Clinical trials: Bowel Preparation Before Colonoscopy
Bowel Preparation for Colonoscopy
Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing
Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy.
- Trial name
- NCT06728839
- Testing
- 1L PEG + 50g magnesium sulfate, 3L PEG, 4L PEG
- Volunteers
- 1,329 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Esophagogastroduodenoscopy, Colonoscopy
Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation
The purpose of this study is to determine residual gastric volume and residual gastric pH in patients undergoing combined EGD and colonoscopy comparing the standard single dose prep with the split dose bowel preparation and same…
- Trial name
- NCT02264249
- Testing
- Esophagogastroduodenoscopy and colonoscopy split dose prep, Esophagogastroduodenoscopy and colonoscopy Evening before colonoscopy prep, Esophagogastroduodenoscopy and colonoscopy Same day prep colonoscopy preparation
- Where
- United States
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Colonoscopy, Bowel Preparation
Evaluation of an Oral Sodium Sulfate Solution for Patients With Prior Difficult or Incomplete Cleansing
This case series aims to evaluate the effectiveness and tolerability of Oral Sulfate Solution (OSS) in patients who had previously experienced poor colonoscopy preparation.
- Trial name
- OSS (NCT06051955)
- Testing
- oral sodium sulfate
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Lawrence Charles Hookey
Colonoscopy Preparation
4-L Split-dose Polyethylene Glycol and Bisacodyl and Docusate Sodium Regimen Versus 2-L Split-dose Polyethylene Glycol Plus Oral Simethicone Regimen for Bowel Preparation Before Colonoscopy
The goal of this randomized controlled trial is to compare the safety, compliance, and efficacy of different bowel preparation methods prior to colonoscopy.
- Trial name
- NCT07328880
- Testing
- 4-L split-dose polyethylene glycol and Bisacodyl + Docusate sodium., 2-L split-dose polyethylene glycol plus Oral Simethicone regimen ., 2-L split-dose polyethylene glycol regimen
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- Tanta University
Colorectal Neoplasms
Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy
Polyethylene glycol is the gold standard of bowel preparation for colonoscopy. The most important disadvantage is high volume of this preparation.
- Trial name
- NCT03242369
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Military University Hospital, Prague
Colon Cleansing
PMC Split Preparation for Colon Cleansing
This is an endoscopist-blinded, prospective, multicenter study involving adult outpatients aiming at evaluating whether sodium picosulphate/magnesium citrate split dosing is associated to higher efficacy and acceptability in…
- Trial name
- MAGIC-P (NCT01909219)
- Testing
- Sodium picosulphate/magnesium Citrate
- Where
- 2 sites in Italy
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Luigi Sacco University Hospital
Bowel Preparation Quality, Colonoscopy
The Effect of Video-Based Education on Colonoscopy Preparation
Colonoscopy is a routine procedure for evaluating gastrointestinal symptoms, detecting colorectal cancer, and removing polyps. Its effectiveness depends on patient compliance with bowel preparation instructions.
- Conditions
- Bowel Preparation Quality, Colonoscopy, Patient Education
- Trial name
- NCT07229066
- Testing
- Video Education
- Where
- Turkey (Türkiye)
- Volunteers
- 246 people
- Sponsor
- Eskisehir Osmangazi University
Colonoscopy, Bowel Preparation
Effect of Gum Chewing or Walking on Bowel Prep Quality and Patient Satisfaction Before Colonoscopy
Colorectal cancers are a major global health problem, highlighting the critical importance of screening programs for early diagnosis and effective treatment.
- Trial name
- NCT06192394
- Testing
- Chewing Gum, Walking Exercise, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Istanbul University - Cerrahpasa
Colonic Polyp, Colon Cancer
Improving Outpatient Colonoscopy Bowel Prep With the Orton Score
Colonoscopy is a common endoscopic procedure which the UVA Gastroenterology \& Hepatology department performs on a daily basis for both screening/surveillance and diagnostic/therapeutic intent.
- Trial name
- NCT04093557
- Testing
- Orton Score, Typical Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Bowel Preparation
Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic…
- Trial name
- NCT05137145
- Testing
- Linaclotide, Compound Polyethylene Glycol Electrolyte Powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Bowel Preparation Before Colonoscopy
A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children
A randomised, single-blind, active controlled, multi-centre trial to evaluate the efficacy, safety, tolerability, acceptability and palatability of PMF104 compared to a conventional PEG-electrolyte solution in paediatric subjects…
- Trial name
- NCT03106922
- Testing
- PMF104, Klean-prep
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 430 people
- Sponsor
- Alfasigma S.p.A.
Colonoscopy, Bowel Cleansing
The Effect of pH Value of Water Consumed During Bowel Preparation Before Colonoscopy on Colon Cleansing
Colonoscopy is a commonly used minimally invasive method for evaluating the lower gastrointestinal tract. The quality of colonoscopy is assessed by factors such as cecal intubation rate and adenoma detection rate, both of which…
- Conditions
- Colonoscopy, Bowel Cleansing, Water Intake, pH
- Trial name
- NCT07669116
- Testing
- Colon preparation for colonoscopy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sinan Ömeroğlu, MD
Bowel Preparation
Study of the Efficacy and Safety of Quiklean® and Klean-Prep With Dulcolax® for the Bowel Preparation Prior to Colonoscopy
The objective is to demonstrate that investigational drug, Quiklean®, is not inferior to standard comparator, Klean-Prep with Dulcolax®, with respect to the overall quality of bowel preparation in subjects undergoing colonoscopy.
- Trial name
- NCT03992365
- Testing
- Quiklean® (sodium phosphate monobasic monohydrate, USP, and sodium phosphate dibasic anhydrous, USP), Polyethylene glycol 3350, sodium sulfate anhydrous, sodium bicarbonate, sodium chloride, potassium chloride, aspartame;Bisacodyl
- Where
- Taiwan
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
Bowel Cleansing Quality, Predictors
A Predictive Model for Inadequate Bowel Preparation Before Colonoscopy: Development and Validation
About 30% of patients were reported to suffer inadequate bowel preparation.
- Conditions
- Bowel Cleansing Quality, Predictors, Colonoscopy, Boston Bowel Preparation Scale
- Trial name
- NCT02726893
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,504 people
- Sponsor
- Shandong University
Colonoscopy, Bowel Preparation
Bowel Preparation Before Colonoscopy
Bowel preparation can be a troublesome procedure for patients undergoing colonoscopy. For patients with cardio-vascular and kidney disorders it may be dangerous with traditional bowel preparation with regard to salt and…
- Trial name
- NCT00675324
- Testing
- Laxabon, Fresubin Energy drink
- Where
- Sweden
- Volunteers
- 47 people
- Sponsor
- Karolinska Institutet
Colonoscopy
Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy
The purpose of this study is to compare the safety and efficacy of BLI4900 bowel preparation to an FDA-approved control as 2-day, split-dose bowel preparations prior to colonoscopy in adult patients.
- Trial name
- NCT04446312
- Testing
- Bowel Prep
- Where
- 34 sites in United States
- Volunteers
- 500 people
- Sponsor
- Braintree Laboratories
Colonoscopy
PEG Solution (Laxabon®) 4L Versus Senna Glycoside (Pursennid® Ex-Lax) 36mg and PEG Solution (Laxabon®) 2L for Large Bowel Cleansing Prior to Colonoscopy
The trial compares Laxabon® 4L versus Pursennid® Ex-Lax 36mg and 2L Laxabon® for large bowel cleansing prior to colonoscopy allocating patients planned for colonoscopy to one of the two cleansing regimens.
- Trial name
- TARE-05-073M (NCT00390598)
- Testing
- PEG (solution given 4 L), senna glycoside 36 mg and PEG (solution given 2 L)
- Where
- Sweden
- Volunteers
- 490 people
- Sponsor
- Umeå University
Bowel Preparation, Bowel Preparation for Colonoscopy
A Study to Investigate the Effect of a Meal At 6pm the Day Before the Colonoscopy on the Bowel Cleansing with Plenvu
Bowel cleansing prior to colonoscopy is crucial to be able to perform a high-quality examination. Therefore maximum efforts are made to achieve optimal bowel cleansing including diet restriction and refraining from day-before…
- Conditions
- Bowel Preparation, Bowel Preparation for Colonoscopy, Bowel Cleansing for Colonoscopy, Healthy
- Trial name
- DinNER1006 (NCT06651398)
- Testing
- Lenient diet
- Where
- Belgium
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bowel Preparation Before Colonoscopy
Improved Bowel Cleansing Method for Colonoscopy Based on High Risk Population of Bowel Preparation
The purpose of this study is to observe the difference in bowel preparation quality between compound sodium picosulfate#CSP combined with lactulose and polyethylene glycol electrolyte#PEG combined with lactulose in high-risk…
- Trial name
- NCT05498714
- Testing
- PEG+lactulose, CSP＋lactulose
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Renmin Hospital of Wuhan University
Ottawa Score, Adenoma
A Repeated Instruction by Telephone on the Day Before Colonoscopy to Patients Undergoing Colonoscopy
Cell phone retell the instruction of bowel preparation on the day before colonoscopy would help patient to prepare for colonoscopy and improve the quality of the bowel preparation.
- Trial name
- NCT01584817
- Testing
- telephone education
- Where
- China
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China