Clinical trials: Brain Computer Interface
Rehabilitation, Stroke
the Effectiveness of Brain-computer Interface-pedaling Training System on the Rehabilitation of Stroke
Stroke has become the first cause of death and disability among Chinese adults. 70%-80% of patients cannot live independently due to disability, which has brought a heavy burden to families, medical institutions and society.
- Conditions
- Rehabilitation, Stroke, Brain-computer Interface
- Trial name
- BCI-PT (NCT04612426)
- Testing
- Brain-computer Interface-Pedaling Training System, Traditional Pedaling Training System
- Where
- China
- Volunteers
- 30 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Stroke, Hemiplegia
Brain-controlled Spinal Cord Stimulation in Participants With Chronic Stroke for Lower and Upper Limb Rehabilitation
The purpose of this clinical study is to evaluate the preliminary safety and effectiveness of using a cortical recording device (ECoG) combined with cervical and lumbar targeted epidural electrical stimulation (EES) of the spinal…
- Trial name
- Stroke-BSI (NCT07610850)
- Testing
- ARC-BSI Stroke system
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Drug Resistant Epilepsy, Brain-Computer Interfaces
StereoEEG Motor Neuronal Potentials Decoding
The goals of this study are (1) to evaluate the rate of stereoEEG brain-computer interface (BCI) classification accuracy and (2) to collect the dataset of neuronal signals recorded from stereoEEG electrodes during motor…
- Trial name
- NCT06432907
- Testing
- motor tasks
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Research Center of Neurology, Russia
Autism Spectrum Disorder
BCI (Brain Computer Interface) Intervention in Autism
This study aims to demonstrate that improvements in identification of social clues (and improvement of overall social behaviour) in subjects with ASD can be achieved using social games together with a BCI setup.
- Trial name
- BCIAUT (NCT02445625)
- Testing
- BCI to train joint attention in ASD
- Volunteers
- 15 people
- Sponsor
- University of Coimbra
Depression, Major Depressive Disorder
Non-invasive BCI and Application Verification for Depressed People
Major Depressive Disorder (MDD) is a serious mental illness and public health problem that poses threat to both physical and mental health.
- Conditions
- Depression, Major Depressive Disorder, Bipolar Depression
- Trial name
- NCT06417437
- Testing
- SSRI, rTMS, Neuro-Feedback
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Locked-in Syndrome
Brain-Computer Interface Implant for Severe Communication Disability
Locked-In Syndrome (LIS) is a devastating condition in which a person has lost the ability to communicate due to motor impairment, while being mentally intact.
- Trial name
- NCT04576650
- Testing
- Summit System
- Where
- United States
- Sponsor
- Johns Hopkins University
Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline
Mild Cognitive Impairment Community Screening and Early Intervention Via Stem Cell Therapy and Wearable Brain Computer Interface Device.
This study aims to evaluate the efficacy of community-based early detection and targeted interventions, including stem cell therapy and wearable non-invasive brain-computer interface (BCI) devices, for Mild Cognitive Impairment…
- Conditions
- Mild Cognitive Impairment (MCI), Early Stages of Cognitive Decline, Alzheimer's Disease Dementia, Alzheimer's Disease Diagnosis
- Trial name
- MCITestCare (NCT07214974)
- Testing
- Structured wellness care, Wearable brain-computer interface devices, Stem Cell Therapy - Experimental
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Noah Tech, Corp.
Quadriplegia
Visuomotor Prosthetic for Paralysis
The investigators objective is to run human clinical trials in which brain activity recorded through a "brain-chip" implanted in the human brain can be used to provide novel communication capabilities to severely paralyzed…
- Trial name
- NCT01958086
- Testing
- Neural Communication System
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Richard A. Andersen, PhD
Stroke, Complication, Stroke
Neuromotor Prosthetic to Treat Stroke-Related Paresis
The purpose of the research is to develop a new medical device prototype to restore functional movement of an arm made weak due to a chronic stroke
- Conditions
- Stroke, Complication, Stroke, Stroke Sequelae, Hemiparesis
- Trial name
- Cortimo (NCT03913286)
- Testing
- Cortimo
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Thomas Jefferson University
Cerebral Palsy, Pediatric Stroke
BCI@Home: Brain Computer Interface Solutions to Enable Youth Living With Severe Disabilities
The goal of this trial is to evaluate use of brain computer interfaces (BCI) at home for children with severe severe physical disabilities. The main questions it aims to answer are: 1.
- Conditions
- Cerebral Palsy, Pediatric Stroke, Genetic Condition, Acquired Brain Injury (Including Stroke)
- Trial name
- BCI@home (NCT07073378)
- Testing
- Brain computer interface
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- University of Calgary
Tetraplegia, Quadriplegia
Investigation on the Bidirectional Cortical Neuroprosthetic System
The Bidirectional Cortical Neuroprosthetic System (BiCNS) consists of NeuroPort Microelectrode Array Systems and NeuroPort Electrodes (Sputtered Iridium Oxide Film), Patient Pedestals, the NeuroPort BioPotential Signal Processing…
- Trial name
- BiCNS (NCT03161067)
- Testing
- BiCNS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Amyotrophic Lateral Sclerosis, Neuromuscular Disease
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI).
- Conditions
- Amyotrophic Lateral Sclerosis, Neuromuscular Disease, Stroke, Tetraplegia/Tetraparesis
- Trial name
- CONNECT-ONE (NCT07357428)
- Testing
- Connexus Brain-Computer Interface
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Paradromics
Amyotrophic Lateral Sclerosis, Brain Stem Stroke
Real World Testing of a Brain-Computer Interface
The goal of this project is to test a new AAC-BCI device comparing gel and dry electrode headgear used for communication while providing clinical care.
- Conditions
- Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury
- Trial name
- NCT04026581
- Testing
- Speech generating device (SGD) evaluation including BCI access, Training and treatment
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Complete Locked-in State
Brain Computer Interface Complete locked-in State Communication
Electroencephalography (EEG) and/or near-infrared spectroscopy (NIRS) based Brain computer interface for communication in patients without any means of communication.
- Trial name
- NCT02980380
- Testing
- Non-invasive brain computer interface
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Tuebingen
Amyotrophic Lateral Sclerosis
Restore Motor Function Through Robotic Arm Exoskeleton and Brain Computer Interface
The current project will aid patients with motor impairment to reduce the need for homecare. Specifically the aim is to develop and implement a robotic exoskeleton and brain computer interface to assist and eventually perform arm…
- Trial name
- REMAP (NCT03900247)
- Testing
- REMAP EEG based BCI and SEM-Glove BioServo
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Healthy
Brain Computer Interface Control of a Robotic Device
Noninvasive Brain-Computer Interfaces (BCIs) have been used to control a number of virtual and physical objects through the voluntary modulation of brain rhythms.
- Trial name
- NCT02069938
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Acute Ischemic Stroke, Stroke Rehabilitation
Safety and Efficacy of Early Non-invasive Brain-Computer Interface-Based Rehabilitation in Acute Ischemic Stroke
This is a single-center, prospective, randomized, sham-controlled pilot clinical study designed to evaluate the efficacy, safety, and feasibility of early non-invasive electroencephalography-based brain-computer interface…
- Trial name
- SeeBCI (NCT07585058)
- Testing
- Real EEG-BCI Training, Standard Early Rehabilitation
- Volunteers
- 60 people
- Sponsor
- Shandong Provincial Hospital
Stroke, Stroke Acute
Research on the Effectiveness of Neurorehabilitation After Stroke
This clinical trial aims to investigate the effectiveness of a novel neurorehabilitation technology for treating stroke in adults.
- Conditions
- Stroke, Stroke Acute, Stroke with Hemiparesis, Stroke, Acute
- Trial name
- NCT06753006
- Testing
- Neurorehabilitation simulator, Standard course
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Neurotechnika
Depressive Sympotoms
Real-Time EEG Neurofeedback Using a Subject-Independent Classifier in Women With Depressive Symptoms
This completed feasibility study examined whether right-handed women aged 18-35 years with mild-to-moderate depressive symptoms could use real-time electroencephalography (EEG) neurofeedback based on a subject-independent…
- Trial name
- SIC-EEG-NF (NCT07815457)
- Testing
- Contingent Subject-Independent Classifier-Based EEG Neurofeedback
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Stroke, Motor Disorders
BCI-assisted MI Intervention in Subacute Stroke
Stroke is a leading cause of long-term disability. Cost-effective post-stroke rehabilitation programs are critically needed. Brain-Computer Interface (BCI) systems which enable the modulation of EEG sensorimotor rhythms are…
- Trial name
- Promotoer (NCT04353297)
- Testing
- EEG-based BCI system for (hand) Motor Imagery training, Motor Imagery training
- Where
- Italy
- Volunteers
- 49 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia