Clinical trials: Brain Imaging
Disorder of Consciousness
Effects of Emotional Stimuli in Patients With Disorders of Consciousness
Disentangling the vegetative state from the minimally conscious state is often difficult when relying only on behavioral observation.
- Trial name
- NCT03502837
- Testing
- emotional sound and neutral sound
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Hearing Disorder
Brain Imaging of Tinnitus
This study will use magnetic resonance imaging (MRI) to compare brain function in three groups of people: hearing-impaired people with tinnitus; hearing-impaired people without tinnitus; and people with normal hearing and without…
- Trial name
- NCT00359931
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Narcolepsy, Amyloid Pathology
Narcolepsy Protect Against Alzheimer's Disease?
Links between orexin and amyloid processes have been underlined recently. During the Alzheimer's process an upregulation of the orexin mechanism has been observed.
- Trial name
- PROTECMAN (NCT03378453)
- Testing
- PET-scan18F-AV-45
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Montpellier
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness
fNIRS for Disorders of Consciousness
The goal of this observational study is to learn whether functional near-infrared spectroscopy (fNIRS) can measure brain activity in healthy adults and in people with disorders of consciousness (DoC) in the neuro-intensive care…
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness, Coma, Minimally Conscious State
- Trial name
- NCT07485361
- Testing
- Functional Near-Infrared Spectroscopy Monitoring
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Social Cognition, Expressed Emotion
Oxytocin, Emotions and Mirror Neurons
The purpose of this project is to investigate the possible effect of intranasally administered Oxytocin (OT) on specific mirror neuron areas in human brain.
- Trial name
- NCT02228031
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stroke, Cerebellum
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes.
- Trial name
- NCT06458153
- Testing
- Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Brain and Central Nervous System Tumors
Functional Magnetic Resonance Imaging and 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Treating Patients With Newly Diagnosed Brain Tumors
RATIONALE: New imaging procedures, such as functional magnetic resonance imaging and 1H-nuclear magnetic resonance spectroscopic imaging, may improve the ability to detect the extent of cancer in the brain.
- Trial name
- NCT00005083
- Testing
- conventional surgery, magnetic resonance imaging, magnetic resonance spectroscopic imaging
- Sponsor
- Jonsson Comprehensive Cancer Center
Cardiovascular and Cerebrovascular Diseases
Correlation Between Coronary Artery and Brain Study
To explore the pathogenesis of cardiovascular and cerebrovascular diseases through study on cardio-cerebral integration based on multimodal imaging technology, and clinical evaluation of its secondary diseases and intervention…
- Trial name
- NCT05813405
- Testing
- Experimental: Antihypertensive therapy Hypotension and improved ventilation treatment Intervention treatment for other risk factors
- Volunteers
- 1,000 people
- Sponsor
- Chinese PLA General Hospital
Central Nervous System Vulnerabilities in Preterm Infants
Comparison of Brain Volumes Measured by 2D USG and MRI
Cranial USG is simple and easy method to assess preterm infant brain. Some studies showed that brain volumes of preterm infants could be calculated by measurement of 2D distances.
- Trial name
- NCT04190017
- Testing
- Cranial MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Ankara City Hospital Bilkent
Thorax Injuries, Cervical Injury Spine
The Effect of Sensory Isolation on Anxiety in Magnetic Resonance Imaging
The aim of this study is to determine whether the use of earplugs and eye masks in adults reduces anxiety during Manyetic Resonance Imaging.
- Conditions
- Thorax Injuries, Cervical Injury Spine, Brain Trauma, Joint Trauma
- Trial name
- NCT07155863
- Testing
- Earplugs and eye mask
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ege University
Psychotic Disorder, Schizoaffecitve Disorder
Glycine to Treat Psychotic Disorders in Children
This study will test the safety and effectiveness of the amino acid glycine in treating psychotic disorders in children. The drug will be given as an adjunct (in addition) to the patient's current antipsychotic medication.
- Conditions
- Psychotic Disorder, Schizoaffecitve Disorder, Schizophrenia
- Trial name
- NCT00005658
- Testing
- Glycine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Mental Health (NIMH)
Premature Birth, Cerebral Palsy
Neuro-biomechanical Determinants for Motor Behavior in High-risk Infants
This project focuses on motor development, muscle growth and muscle activity. Using advanced, instrumented tests such as , the link between muscles and the movement characteristics will be studied.
- Conditions
- Premature Birth, Cerebral Palsy, Neurodevelopmental Disorders, Brain Injuries
- Trial name
- BAMBI (NCT06111898)
- Testing
- No Intervention
- Where
- Switzerland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Insulin Resistance, Menstrual Cycle
Effects of Antipsychotics on Brain Insulin Action in Females
Females treated with antipsychotics have higher rates of comorbid metabolic syndrome than males. Despite this, females have historically been excluded from many mechanistic studies due to confounding effects of menstrual cycles.
- Conditions
- Insulin Resistance, Menstrual Cycle, Type 2 Diabetes, Antipsychotics
- Trial name
- NCT06251635
- Testing
- Olanzapine 2.5Mg Oral Tablet, Insulin Lispro 100 UNT/ML, Saline
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Chronic Non-Specific Low Back Pain, Cognitive Decline
The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults
Chronic non-specific low back pain (CNSLBP) is a prevalent condition among older adult and has been associated with an increased risk of executive function impairment.
- Conditions
- Chronic Non-Specific Low Back Pain, Cognitive Decline, Cross-Sectional Study, Older Adults
- Trial name
- NCT06704425
- Testing
- For observational studies, participants are not assigned an intervention as part of the study.
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Traumatic Brain Injury, Chronic Traumatic Encephalopathy
Amyloid and Tauopathy PET Imaging in Acute and Chronic Traumatic Brain Injury
The potential long-term effects of Traumatic Brain Injury (TBI) are poorly understood. Repeated concussions have been associated with an elevated incidence of Alzheimer's disease (AD) along with a reduced age of onset.
- Conditions
- Traumatic Brain Injury, Chronic Traumatic Encephalopathy, Mild Cognitive Impairment
- Trial name
- NCT02266563
- Testing
- Amyvid PET Scan, T807 PET scan
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Samuel Gandy
Breast Cancer, Healthy
Impact of Cancer on Memory Functioning: Understanding Disorders Using Approaches in Neuropsychology and Neuroimaging
The purpose of this study is to investigate memory problems in patients with cancer.
- Trial name
- CANMEM (NCT01332916)
- Testing
- cognitive tests and cerebral IRM
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
MRI, PTX
MR7T-Healthy-PTX : Brain Exploration in Magnetic Resonance Imaging in Parallel Transmission Mode (pTX) at 7 Tesla
Magnetic resonance imaging (MRI) is a non-invasive imaging modality used in routine clinical practice for clinical diagnosis by visualizing the anatomical structure and in vivo function of certain organs.
- Conditions
- MRI, PTX, BRAIN, 7 TESLA
- Trial name
- NCT04369755
- Testing
- MRI
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Healthy
Pilot Study for the Effects of Transcranial Magnetic Stimulation on the Brain Using an Electronic Medical Device
This study is a randomized, double-blind, and sham-controlled trial to examine the effects of transcranial magnetic stimulation on the brain of health individuals.
- Trial name
- NCT02932085
- Testing
- Neurostar TMS Therapy System, NeuroStar XPLOR System
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University Mokdong Hospital
Pedophilia
Analysis of Cerebral Correlates of Pedophilia With Neuroimaging Techniques
The main objective is to identify cerebral correlated of pedophilia using neuroimaging techniques.
- Trial name
- PCNI (NCT02822664)
- Testing
- Pedophiles patients, Healthy subjects, PET/MRI
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Stroke, Cognitive Symptoms
Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)
Between 1 and 5 percent of patients who have coronary artery bypass surgery suffer a stroke following surgery, and 30 percent have new brain lesions that do not produce symptoms and are seen only on MRI.
- Trial name
- NCT00391378
- Where
- United States
- Volunteers
- 363 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)