Clinical trials: Brain Injury, Chronic
Concussion, Mild
The Combined Effect of Chronic Cannabis Use and Subconcussive Head Impacts on Brain Health
The purpose of this pilot study is to better understand the effects of chronic cannabis (THC) use on the neural responses to subconcussive head impacts, as a form of repetitive soccer headings.
- Trial name
- NCT04641832
- Testing
- Soccer heading
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Indiana University
Cerebral Palsy (CP), Spastic Paraplegia
Retrospective Study on the WalkOn AFO in Children or Teenagers With Neurological Pathologies
The goal of this observational study is to assess the interest of prefabricated carbon fiber ankle foot orthoses (AFO) in children and teenagers with central or peripheral neurological pathologies.
- Conditions
- Cerebral Palsy (CP), Spastic Paraplegia, Spinal Cord Injuries (SCI), Spina Bifida
- Trial name
- NCT06740006
- Where
- France
- Volunteers
- 65 people
- Sponsor
- Otto Bock France SNC
Cerebral Palsy
The Follow Study of Speech Functions in Preschool Children With Cerebral Palsy: Clinical Measures and Acoustic Analysis
The aims of this study: 1. to investigate the difference in motor speech functions among children with cerebral palsy (CP) of different motor severities. 2.
- Trial name
- NCT02378987
- Where
- Taiwan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cerebral Palsy Infantile
Study of Sagittal Pelvic Statics in the Sitting Position in Children With Cerebral Palsy
Cerebral palsy is the leading cause of motor disability in children. Children with little or no walking (GMFCS III, IV and V) represent 43% of children with cerebral palsy, the majority of whom present pelvic and spinal…
- Trial name
- SPS-PC (NCT05657548)
- Testing
- spine and pelvis radiography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Mild to Moderate Traumatic Brain Injury
PoNS Clinical Experience Program (TBI)
Brief Summary: Prospective, cohort, open-label study. The cohort consists of people who have a chronic balance dysfunction due to a mild to moderate traumatic brain injury (TBI).
- Trial name
- NCT03732755
- Testing
- PoNS Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Helius Medical Inc
Musculoskeletal Disorder, Rotator Cuff Tendinitis
Body Schema Alterations in Musculoskeletal Disorders : Effect of Laterality
This study assess ocular movements in a hand laterality judgment task in a population of musculoskeletal disorders. Reaction time, error rate and visual strategy are compared between musculoskeletal disorders and healthy…
- Conditions
- Musculoskeletal Disorder, Rotator Cuff Tendinitis, Chronic Low Back Pain, Carpal Tunnel Syndrome
- Trial name
- Schem-TMS (NCT03567109)
- Testing
- hand laterality judgment task
- Where
- France
- Volunteers
- 71 people
- Sponsor
- University Hospital, Angers
Cerebral Palsy, Pes Planus
The Effect of Kinesio Taping on q Angle and Pes Planus in Children With Cerebral Palsy
The aim of our study is to examine the effect of using kinesiology tape and using it for 8 weeks on Q angle and pes planus on children with cerebral palsy.
- Trial name
- NCT06004271
- Testing
- exercise, exercise and taping
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Uskudar University
Cerebral Palsy
The Effects of Protocolized Breathing Exercises on Pulmonary Function in Adolescents With Cerebral Palsy.
This multicenter randomized controlled pilot trial evaluates whether an 8-week protocolized breathing exercise program improves pulmonary function and quality of life in adolescents and young adults with cerebral palsy.
- Trial name
- NCT07873593
- Testing
- Protocolized breathing exercises
- Where
- Hungary
- Volunteers
- 360 people
- Sponsor
- Semmelweis University
Cerebral Palsy
Urdu Version of Pediatric Balance Scale
Children with cerebral palsy often suffer from a lack of balance compared with typically developing children. Because balance capacity is relevant to functional activities, reliable and valid functional balance measures are…
- Trial name
- NCT04768049
- Testing
- Tool Translation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Stroke, Dystonia
MyoSense- Automated Muscle Hypertonicity Classification System
It is often difficult to quantify and distinguish aspects of abnormal muscle tone due to neurological injury. This makes it difficult to evaluate therapies that aim to reduce the effects of abnormal muscle tone.
- Conditions
- Stroke, Dystonia, Cerebral Palsy
- Trial name
- NCT02076581
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Great Lakes NeuroTechnologies Inc.
Cerebral Palsy
Effects of Walking Analysis on Surgical Outcomes
The purpose of this study is to evaluate the effects of pre-operative gait analysis testing on surgical outcomes in children with cerebral palsy who have problems walking.
- Trial name
- NCT00114075
- Testing
- Surgery with gait analysis report, Surgery without gait analysis report
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Pediatric Hemiparesis
Brain Stimulation and Hand Training in Children With Hemiparesis
Hemiparetic cerebral palsy influences motor function in children during development and throughout their lifetime. The deficits one sees are the result both of the congenitally induced brain lesion and the subsequent plasticity…
- Trial name
- NCT02250092
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Hemiplegia, Cerebral Palsy
Infant Modified Constraint Induced Movement Therapy Paired With Neuromuscular Electrical Stimulation: a Case Series
This study will compare the motor outcomes for five infants with asymmetrical hand function (AHF) who will receive two, three week episodes of standard care separated by a three week episode of mCIMT paired with Neuromuscular…
- Conditions
- Hemiplegia, Cerebral Palsy, Unilateral Cerebral Palsy
- Trial name
- NCT05134272
- Testing
- Neuromuscular electrical stimulation, Modified constraint induced movement therapy, Standard care for infant with asymmetrical hand function
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Kathy Grinde
Posttraumatic Stress Disorder
Use of Repetitive Transcranial Magnetic Stimulation (rTMS) in Chronic Posttraumatic Stress Disorder (PTSD)
Posttraumatic stress disorder occurs in patients who have experienced, witnessed or have been confronted with an event involving actual death or the threat of death, serious injury, or the threat to physical health and felt fear…
- Trial name
- NCT00001657
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Mental Health (NIMH)
Traumatic Brain Injury
Autologous Adipose-Derived Mesenchymal Stem Cells for Chronic Traumatic Brain Injury
The global objective of this study is to establish the safety and investigate the potential treatment effect of an intravenous infusion of HB-adMSCs (Hope Biosciences adipose-derived mesenchymal stem cells) on brain structure…
- Trial name
- NCT05951777
- Testing
- Autologous HB-adMSCs, Normal Saline
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Hope Biosciences LLC
Cerebral Palsy, Hemiplegic Cerebral Palsy
Implementation of Therapy Together
The goal of this clinical trial is to learn about the implementation of Therapy Together, a pediatric constraint-induced movement therapy program in young children with unilateral cerebral palsy.
- Trial name
- NCT06040619
- Testing
- Therapy Together, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Texas Scottish Rite Hospital for Children
Cerebral Palsy, Iron Deficiency Anemia
Comparison of Twice Weekly Versus Daily Iron Therapy in Treating Anemia in Children With Cerebral Palsy
a randomized clinical trial to compare the effect of twice weekly versus daily iron therapy in treating anemia in children with cerebral palsy, to be conducted at Department of pediatric medicine children's hospital PIMS…
- Trial name
- NCT06176430
- Testing
- Ferrous Sulfate Oral Product
- Volunteers
- 160 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Cerebral Palsy
Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Evidence from literature support the use of Botulinum toxin A (BoNT-A) for upper limb spasticity management in children with cerebral palsy (CP).
- Trial name
- NCT03302871
- Testing
- Botulinum toxin type A, transcranial direct current stimulation, hybrid training model of CIMT and BIT
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
Neuromuscular Diseases, Cerebral Palsy
Rehabilitative Effect of the Use of a Gait Exoskeleton in Patients With Neuromuscular Disease or Cerebral Palsy
The purpose of this multicentric study is to assess the rehabilitative effect derived from the use of the ATLAS exoskeleton in children with neuromuscular diseases or cerebral palsy and with a level of less than 3 or less in the…
- Conditions
- Neuromuscular Diseases, Cerebral Palsy, SMA II
- Trial name
- NCT04813601
- Testing
- ATLAS 2030
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- MarsiBionics
DNS, Cerebral Palsy
Effects of Reflex Mediated Core Stability Exercise on Sensory Processing Skills and Gross Motor Function
Current literature on DNS in CP primarily focuses on motor outcomes like postural control and balance. Therefore, there are fewer studies up to researcher's knowledge about DNS's impact on broad sensory processing skills in CP.
- Conditions
- DNS, Cerebral Palsy, Sensory Processing Disorder, Gross Motor Function
- Trial name
- NCT07729800
- Testing
- Reflex mediated core stability exercise, conventional therapy
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
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