023007)
- Testing
- Loco-regional anaesthesia
- Where
- France
- Volunteers
- 194 people
- Sponsor
- Centre Oscar Lambret
Metastatic Breastcancer
Schedules of Nab-Paclitaxel in Metastatic Breast Cancer
Longer first line chemotherapy duration has recently been associated with a modest, but significant improvement in overall survival and a clinically meaningful and statistically significant improvement in progression-free…
- Trial name
- SNAP (NCT01746225)
- Testing
- nab-Paclitaxel
- Where
- 41 sites in Belgium, Ireland and 4 more
- Volunteers
- 258 people
- Sponsor
- ETOP IBCSG Partners Foundation
Breastcancer
Trial Evaluating Role of Post Mastectomy Radiotherapy in Women With Node Negative Early Breast Cancer
Postmastectomy radiotherapy (PMRT) is unequivocally beneficial in reducing the recurrences as well as improving survival in node positive breast cancer patients.
- Trial name
- PMRT-NNBC (NCT02992574)
- Testing
- Post Mastectomy Radiation therapy
- Where
- 7 sites in India
- Volunteers
- 1,022 people
- Sponsor
- Tata Memorial Centre
Breastcancer
A Clinical Study to Determine the Pharmacokinetics of Oraxol in Breast Cancer Patients
This is a multicenter, open-label, single-arm PK study in patients for whom paclitaxel treatment is indicated.
- Trial name
- NCT03165955
- Testing
- Oraxol
- Where
- 6 sites in Taiwan
- Volunteers
- 28 people
- Sponsor
- Health Hope Pharma
Breastcancer, Perioperative Pain
Efficacy of Serratus Posterior Intercostal Plane Block for Analgesia and Inflammatory Marker in Breast Surgery
To study the efficiacy of serratus posterior superior block in controlling perioperative breast cancer surgery pain and its effect on inflamatory markers.
- Conditions
- Breastcancer, Perioperative Pain, Inflammation
- Trial name
- NCT06502067
- Testing
- Analgesia mangement group A,B
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Breastcancer
Outcome of 15 Versus 5 Fractions in Adjuvant Breast Radiotherapy in Women Over 65 Years
This study will evaluate the effect of highly accelerated external beam radiotherapy (EBRT) in 5 fractions over 10 days compared to 15 fractions over 3 weeks for early as well as locally-advanced stage breast cancer.
- Trial name
- HAI-5-III (NCT03121248)
- Testing
- WBI 5 fractions, WBI 15 fractions, LNI 5 fractions
- Where
- Belgium
- Volunteers
- 144 people
- Sponsor
- University Hospital, Ghent
Breastcancer
An Extension Study to Provide Oraxol to Patients Who Completed KX-ORAX-007
KX-ORAX-008 is an extension study of patients who completed KX-ORAX-007 without disease progression as defined by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 and who wish to continue Oraxol treatment.
- Trial name
- NCT04168957
- Testing
- Oraxol
- Where
- 5 sites in Taiwan
- Volunteers
- 11 people
- Sponsor
- Athenex, Inc.
Breastcancer, Breast Diseases
Empowering Latinas to Obtain Breast Cancer Screenings
The participatory-based project will quantify the 'added benefit' of an empowerment intervention relative to an education intervention for 150 Latinas on the following outcomes: women's adherence to breast cancer screening…
- Trial name
- NCT02964234
- Testing
- Empowerment, Education
- Where
- 3 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Breastcancer
A PK Study of Oraxol in Breast Cancer Patients
This is a multicenter, open-label, single-arm PK study in approximately 24 breast cancer patients for whom paclitaxel treatment is indicated.
- Trial name
- NCT04993040
- Testing
- Oraxol
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Athenex, Inc.
Breastcancer
Breast, Omega 3 Free Fatty Acid, Ph 0
Assess the impact of dietary omega 3 free fatty acids breast cancer patients.
- Trial name
- NCT02996240
- Testing
- Omega-3 FFA
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Breastcancer, Breast Neoplasm
SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer
This is a single arm, open label study of SV-BR-1-GM, a targeted immunotherapy for breast cancer. Eligible patients will have histological confirmation of breast cancer with recurrent and/or metastatic lesions.
- Trial name
- NCT03066947
- Testing
- SV-BR-1-GM, Cyclophosphamide, Interferon-alpha-2b
- Where
- 5 sites in United States
- Volunteers
- 24 people
- Sponsor
- BriaCell Therapeutics Corporation
Breastcancer, Phyllodes Breast Tumor
Establishing Technique for PECS2 Catheter Insertion
The investigators are trying to establish an easy technique for insertion of a catheter for continuous infusion while performing pectoral type 2 (serratus) block, as a post operative pain controlling measure for cases undergoing…
- Trial name
- ETCI (NCT03030677)
- Testing
- Pectoralis II block & catheter without Lidocaine dissection, Pectoralis II block & catheter with Lidocaine dissection, catheter insertion
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Kasr El Aini Hospital
Breastcancer
Minimal Invasive Breast Cancer Excision Using the Breast Lesion Excision System Under Ultrasound Guidance
This study will assess whether it is feasible to remove small breast cancers completely using the Breast Lesion Excision System under Ultrasound guidance.
- Trial name
- BLES (NCT02975128)
- Testing
- BLES system and conventional lumpectomy
- Where
- 2 sites in Netherlands
- Volunteers
- 22 people
- Sponsor
- Radboud University Medical Center
Breastcancer, Emotional Disorder
Presential Vs Online Group-based Psychosocial Treatment for Breast Cancer Survivors.
This multicenter study is a sequential RCT which aims to prove, in the first stage, the efficacy of a face-to-face Positive Psychotherapy in Cancer (PPC) group compared to a Cognitive Behavioral Stress Management (CBSM) group.
- Conditions
- Breastcancer, Emotional Disorder, Distress
- Trial name
- PSONLINE (NCT03010371)
- Testing
- Positive Psychotherapy, Positive Online Psychotherapy, Cognitive Behavioral Therapy
- Where
- Spain
- Volunteers
- 365 people
- Sponsor
- Institut Català d'Oncologia
Metastatic Breastcancer
Magnetic Resonance Imaging of the Whole Body, Including Diffusion, in the Medical Evaluation of Breast Cancers at High Risk for Metastasis and the Follow-up of Metastatic Cancers
Whole-body MRI including diffusion is a booming technique. Numerous studies have demonstrated its interest in metastatic cancers.
- Trial name
- NCT02966574
- Testing
- whole body MRI
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Brugmann University Hospital
Diffuse Large B-cell Lymphoma, Hodgkin Lymphoma
BMS_PD-L1_onco : Assessment of the PD-L1 Protein as a Biomarker in Oncology and Hematology
Diffuse large B-cell lymphomas (DLBCLs) represent 25 to 30% of adult non-Hodgkin lymphomas in western countries. DLBCLs are aggressive cancer but potentially curable with multi-agent chemotherapy.
- Conditions
- Diffuse Large B-cell Lymphoma, Hodgkin Lymphoma, Metastatic Breastcancer, Non-small Cell Lung Cancer
- Trial name
- BMS_PD-L1 (NCT01660776)
- Where
- 4 sites in France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Lymph Node, Breastcancer
CK19 Combined With Contrast-enhanced Ultrasound: a Prediction System on Axillary Lymph Node Metastasis in Breast Cancer
To establish a predicting system on axillary lymph node metastasis based on peripheral blood CK19mRNA and contrast-enhanced ultrasound.
- Trial name
- CK-CEUS (NCT02992067)
- Where
- China
- Volunteers
- 359 people
- Sponsor
- Zhejiang Cancer Hospital
Breastcancer
The Efficacy and Safety of PEG-rhG-CSF（Pegylated Recombinant Human Granulocyte Colony Stimulating Factor)in Patients With Breast Cancer Who Were Treated With Intensive Chemotherapy
The purpose of the study is to evaluate the efficacy and safety of PEG-rhG-CSF in patients with breast cancer who were treated with intensive chemotherapy for prevention of neutrophil reduction.
- Trial name
- NCT02944604
- Testing
- PEG-rhG-CSF
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University
Metastatic Breastcancer
Advanced Breast Cancer and Lifestyle Exercise Study
About 5% of breast cancers are metastatic at diagnosis and 20-30% of localized breast cancer become secondarily metastatic.Thanks to recent therapeutic advances, the median survival ranges between 12 months in 1970 and 18 to 24…
- Trial name
- ABLE (NCT03148886)
- Testing
- PA intervention
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Leon Berard