Clinical trials: Brain Structure
Brain Structure, Cognitive Performance
Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis
This study investigates the effects of extended-duration spaceflight (12-month International Space Station missions) on general cognitive performance (measured with the Cognition test battery), spatial cognition, structural and…
- Trial name
- NCT04856410
- Testing
- Spaceflight, Controls
- Where
- 3 sites in United States, Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cognition, Brain Health
Brain Response to an Intervention Using Guided, At-Home Technology for the Mind
The objective of this study is to assess the effectiveness of two digital programs for providing mental stimulation, improving cognition, and inducing changes in brain structure and function.
- Conditions
- Cognition, Brain Health, Brain Structure, Brain Function
- Trial name
- BRIGHT-Mind (NCT05912556)
- Testing
- Digital Program 1, Digital Program 2
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Lumos Labs, Inc.
Type2 Diabetes, Type 2 Diabetes Mellitus in Obese
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications
- Trial name
- Metabrain (NCT05277558)
- Testing
- Observational
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Falling, Community Dwelling Older Adults
Neurophysiological Changes After Perturbation-based Training in Older Adults
This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group.
- Conditions
- Falling, Community Dwelling Older Adults, Postural Stability, Brain Connectivity
- Trial name
- NCT06573658
- Testing
- Perturbation-based balance training (PBT), Walking exercise (control)
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cognitive Performance, Brain Structure
Rhythm Experience and Africana Culture Trial
REACT is a randomized intervention to examine the benefits of African Dance as a method to increase physical activity behaviors in older adults.
- Trial name
- REACT (NCT03771716)
- Testing
- African Dance, African Cultural Immersion
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Transcranial Direct Current Stimulation, Ankle
Investigating the Effects of Transcranial Direct Current Stimulation to Different Brain Regions on Ankle Tracking Motor Learning, Motor Adaptation, and Brain Connectivity in Healthy Middle-aged and Older Adults and Patients With Subcortical Stroke
Ankle control is essential to safe over-ground navigation for humans. Middle- aged and older adults and patients with stroke whose ankle control is poor often lose their balance or fall.
- Conditions
- Transcranial Direct Current Stimulation, Ankle, Motor Learning, Adaptation
- Trial name
- tDCS (NCT06556043)
- Testing
- cM1 transcranial direct current stimulation, cPPC transcranial direct current stimulation, iCBM transcranial direct current stimulation
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital