Clinical trials: Breast Cancer Female NOS
Breast Cancer Female, Breast Cancer
Omission of SLNB in Triple-negative and HER2-positive Breast Cancer Patients With rCR and pCR in the Breast After NAST
Currently, axillary surgery for breast cancer is considered as staging procedure that does not seem to influence breast cancer mortality, since the risk of developing metastasis depends mainly on the biological behaviour of the…
- Trial name
- NCT04101851
- Testing
- omission of SLNB
- Where
- 40 sites in Austria, Germany and 2 more
- Volunteers
- 350 people
- Sponsor
- Toralf Reimer, MD PhD
Breast Cancer Female, Leptomeningeal Metastases
BATs in Patients With Breast Cancer and Leptomeningeal Metastases
This study uses bi-specific antibody (HER2Bi) armed activated T-cells (HER2 BATs) to target breast cancer cells that have metastasized to the membranes surrounding the brain and spinal cord.
- Trial name
- NCT03661424
- Testing
- HER2 BATs
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Virginia
Breast Cancer Female, Infertility, Female
Impact of Breast Cancer on Human Folliculogenesis
Advances in cancer diagnosis and treatments have improved the 5-year survival rate for patients over the last decade. Nevertheless, cancer treatments frequently alter patient's fertility, thus compromising their ability to…
- Trial name
- FERTICAN (NCT07148141)
- Testing
- Ovarian stimulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Breast Cancer Female
Pain and Functional Recovery After Mastectomy and IBR by Implant: Prepectoral Versus Subpectoral Technique
This is a prospective, single-center, non-randomized study of immediate breast reconstruction (IBR) using a pre- or retro-pectoral technique in patients with breast cancer who have undergone total mastectomy.
- Trial name
- DREAM-RMI (NCT05527769)
- Testing
- mastectomy + immediate breast reconstruction
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer Female
Adjuvant Therapy With Abemaciclib + SOC ET vs. SOC ET in Clinical or Genomic High Risk, HR+/HER2- EBC
Patients with breast cancer, who have completed first line therapy (e.g., radiotherapy, chemotherapy, surgery), and who have to be identified with having a high risk of recurrence of cancer, will be eligible for the study.
- Trial name
- ADAPTlate (NCT04565054)
- Testing
- Abemaciclib 50 MG; 150mg 1-0-1 per os
- Where
- 85 sites in Germany, Poland and 1 more
- Volunteers
- 1,260 people
- Sponsor
- Women's Cancer Study Group GmbH
Breast Neoplasms, Breast Cancer Detection
Diagnostic Accuracy of Carebot AI MMG in Mammography Screening: Multicenter MRMC Study
This study evaluates the diagnostic performance of Carebot AI MMG, an artificial intelligence (AI)-enabled medical device for evaluating mammograms.
- Conditions
- Breast Neoplasms, Breast Cancer Detection, Breast Cancer - Female, Breast Cancer Screening
- Trial name
- CARE-MMG-MRMC (NCT07298252)
- Testing
- Carebot AI MMG software analysis
- Where
- 4 sites in Czechia, Slovakia
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- Carebot s.r.o.
Breast Cancer Female, Mastectomy
Opting for Breast Reconstruction After Mastectomy or Not: Search for Influencing Factors
The purpose of this study is to investigate the factors influencing the decision about breast reconstruction after breast amputation for breast cancer.
- Conditions
- Breast Cancer Female, Mastectomy, Breast Reconstruction
- Trial name
- NCT03039348
- Testing
- semi-structured interview using a questionnaire
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Symptom Distress During Breast Cancer Treatment
Trajectory Analysis of Symptom Distress and Cancer-related Fatigue After Adjuvant Chemotherapy in Breast Cancer Female
When receiving adjuvant chemotherapy, a variety of symptoms will appear and it is very painful. These symptoms occur at the same time and are related to each other.
- Trial name
- NCT04911699
- Testing
- breast adenocarcinoma receiving chemotherapy, Control-for
- Volunteers
- 120 people
- Sponsor
- Taipei Medical University
Breast Cancer Female, Breast Neoplasm
HORIZONS: Understanding the Impact of Cancer Diagnosis and Treatment on Everyday Life
The purpose of this study is to invite all people diagnosed with cancer who meet the eligibility criteria to complete questionnaires before their treatment begins and at regular intervals over time to assess the impact of cancer…
- Conditions
- Breast Cancer Female, Breast Neoplasm, Non-Hodgkin's B-cell Lymphoma, Non-Hodgkin's Lymphoma, Adult High Grade
- Trial name
- NCT03000192
- Where
- 111 sites in United Kingdom
- Volunteers
- 3,000 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Breast Cancer Female
Vascular Supply Identification, Lesion Extension and Search for Tumor Similarity at a Distance by VTM in Breast Cancer
When we talk about early identification, we are talking about an ALREADY EXISTING INJURY, triggering a change in the patient's quality of life and a projection of future costs for the health system.
- Trial name
- NCT06045572
- Testing
- VTM examination and breast biopsy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Galzu Institute of Research, Teaching, Science and Applied Technology
Breast Cancer Female, Gynecologic Cancer
Transcranial Magnetic Stimulation for Chemotherapy-Induced Peripheral Neuropathy in Breast and Gynecologic Cancer Survivors
The goal of this study is to evaluate the change in pain scores among patients with chemotherapy-induced peripheral neuropathy after receiving treatment with repetitive transcranial magnetic stimulation (rTMS).
- Trial name
- rTMS for CIPN (NCT07120100)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Utah
Breast Cancer Female
DEPO-Trigger Trial: GnRH Agonist DEPOt TRIGGER for Final Oocyte Maturation
For breast cancer patients who are candidates to receive chemotherapy, concurrent use of temporary ovarian suppression with gonadotropin-releasing hormone agonists (GnRHa) can be offered as ovarian protection.
- Trial name
- Depo-Trigger (NCT04616729)
- Testing
- Triptorelin 3.75 MG Injection, Transvaginal oocyte retrieval, Triptorelin Injection
- Where
- 2 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Universitair Ziekenhuis Brussel
Breast Cancer Female
The Anti-tumor Effect of Metformin And Atorvastatin in Breast Cancer
This study aims at evaluating and comparing the anti-tumor effects of metformin and statins (hydroxyl-methyl-glutaryl-CoA reductase inhibitors) in patients with non-metastatic breast cancer (stage I, II, \& III).
- Trial name
- NCT05507398
- Volunteers
- 100 people
- Sponsor
- Tanta University
Breast Cancer, Breast Cancer Female
Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer
This study involves a course of radiation to the tumor that is delivered BEFORE surgery. The type of radiation is called stereotactic ablative body radiation therapy (SABR).
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Adenocarcinoma
- Trial name
- NCT03137693
- Testing
- Standard of Care Schedule Variation: SABR, Breast-conserving Surgery
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Breast Cancer Female
21DIF039: Prone to Supine Breast MRI II, P2S2 Breast MRI Trial
The purpose of this study is to determine whether a supine breast MRI obtained with a second intravenous injection of gadolinium contrast immediately after a standard clinical prone breast MRI will provide sufficient tumor…
- Trial name
- 21DIF039 (NCT05131607)
- Testing
- Supine MRI
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Cancer, Stage III Breast Cancer
TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients
This research is being done to assess whether an exercise intervention with protein intake support vs a health education and support program will make it easier for women age 65 or older who are receiving chemotherapy for breast…
- Conditions
- Breast Cancer, Stage III Breast Cancer, Breast Cancer Female, Stage I Breast Cancer
- Trial name
- THRIVE-65 (NCT05535192)
- Testing
- THRIVE, Health Education Support Program
- Where
- 4 sites in United States
- Volunteers
- 270 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer Female
Comparison of Changes in the Quality of Life of Patients Operated on Breast Cancer at the Drôme Ardèche Breast Institute According to Access to Supportive Oncological Care (IDSein)
The aim of this study is to explore the quality of life of cancer patients, in particular women operated on breast cancer, throughout their care journey, taking into account their access to supportive oncological care within and…
- Trial name
- IDSein (NCT05116449)
- Testing
- Quality of life questionnaires
- Where
- 2 sites in France
- Volunteers
- 310 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Breast Cancer Female
Effect of Heavy-load Resistance Training During Chemotherapy on Muscle Cellular Outcomes
(Neo-)adjuvant chemotherapy for breast cancer is known to have a negative impact on muscle tissue resulting in reduced aerobic fitness, skeletal muscle mass and strength.
- Trial name
- NCT04586517
- Testing
- Heavy-load resistance training, Control
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Uppsala University
Breast Cancer Female
Factors Influencing Tamoxifen Adherence in Women With Breast Cancer Receiving Tamoxifen in Botswana.
Botswana is an ideal location to investigate tamoxifen adherence for numerous reasons. First, in contrast to many other countries in SSA, tamoxifen is affordable and widely available to women with ER+ breast cancer in Botswana.
- Trial name
- TAM (NCT06660030)
- Testing
- No intervention
- Where
- Botswana
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Patient Reported Outcome, Oncological Safety
Patient Report Outcome and Oncological Safety -Oncoplastic and Conventional BCS Cohort
Breast-conserving surgery (BCS) is the traditional surgical treatment for early-stage breast cancer patients. There are evidences indicating that oncoplastic BCS could improve cosmetic outcomes and/or quality of life, and has…
- Conditions
- Patient Reported Outcome, Oncological Safety, Breast-conserving Surgery, Breast Cancer Female
- Trial name
- NCT05054777
- Testing
- oncoplastic breast-conserving surgery, conventional breast-conserving surgery
- Volunteers
- 5,000 people
- Sponsor
- Shandong Cancer Hospital and Institute