Clinical trials: Brain Health
Parkinson Disease, Cognitive Impairment
Cognitive Training in Parkinson's Disease, the iPARK Study
The aim of the iPARK-study is to investigate the effects of a process-based cognitive training program with focus on working memory in patients with Parkinson's Disease (PD).
- Trial name
- iPARK (NCT03680170)
- Testing
- Working memory updating training
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Umeå University
Children With Cerebral Palsy Who Are Ambulant, Cerebral Palsy GMFCS-ER I-II
Exercise Training Among Children With Cerebral Palsy to Increase Health and Well-being - A Feasibility Study
The use of eHealth in children with cerebral palsy (CP) holds promise to increase participation in exercise. eHealth, has shown to increase accessibility to appropriate healthcare professionals as well as reduces time- and energy…
- Trial name
- HOME-EX (NCT07025694)
- Testing
- A eHealth application on a computer tablet contected to a secure severer with an interface on a computer to deliver exercise interventions., A eHealth application on a computer tablet contected to a secure severer with an interface on a computer to deliver exercise interventions, Moderate Intensity Continues Training
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lund University
Aging
Mindfulness Training in Healthy Older Veterans
Evidence shows the positive effects of Brain Health \& Wellness classes in younger individuals. The proposed study investigates the usefulness of these classes in older Veterans aged 50-85.
- Trial name
- MTGHOV (NCT02816723)
- Testing
- Mindfulness-based Stress Reduction, Brain Health
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Caregiver Burnout
Health enSuite Caregivers: an App-based Treatment for Distressed Caregivers of Persons With Moderate Dementia
Health enSuite Caregivers is an e-health program designed to meet some of the most common needs of caregivers of persons with dementia, including information about dementia and dementia care, caregivers' emotional health, formal…
- Trial name
- NCT04944420
- Testing
- Health enSuite Caregivers
- Volunteers
- 400 people
- Sponsor
- IWK Health Centre
Brain Function, Ultrasound
Effects of Infra- and Ultrasound on the Brain
Findings in neuroscientific research show that the environment one lives in has measurable effects on brain morphology and functioning.
- Conditions
- Brain Function, Ultrasound, Cognitive Function, Well-being
- Trial name
- NCT03459183
- Testing
- Infrasound (85 dB; 6Hz) source, Ultrasound (10dB below hearing threshold; 22.4 kHz) source, Infrasound dummy source
- Where
- Germany
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Education, Dementia
Reuptake of an E-Learning Programme in General Practice
The evaluate the use and diffusion of an E-learning programme in Diagnostic Evaluation of Dementia among General Practitioners (GPs) in Denmark. The hypothesis are: 1. The GPs do not use the guided instructions 2.
- Trial name
- NCT00392483
- Where
- Denmark
- Volunteers
- 3,632 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Stroke, Healthy Health Care Professionals
Usability and Acceptability Study of a Functional Electro-stimulator Controlled by Electromyographic Signal (FitFES)
Functional recovery of the upper limb after a cerebral stroke is one of the major critical issues in rehabilitation. The advent of innovative technologies can be helpful to rehabilitators and intervene where there is no other…
- Trial name
- NCT06763874
- Testing
- EMG-based FES device
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cognitive Impairment, Mild, Dementia, Mild
Buddy-Up Dyadic Physical Activity Program for Persons With Dementia and Family Caregivers
The global cost of dementia is over 818 billion, and a further rise is expected in the next decade. While family caregiving is the backbone of the formal care service, promoting "living well with dementia" needs to extend to a…
- Conditions
- Cognitive Impairment, Mild, Dementia, Mild, Dementia, Caregiver Burden
- Trial name
- BUDPA (NCT06584110)
- Testing
- Buddy-Up Dyadic Physical Activity (BUDPA) program, Usual care with waitlist control
- Where
- Hong Kong
- Volunteers
- 236 people
- Sponsor
- The University of Hong Kong
Rehabilitation, Stroke
Rehabilitation With Biofeedback for People After Stroke
The aim of the research will be to evaluate rehabilitation using the biofeedback method in people after stroke.
- Trial name
- NCT07333079
- Testing
- Biofeedback method using the Biometrics E-link (group I) and Stella Bio (group II) devices.
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Rzeszow
Parkinsonian Disorders
The National Registry Study For the Real-world Patients With Parkinsonian Disorders in China
The overall goal of this project is to identify, assess and longitudinally monitor subjects who are interested in participating in this study.
- Trial name
- ForPDCN (NCT03649503)
- Testing
- No intervention
- Where
- 2 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Depression in Old Age
Fitness for Brain Optimization for Late-Life Depression
Cognitive impairment and brain abnormalities are common and persist after depression remission in those with Late Life Depression (LLD), compounding dementia risk in both individuals with acute and remitted LLD (rLLD).
- Trial name
- FIT BOLD (NCT04670510)
- Testing
- On-site AE, At-home AE, Social Engagement (SE)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Pittsburgh
Stroke, Rehabilitation
Comprehensive Intensive Stroke Rehabilitation
In this study, the investigators aim to assess the effectiveness of the Comprehensive Intensive Rehabilitation Program After Stroke implementing the International Classification of Functioning, Disability and Health model, and to…
- Conditions
- Stroke, Rehabilitation, Physical Therapy Modalities
- Trial name
- COMIRESTROKE (NCT05323916)
- Testing
- Neuroproprioceptive "facilitation, inhibition", Technology based physical therapy, Effectively managed rehabilitation implementing the recommendations of the World Health Organization
- Where
- Czechia
- Volunteers
- 280 people
- Sponsor
- Charles University, Czech Republic
Parkinson's Disease
A US Study That Observes How Parkinson's Disease Changes Over Time in Patients Who Still Have Movement Symptoms Despite Taking Parkinson's Medications
This is an observational study in which data are collected and studied from Parkinson's disease patients who have movement symptoms despite taking standard Parkinson's medications.
- Trial name
- NCT07330258
- Testing
- Standard of Care
- Where
- 27 sites in United States
- Volunteers
- 300 people
- Sponsor
- Bayer
Bardet-Biedl Syndrome
Characterizing the Genotype and Phenotype in Adults With Bardet-Biedl Syndrome
Bardet-Biedl syndrome (BBS; OMIN #209900) is a rare genetic disorder characterized by six core features: rod-cone dystrophy (retinitis pigmentosa), polydactyly, obesity, genital anomalies, renal anomalies, and learning…
- Trial name
- NCT05400278
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Oslo University Hospital
Aging, Postmenopause
Oral Antioxidant Therapy Targeted to the Mitochondria for Improving Brain Artery Health in Postmenopausal Women
The goal of this clinical trial is to learn if 3 months of taking the dietary supplement MitoQ [a mitochondria-targeted antioxidant that targets to reduce mitochondrial reactive oxygen species (mitoROS)] works to treat age- and…
- Trial name
- NCT07406243
- Testing
- Mitoquinone (MitoQ)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Colorado State University
Dementia
Development and Evaluation of the DEA App
Background, current situation, and motivation According to current estimates, 100,000 people in Austria suffer from various types of dementia.
- Trial name
- DEA (NCT03819816)
- Testing
- DEA-App, Standard Information group
- Where
- 2 sites in Austria
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valentin Ritschl
Cerebral Palsy, Brain Injuries
The LETS Study: A Longitudinal Evaluation of Transition Services
This project will describe and evaluate the impact of a unique partnership model designed to coordinate transfer of care by formally linking pediatric and adult heath care services.
- Conditions
- Cerebral Palsy, Brain Injuries, Spinal Dysraphism
- Trial name
- LETS (NCT00975338)
- Testing
- LIFEspan, Non-LIFEspan
- Where
- 2 sites in Canada
- Volunteers
- 149 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Menopause, Perimenopause
Effects of a Synbiotic Intervention on Perimenopausal/Menopausal Symptoms
FemmeBiome Meno is a synbiotic supplement, meaning it contains both probiotics (beneficial bacteria) and prebiotics (a special kind of fiber that feeds these bacteria).
- Conditions
- Menopause, Perimenopause, Perimenopausal Women
- Trial name
- NCT07759908
- Testing
- Femmebiome Meno
- Where
- Ireland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University College Cork
Huntington Disease
Multi-Modal Digital Monitoring of Disease Symptoms Huntington's Disease
The objective of the study is to validate the use of wearable sensors and digital health technologies for monitoring disease activity in Huntington's Disease (HD).
- Trial name
- BioDigit HD-02 (NCT07315984)
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- BioSensics