Clinical trials: Bone Resorption
Alveolar Bone Resorption
Vertical Ridge Augmentation Using Computer-guided Sandwich Osteotomy Technique
Researcher will introduce the trial to patients and provide full explanation of its aim and benefits in Arabic language. Patients will then be able to have an informed discussion with the researcher.
- Trial name
- RGD (NCT07028606)
- Testing
- Sandwich technique with xenograft, collagen membrane and simultaneous implant placement., Sandwich technique with (RGD), xenograft, collagen membrane and simultaneous implant placement.
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Al-Azhar University
Alveolar Bone Resorption, Socket Preservation
Effect of Hyaluronic Acid, With Demineralized Tooth Graft, in Socket Preservation, vs Demineralized Tooth Graft Alone.
Many dentists, clinicians and researchers have conducted numerous trials, and put several materials and procedures under the test, in an attempt to preserve vertical and/or horizontal extraction sockets dimensions.
- Conditions
- Alveolar Bone Resorption, Socket Preservation, Bone Resorption, Unrestorable Dentition
- Trial name
- NCT05613075
- Testing
- tooth extraction and socket preservation with demineralized tooth graft, tooth extraction and socket preservation with demineralized tooth graft with hyaluronic acid
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ridge Preservation, Post Extraction Alveolar Bone Resorption
Socket Preservation Technique Using Bovine Bone, Platelet Rich Fibrin Or A Combination Of Both: A Clinical, Radiographic And Histological Assesment At 4 Months
Post extraction alveolar bone resorption is one of the main challenges that face oral implantologists in their daily surgical practice (1).
- Trial name
- NCT05889377
- Testing
- Socket preservation
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Bone Resorption, Tooth Loss
Hyaluronic Acid Effect on Xenogenic Bone Healing
The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation.
- Trial name
- NCT04377256
- Testing
- Ridge preservation: Tooth extration and immediat bone grafting in the socket
- Where
- 2 sites in Lebanon
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Bone Resorption, Preserving the Alveolar Ridge
Radiographic Evaluation in Alveolar Preservation Using Platelet-rich Fibrin. Randomized Controlled Trial
This randomized controlled trial is designed to assess the use of platelet-rich fibrin (PRF), a biomaterial derived from a participant's own blood, in alveolar ridge preservation following premolar extraction for orthodontic…
- Trial name
- NCT06900036
- Testing
- Platelet-Rich Fibrin (PRF) Application for Alveolar Preservation
- Where
- Ecuador
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de Cuenca
Bone Loss, Bone Remodeling Disorder
Socket Preservation Using Dentin Graft Autogenous Dentin Graft With Collagen Sponge on Dental Implant Stability AUTOGENOUS TOOTH GRAFT WITH COLLAGEN SPONGE ON DENTAL IMPLANT STABILITY
The present study was performed to evaluate socket preservation using collagen sponge with autogenous dentin graft versus collagen sponge with de-mineralised freez-dried bone graft on dental implant stability
- Conditions
- Bone Loss, Bone Remodeling Disorder, Bone Resorption
- Trial name
- NCT06853392
- Testing
- Demineralized freeze dried allograft with collagen sponge, autogenous dentin graft with collagen sponge
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Marginal Bone Levels, Open Sinus Elevation
Marginal Bone Changes Around Dental Implant Placed With Open vs. Closed Sinus Elevation
Background: In cases with atrophic posterior maxilla, sinus elevation techniques are essential for a successful implant placement.
- Conditions
- Marginal Bone Levels, Open Sinus Elevation, Closed Sinus Elevation
- Trial name
- NCT06811337
- Testing
- Open Sinus Elevation, Closed Sinus Elevation
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Misr International University
Alveolar Bone Resorption, Tooth Extraction
Ridge Preservation Following Tooth Extraction
An animal study and our pilot human study demonstrated that placing a smooth-surface titanium bone screw (TBS) over the buccal plate of an extraction socket resulted in less dimensional changes of the alveolar ridge along with no…
- Trial name
- NCT05485194
- Testing
- Reducing dimensional changes following tooth extraction
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Bone Atrophy, Alveolar, Bone Loss
Tunnel Access for Horizontal Alveolar Ridge Augmentation
Minimally invasive procedures with the tunnel technique have been suggested to decrease patient post-operative discomfort and morbidity in oral bone regeneration.
- Conditions
- Bone Atrophy, Alveolar, Bone Loss, Bone Resorption, Alveolar Bone Loss
- Trial name
- NCT06424223
- Testing
- Horizontal Ridge augmentation
- Where
- Italy
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Bone Resorption, Bone Loss
Bone Response to Exercise and Energy Restriction in Young Adults
Cycling is commonly questioned whether it provides adequate mechanical strain on bone as many elite cyclists have been found to have a low bone mass.
- Trial name
- NCT04345250
- Testing
- Energy restriction
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Brock University
Alveolar Bone Resorption
Socket Shield Technique With or Without Flap Elevation
It is aimed to compare the bone changes and the amount of marginal bone loss after prosthetic loading around the immediately placed implants using the Socket Shield Technique with or without flap elevation.
- Trial name
- NCT05492838
- Testing
- Immediate implantation with the Socket Shield Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alveolar Bone Resorption
Guided Bone Regeneration in Alveolar Socket
Following tooth extraction, volumetric changes in the soft and hard tissues of the extraction site are expected to occur with considerable resorption of the alveolar bone in both the vertical and the horizontal dimensions.
- Trial name
- GBR_socket (NCT05577663)
- Testing
- Routine treatment of the extraction socket, Socket seal technique by a free gingival graft, Socket seal technique using a synthetic resorbable membrane
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Tooth Loss
Azento IIS 3 Year Outcomes Implant Study
The revised purpose of this study is to compare and evaluate the stability of the implant body, survival rate, bone-level changes, and the implant's soft-tissue outcomes over a period of 1 year.
- Trial name
- NCT04255342
- Testing
- Implant Placement and Temporary Crown using AstraTech Implant System EV, Final Crown Delivery
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Christopher Barwacz
Apical Periodontitis
Sclerostin Regulation in Apical Periodontitis Lesions in Apical Periodontitis Lesions
Our aim was to examine the relationship between inflammatory bone resorption associated with the severity of AP and gingival crevicular fluid (GCF) and blood sclerostin and PGE2 levels in cases of AP.
- Trial name
- NCT06512103
- Testing
- Apical periodontitis group
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Bariatric Surgery Candidate, Bone Loss
Healthy Body, Healthy Bones After Bariatric Surgery Trial
One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with…
- Conditions
- Bariatric Surgery Candidate, Bone Loss, Bone Resorption
- Trial name
- NCT04279392
- Testing
- Zoledronic Acid 5 mg/Bag 100 ml Inj
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Tooth Extraction Status Nos, Bone Loss
"Pontic-shield" Technique in Alveolar Ridge Preservation
Alveolar bone resorption after dental extraction frequently leads to situations in which long-term function and esthetic success of rehabilitations with dental implants is a challenge.
- Conditions
- Tooth Extraction Status Nos, Bone Loss, Bone Resorption
- Trial name
- NCT05240417
- Testing
- "Pontic-shield" technique, Alveolar ridge preservation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Alveolar Bone Resorption
Lateral Ridge Augmentation Using Two Graft Combination and a Cross-linked Collagen Membrane
To treat resorbed alveolar ridges, many surgical procedures are available in the literature such as ridge splitting, distraction osteogenesis, block grafting techniques and guided bone regeneration, which is the most documented…
- Trial name
- NCT06523686
- Testing
- Guided bone regeneration
- Where
- Lebanon
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Alveolar Cleft
Evaluation of Bilateral Alveolar Cleft Grafting With Micro Plate Stabilization Versus Conventional Grafting Technique
The aim of the study is to enhance the maxillary segments stability during graft healing using microplate fixation to be compared with conventional grafting technique regarding gained bone quality and quantity.
- Trial name
- NCT06523855
- Testing
- bilateral alveolar cleft grafting using iliac crest particulate and microplate fixation
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Alveolar Bone Resorption, Wound Heal
Alveolar Socket Healing With and Without PRGF
A single-centre randomised controlled pilot study involving 12-24 healthy adult patients for investigating dental extraction socket healing with and without plasma rich in growth factors (PRGF) taking place during early days of…
- Trial name
- NCT04383158
- Testing
- PRGF ENDORET® obtained from ENDORET® POST-EXTRACTION ALVEOLUS DENTAL KIT (KMU16)
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London