Clinical trials: Brain Connectivity
Obesity, Eating Behaviour
The Effect of Neurofeedback on Eating Behaviour
Neuroimaging is becoming increasingly common to investigate the neural networks underlying eating behaviour and food preference in normal-weight and obese humans.
- Trial name
- NCT02148770
- Testing
- Neurofeedback
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Methamphetamine-dependence
Pilot Study of the Effect of Ibudilast on Neuroinflammation in Methamphetamine Users
Addiction to methamphetamine is a serious health problem in the United States. Right now, there are no medications that a doctor can give someone to help them stop using methamphetamine.
- Trial name
- Ibudilast (NCT03341078)
- Testing
- Ibudilast
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy
Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive…
- Trial name
- NCT07665216
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Injury;Sports
Acute Effect of Motor-Cognitive Training
Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes).
- Trial name
- NCT06017154
- Testing
- Motor-Cognitive Training Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ke'La H Porter
Healthy
Physiology of Human Brain Connectivity
The purpose of this study is to investigate the effective connectivity between different regions of the human brain in healthy participants, and the mechanisms which influence and modulate its development.
- Trial name
- NCT06246942
- Testing
- Single-pulse transcranial magnetic stimulation (spTMS), Paired associative stimulation (PAS), Magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Parkinson Disease Psychosis
Hallucinations in Parkinson's Disease
Investigation on how robotically mediated sensorimotor stimulation induces and triggers presence hallucinations in different clinical groups of parkinsonian patients, and in aged-matched controls
- Trial name
- NCT04592965
- Testing
- Clinical and neuropsychological assessments, Induction of PH and associated bodily states, Resting-state fMRI acquisition
- Where
- 6 sites in Spain, Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Olaf Blanke
Premature Ejaculation, Sexual Dysfunction
Brain Networks Implicated in Lifelong Premature Ejaculation Patients
Using Brain Mapping and Cognitive ERPs, the investigatos have searched for a Brain Networks involved during Inhibitory Control in Lifelong Premature Ejaculation (LPE) participants.
- Trial name
- LPE (NCT04850703)
- Testing
- Transcranial Radom Noise Stimulation, Take Dapoxetine, Compare LPE EEG endophenotype between participants and healthy controls
- Where
- Spain
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Moises Domingo
Bipolar Disorder, NOS
Brain Connectivity and Mindfulness Training in Youth With Bipolar Disorder Not Otherwise Specified (NOS)
The investigators propose to study 30 adolescents with bipolar disorder, not otherwise specified (BD NOS) and a family history of Bipolar I Disorder (BD) at baseline with rs-fMRI (functional magnetic resonance imaging) and…
- Trial name
- NCT02435225
- Testing
- Mindfulness Based Stress Reduction for Teens Group
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Stanford University
Normoxia, Intermittent Moderate Hypoxia
Brain Connectivity and Corticospinal Excitability in Response to Moderate Hypoxia
Hypoxia, defined as a reduction in the availability of oxygen, induces significant physiological adaptations. While the deleterious effects of severe and chronic hypoxia are well documented, several studies indicate that moderate…
- Conditions
- Normoxia, Intermittent Moderate Hypoxia, Continuous Moderate Hypoxia
- Trial name
- NEUROXIE (NCT07516028)
- Testing
- Moderate hypoxia, Normoxia, Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Neural Activity, Brain Function
Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation
The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it…
- Conditions
- Neural Activity, Brain Function, Neurodynamics, Brain Connectivity
- Trial name
- NCT06910293
- Testing
- Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Falling, Community Dwelling Older Adults
Neurophysiological Changes After Perturbation-based Training in Older Adults
This is an assessor-blinded neurophysiological study. Participants will be randomly assigned to a perturbation-based training (PBT) or a walking (control) group.
- Conditions
- Falling, Community Dwelling Older Adults, Postural Stability, Brain Connectivity
- Trial name
- NCT06573658
- Testing
- Perturbation-based balance training (PBT), Walking exercise (control)
- Where
- Hong Kong
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Progressive Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Study by Magnetic Resonance Imaging in the Progressive Forms of Multiple Sclerosis
The goal of this study is to show pattern differences of vasoreactivity and connectivity between Progressive Multiple Sclerosis and Relapsing Remitting Multiple Sclerosis, by the use of methods of advanced brain MRIs and the…
- Trial name
- VASOSEP (NCT02580669)
- Testing
- Neuropsychological assessment, Neurologic consultation, MRIs (with vasoreactivity testing)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Healthy
Brain Activity in Visual-Motor Behavior
This study will examine how the brain works when people look at an object, follow a moving object with their eyes, and reach out their hand to an object.
- Trial name
- NCT00077038
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Brain Tumor
Evaluation of Changes in Brain Connectivity After Tumor Resection
This study is being done to see the changes in structural and functional connectivity that happen in the brain of patients undergoing brain tumor surgery.
- Trial name
- NCT04536142
- Testing
- MRI, neuropsychological tests and qualitative assessment
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Schizophrenia, Psychosis
Glutamate, Brain Connectivity and Duration of Untreated Psychosis
The early stages of schizophrenia are associated with significant decreases in social and intellectual abilities, with more declines in chronic disease.
- Conditions
- Schizophrenia, Psychosis, Schizoaffective Disorder
- Trial name
- DUP (NCT02034253)
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Stroke
Brain Connectivity Measured With High-density Electroencephalography
Emerging scientific results show that disrupted functional connectivity in stroke can explain behavioral impairments and predict their recovery over time.
- Trial name
- NEUROCONN (NCT06298097)
- Testing
- Connectivity measures
- Where
- Italy
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Depressive Disorder, Treatment-Resistant
Brain Connectivity and Inflammatory Markers During Short-Term Psychotherapy for Treatment-Resistant Depression
Some adults continue to experience depression despite treatment with antidepressant medicines. This study aimed to explore relationships between depression symptoms, brain function, and blood markers of inflammation, and changes…
- Trial name
- NCT07847242
- Testing
- Short-Term Dynamic Psychotherapy, Mindfulness-Based Cognitive Therapy
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Korea University Ansan Hospital
Cluster Headache, Headache Disorders
Resting State Functional Connectivity in Cluster Headache
Cluster headache is a highly disabling primary headache disorder, characterized by severe, excruciating, recurrent unilateral headache attacks.
- Trial name
- NCT06206772
- Testing
- Resting state HD-EEG recording
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Insulin Resistance, Obesity
Enhancing Brain Health by TDCS in Persons with Overweight and Obesity
Disturbances in the hypothalamus communication pathways with other regions in the brain and the periphery may represent a potential link between metabolic and cognitive health.
- Conditions
- Insulin Resistance, Obesity, Diabetes Type 2
- Trial name
- STIM (NCT05228067)
- Testing
- anodal transcranial direct current stimulation, cathodal transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Development, Child, Executive Functions
Orchestra in Class, a Novel Booster for Executive Functions and Brain Development in Young Primary School Children
How to optimally stimulate the developing brain is still unclear. Executive functions (EF) exhibited substantially stronger far transfer effects in children who learned to play a musical instrument than in children who acquired…
- Conditions
- Development, Child, Executive Functions, Interventions, Music
- Trial name
- ORBIT (NCT05912270)
- Testing
- Orchestra in Class
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva