Clinical trials: Bone Loss, Alveolar
Edentulous; Alveolar Process, Atrophy
Reliability of All on 4 Using 2 Zygomatic and 2 Conventional Implants vs All on 4 Implants for Rehabilitation of Maxilla
Oral rehabilitation by dental implants in the severely atrophic maxilla often represents a challenge. To overcome this difficulty, bone augmentation procedures such as sinus augmentation, guided bone regeneration (GBR), or…
- Trial name
- NCT05108324
- Testing
- zygomatic implant, conventional implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level
Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is an indoleamine synthesized and secreted by the pineal gland and other organs, such as the retina, bone marrow, and intestines in a circadian pattern.
- Trial name
- NCT04229719
- Testing
- N-acetyl-5-methoxytryptamine
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Periodontal Bone Loss
Platelet-rich Fibrin and Autogenous Bone vs Membrane and Autogenous Bone in Intrabony Defects
Currently, the most positive documented outcomes of periodontal regenerative therapy (PRT) in intrabony defects (IBDs) have been achieved with a combination of bone grafts ( BGs) and a regeneration material like membranes in…
- Trial name
- NCT04043754
- Testing
- Procedure/Surgery: Periodontal surgery with Membrane, Periodontal surgery with Platlet Rich fibrin
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Alveolar Bone Loss
Graftless Maxillary Sinus Augmentation With CGF Utilizing DIVA System
This study is intended to evaluate the efficiency of graftless maxillary sinus augmentation with concentrated growth factor (CGF) utilizing "dynamic implant valve approach" (DIVA) system.
- Trial name
- NCT02985645
- Testing
- maxillary sinus augmentation with CGF, "dynamic implant valve approach" - DIVA system
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Periodontal Disease, Periodontal Bone Loss
Osteoclast Impairment in Chronic Periodontitis by Regenerative Materials.
The present study is an effort to investigate the hypothesis that Platelet Rich Fibrin/Biphasic Calcium Phosphate may play a role in inhibiting osteoclasts differentiation and in bone loss.
- Conditions
- Periodontal Disease, Periodontal Bone Loss, Osteoclastic Bone Loss
- Trial name
- NCT03227367
- Testing
- other : PRF
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Dental Implant Failure, Periodontal Bone Loss
A Retrospective Analysis of Failures of Oral Implants
The purpose of this retrospective study is to investigate and identify factors associated with the failure of dental implants within the population rehabilitated with dental implants at the Folktandvården Specialistklinik in…
- Trial name
- NCT02369562
- Testing
- Evaluation of the failure rate of dental implants
- Where
- Sweden
- Volunteers
- 2,670 people, healthy volunteers welcome
- Sponsor
- Malmö University
Edentulous Alveolar Ridge, Bone Atrophy, Alveolar
Crestal vs Lateral Sinus Lift Augmentation
The aim of this randomised controlled trial (RCT) of split-mouth design was to compare patient preference and effectiveness of two different techniques for lifting the maxillary sinus: the crestal approach versus the lateral…
- Trial name
- NCT04111250
- Testing
- Maxillary sinus augmentation
- Where
- Albania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Alveolar Bone Loss
Autogenous Demineralized Dentin Graft Combined With Injectable PRF + Metronidazole Versus Autogenous Demineralized Dentin Graft Alone for Alveolar Ridge Preservation
The aim of this trial is to compare the effect of autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole (sticky demineralized tooth releasing metronidazole) versus autogenous demineralized…
- Trial name
- NCT05470673
- Testing
- Alveolar ridge preservation using autogenous demineralized dentin graft combined with injectable PRF loaded with metronidazole, Alveolar ridge preservation using autogenous demineralized dentin graft alone
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-Implant Marginal Bone Loss, Dental Implantation
CBCT Assessment of Marginal Bone Changes With Ozone Therapy
This study examined whether adding local gaseous ozone to standard dental implant treatment could reduce early bone loss around implants. Fifty adults requiring matched implants on opposite sides of the same jaw participated.
- Trial name
- ozone-ımplant (NCT07687641)
- Testing
- Gaseous Ozone Application, Conventional Implant Placement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alveolar Bone Loss
Mineralized and Partial Demineralized Dentin Graft Compared to FDBA
The bone grafting materials currently used in dentistry are autografts, allografts, xenografts, and alloplastic grafts. Among these different types of bone graft materials, autografts are considered to have the most predictable…
- Trial name
- NCT05311735
- Testing
- Freeze-Dried Bone Allograft control, Mineralized Dentin Graft, Partial-Demineralized Dentin Graft
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Edentulous; Alveolar Process, Atrophy, Healthy Adult Participants
Comparison of Nd Yag, Diode and Er:YAG Lasers vs Scalpel in Preprosthetic Vestibuloplasty: Vestibular Depth Gain
The aim of this study was to compare the clinical results obtained using the conventional approach versus the modern laser method, by recording postoperative results
- Conditions
- Edentulous; Alveolar Process, Atrophy, Healthy Adult Participants, Edentulous Alveolar Ridge With Labial Resorption
- Trial name
- 78/30102018 (NCT07462117)
- Testing
- vestibuloplasty for Nd-YAG group, diode vestibuloplasty, Er-YAG laser vestibuloplasty
- Where
- Romania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Bone Loss, Alveolar, Resorption, Bone
The Effect of Growth Factor on Implant Osseointegration
In this study, concentrated growth factor obtained by centrifuging the patient's own blood and advanced platelet-rich fibrin liquids were applied to the implant cavity and surface.
- Conditions
- Bone Loss, Alveolar, Resorption, Bone, Osseointegration Failure of Dental Implant
- Trial name
- NCT04879446
- Testing
- Concentrated growth factor(CGF), Advanced platelet rich fibrin (A-PRF), Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Uğur Can ÜNLÜGENÇ
Alveolar Bone Atrophy
Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting
A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard…
- Trial name
- Maxibone (NCT04297813)
- Testing
- Advanced medicinal Therapy (MSC combined with biomaterial), Autologous bone graft
- Where
- 6 sites in Denmark, France and 2 more
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Tooth Loss
Treatment of Post-Extraction Dehisced Socket - A Case Series Study
PURPOSE The purpose of this case series is to clinically, radiographically and histologically evaluate the treatment of dehiscence defects in extraction sockets using a minimally-invasive GBR technique that involves the…
- Trial name
- OSTEO2 (NCT02980211)
- Testing
- Alveolar Ridge Reconstruction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gustavo Avila-Ortiz DDS, MS, PhD
Alveolar Bone Loss, Partially Edentulous Jaw
Impact of Hyaluronic Acid and Bone Graft on Peri-Implant Tissue
This randomized controlled clinical trial aims to evaluate the effect of hyaluronic acid (HA) and particulate bone graft on the peri-implant tissue phenotype in patients receiving dental implants.
- Conditions
- Alveolar Bone Loss, Partially Edentulous Jaw, Dental Implant
- Trial name
- NCT07665281
- Testing
- Dental Implants with Hyaluronic Acid, Dental Implants with Hyaluronic Acid and Particulate Bone Graft, Standard Dental Implants Placement only
- Where
- 2 sites in Iraq
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw