Clinical trials: Bone Markers
Chronic Kidney Diseases
Exercise On Bone Metabolism Markers In Chronic Kidney Disease
Sixty chronic kidney disease patients, Measurement of bone turnover markers done prior to the study and at the end of the study after 6 months.
- Trial name
- intervention (NCT07628621)
- Testing
- resisted exercise training on some resistance machines, treadmill exercise training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Badr University
Rheumatoid Arthritis, Psoriatic Arthritis
Endothelial Function, Inflammatory Disease Activity, and Bone and Cartilage Markers in Rheumatic Patients: The Influence of Antirheumatic Treatment
The aim of this study is to examine the associations between inflammatory disease activity and endothelial function in rheumatoid arthritis (RA) and spondyloarthritis patients treated with methotrexate and Tumor Necrosis Factor…
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Endothelial Dysfunction
- Trial name
- PSARA (NCT00902005)
- Where
- Norway
- Volunteers
- 145 people
- Sponsor
- Revmatismesykehuset AS
Healthy, Postmenopausal Women
Dried Plums and Chronic Disease Markers
This study evaluates whether the consumption of California dried plums can be beneficial to your health. Previous studies using dried plums have shown beneficial effects on bone and cardiovascular health.
- Trial name
- NCT02950402
- Testing
- Two Dried Plums per day, Six Dried Plums per day
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Class I Malocclusion, Other Periodontal Diseases
A Biotype Enhancing Strategy For The Patient Undergoing Accelerated Orthodontics
Numerous treatment protocols geared towards accelerating orthodontic treatment have emerged in the past few years as an appealing alternative for patients and practitioners.
- Conditions
- Class I Malocclusion, Other Periodontal Diseases, Thin Gingival Biotype
- Trial name
- NCT02866929
- Testing
- Decortication, Orthodontics, Mucograft
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Cardiac Surgery for Bypass Grafting
Pilot Study to Establish a Repertoire of Megakaryocyte Markers, Quantifiable by Spectral Flow Cytometry, in Bone Marrow and Circulating in Patients Undergoing Cardiac Surgery for Bypass Grafting
Megakaryopoiesis, the mechanism of blood platelet production, is difficult to assess in clinical practice as it relies solely on microscopic description.
- Trial name
- EPIMéCA (NCT07026851)
- Testing
- Blood and bone marrow sampling
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Relapse, Bite Force
''Comparative Evaluation of Change in Bite Force and Levels of Bone Turnover Markers CTX and BALP in Hyperdivergent and Hypodivergent Cases During Retention Phases-A Prospective Clinical Trial ''
Long-term studies have shown that various occlusal changes occur after the active phase of orthodontic treatment. some of these changes are unwanted changes and are considered as relapse The retention appliances are used to…
- Conditions
- Relapse, Bite Force, Biomarker
- Trial name
- NCT06456827
- Testing
- Bite force and Gcf
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Rubinstein-Taybi Syndrome
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants.
Rubinstein-Taybi syndrome (RSTS) is a rare and severe congenital developmental disorder characterized by congenital anomalies and intellectual disability with a long term memory deficit.
- Trial name
- GENEPI (NCT04122742)
- Testing
- skin biopsy for the primary fibroblast culture and a 15 ml blood sample (3 unnamed samples of 5ml) in each of the 4 SRT patients included., Generation of Induced Pluripotent Stem Cells (iPSC) from fibroblasts obtained by skin biopsy, Histone acetylation profiles of cells of SRT patients with CREBBP mutations
- Where
- France
- Volunteers
- 154 people
- Sponsor
- University Hospital, Bordeaux
Acromegaly
Surgical Versus Medical Treatment of Acromegaly
Evaluate biochemical differences in acromegalic patients treated with surgery versus somatostatin analogues (SMS) (after surgery or alone). Hypothesis: Treatment modality exhibit different biochemical responses in acromegaly.
- Trial name
- NCT01000090
- Where
- Denmark
- Volunteers
- 63 people
- Sponsor
- University of Aarhus
Osteoporosis
Determinants of Bone Mineral Density and Metabolic Syndrome in South Asian Indian Men
This study aims to examine the association between body composition with bone density and risk factors for cardiovascular disease and type 2 diabetes.
- Trial name
- NCT03600675
- Testing
- No intervention element, observational study.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Drexel University
Scoliosis, Scoliosis Idiopathic
Investigation of the Effects of Exercise and Kinesiological Taping on Spinal Deformities and Serum Markers in Individuals With Scoliosis
The aim of this study is to investigate the effects of Schroth exercises and kinesiological taping on spinal deformities and serum markers in young adults with scoliosis.
- Conditions
- Scoliosis, Scoliosis Idiopathic, Musculoskeletal Deformity
- Trial name
- NCT06341465
- Testing
- Just Exercise, Exercise, Taping
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Paget's Disease of Bone
18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone
18 F-fluoride Positron emission tomography (PET) is able to demonstrate and quantify the metabolic activity locally in the skeleton (1).
- Trial name
- NCT00306046
- Testing
- Bisphosphonate treatment
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
Post Menopausal Osteoporosis
SUMMIT Study: A Study of Persistence to Bonviva (Ibandronate) Once Monthly in Women With Post-Menopausal Osteoporosis.
This 2 arm study will assess the impact of bone marker feedback, using blood sampling and communication of results at week 5, on persistence to monthly Bonviva (150mg po) in women with post-menopausal osteoporosis.
- Trial name
- NCT00545480
- Testing
- ibandronate [Bonviva/Boniva]
- Where
- 190 sites in France
- Volunteers
- 596 people
- Sponsor
- Hoffmann-La Roche