Clinical trials: Bone Loss, Alveolar
Alveolar Bone Loss, Periodontal Diseases
GUIDOR® Growth Factor Enhanced Bone Graft Substitute for the Treatment of Periodontal Defects 6-months Post-Surgery
GUIDOR Growth Factor Enchanted Bone Graft Substitute (GFeBGS) when used in periodontal surgery will shown greater gum and bone regeneration when compare to bone graft substitute alone. Also, to find the optimal dose.
- Trial name
- NCT01728844
- Testing
- beta-tricalcium phosphate alone, GFeBGS 0.1%, GFeBGS 0.3%
- Where
- 6 sites in United States
- Volunteers
- 88 people
- Sponsor
- Sunstar Americas
Alveolar Bone Loss
Effectiveness of Alveolar Bone Preservation in Alveoli With Infectious Process
Alveolar ridge preservation (ARP) is a surgical technique that aims to minimize the degree of dimensional changes following extraction.
- Trial name
- NCT06661863
- Testing
- alveolar ridge preservation with bioactive glass, alveolar ridge preservation with autologous bone
- Where
- Ecuador
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD…
- Trial name
- NCT05188898
- Testing
- MINSD and Hyaluronic acid, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Alveolar Process Atrophy
Marginal Bone and Soft Tissue Alterations After Use of OsseoSpeed EV Profile Implants
Evaluation of the marginal bone and soft tissue alterations after the OsseoSpeed™ EV Profile implants placement in anterior maxilla.
- Trial name
- NCT04243421
- Testing
- Implantation
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Alveolar Bone Loss
Efficacy of Customized Zirconia Sheet vs PTFE as a Non-resorbable Barrier in Maxillary Alveolar Ridge Augmentation
The goal of this clinical trial is comparing the efficacy of custom-made zirconia sheet versus Polytetrafluoroethylene as a non-resorbable barrier in maxillary alveolar ridge augmentation.
- Trial name
- NCT06227455
- Testing
- Maxillary alveolar ridge augmentation
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Tooth Loss, Tooth Diseases
The Cortical Shield for Facial Bone Reconstruction
To evaluate a novel technique of bone regeneration and simultaneous implant placement in severely damaged sockets.
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries
- Trial name
- NCT04827693
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Tooth Extraction Status Nos, Bone Loss
"Pontic-shield" Technique in Alveolar Ridge Preservation
Alveolar bone resorption after dental extraction frequently leads to situations in which long-term function and esthetic success of rehabilitations with dental implants is a challenge.
- Conditions
- Tooth Extraction Status Nos, Bone Loss, Bone Resorption
- Trial name
- NCT05240417
- Testing
- "Pontic-shield" technique, Alveolar ridge preservation
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Periodontitis, Alveolar Bone Loss
Phase 3 Clinical Trial of Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2(Trafermin)
This study aims to verify the effectiveness of Trafermin (recombinant human basic fibroblast growth factor) in stimulating regeneration of periodontal tissue lost by periodontitis and to evaluate the safety of such stimulation.
- Conditions
- Periodontitis, Alveolar Bone Loss, Periodontal Attachment Loss
- Trial name
- NCT00734708
- Testing
- Trafermin (genetical recombination)
- Where
- 21 sites in Japan
- Volunteers
- 328 people
- Sponsor
- Kaken Pharmaceutical
Chronic Periodontitis, Periodontal Bone Loss
Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection.
The aim of the study is to develop an in vitro model of growth of oral biofilms, and validate xCELLigence system for the selection of an effective antibiotic treatment for each patient.
- Conditions
- Chronic Periodontitis, Periodontal Bone Loss, Resistance Bacterial
- Trial name
- NCT03863249
- Testing
- SCALE AND ROOT PLANING, ADJUNTIVE ANTIBIOTICS, MICROBIAL SAMPLING
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Valencia
Alveolar Bone Atrophy
Efficacy in Alveolar Bone Regeneration With Autologous MSCs and Biomaterial in Comparison to Autologous Bone Grafting
A randomized controlled clinical multi center trial to assess the efficacy of a combination of autologous mesenchymal stem cells and biomaterial in jaw bone regeneration prior to dental implant placement in comparison to standard…
- Trial name
- Maxibone (NCT04297813)
- Testing
- Advanced medicinal Therapy (MSC combined with biomaterial), Autologous bone graft
- Where
- 6 sites in Denmark, France and 2 more
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Alveolar Bone Loss, Dental Implant
Magnetic Mallet Vs Conventional Drilling in D4 Posterior Maxilla
The goal of this clinical trial is to evaluate whether the magnetic mallet technique improves primary implant stability and clinical outcomes compared with conventional drilling during dental implant placement in the posterior…
- Conditions
- Alveolar Bone Loss, Dental Implant, Osseodensification Drilling Technique
- Trial name
- NCT07424820
- Testing
- Conventional drilling osteotomy, Magnetic mallet osteotomy
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alveolar Ridge Deficiency, Alveolar Bone Loss
Novel Synthetic Membrane for Horizontal Bone Augmentation: A Case Series
The goal of this clinical study is to learn if the Inox Nanoksa G-Plus membrane works to rebuild bone in the upper or lower jaw (ridge augmentation) for adults who need dental implants but do not have enough bone width or height.
- Trial name
- NCT07701473
- Testing
- Inox Nanoksa G-Plus Membrane, Particulate Bone Graft
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Horizontal Alveolar Bone Loss
Horizontal Ridge Augmentation Using Polyvinylidene Fluoride Versus Titanium Mesh Membranes
This study aims to evaluate the effectiveness of a new PVDF non-resorbable membrane versus Titanium Mesh in the treatment of horizontal ridge defects prepared for implant placement
- Trial name
- PVDF + HRA (NCT07095530)
- Testing
- titanium membrane
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Minia University
Horizontal Atrophy of Edentulous Alveolar Ridge
Crestal Bone Loss Around Narrow Diameter Implants Versus Standard Diameter Implants With Bone Augmentation in Horizontally Deficient Posterior Mandibular Sites.
Dental implant treatment, in many cases, may be impeded by anatomical limitations, such as narrow atrophic ridges. In order to overcome that, additional surgical procedures, such as guided bone regeneration, are often required to…
- Trial name
- NCT06221306
- Testing
- Dental implant: NDI, Dental implant: SDI
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Vitamin D Deficiency, Alveolar Bone Loss
Vit D and Post-extractive Bone Turnover
The aims of the study was to correlate the extent of the dimensional alveolar bone changes after tooth extraction and contextual guided bone regeneration with serum vit D levels in 14 patients.
- Conditions
- Vitamin D Deficiency, Alveolar Bone Loss, Alveolar Bone Resorption
- Trial name
- NCT06412705
- Testing
- Tooth extraction, guided bone regeneration and dental implant
- Where
- Italy
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Studio Odontoiatrico Associato Dr. P. Cicchese e L. Canullo
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Bone Resorption, Alveolar Bone Loss
Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge
Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6…
- Conditions
- Bone Resorption, Alveolar Bone Loss, Alveolar Bone Resorption, Bone Graft Failure
- Trial name
- NCT03584984
- Testing
- Mixture of Autogenous bone & Anorganic Bovine Bone (ABB), Anorganic Bovine Bone (ABB), Absorbable gelatin sponge
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Implant Infection, Alveolar Bone Loss
Associations of Alveolar Bone Loss and Interleukin-1β Levels in One and Two Stage Surgical Procedures
The present study was compared the level of alveolar bone loss, clinical parameters and IL-1β in PICF in one- or two-stage surgical procedures.
- Trial name
- NCT03045458
- Testing
- tissue level dental implant, Bone level dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Firat University
Alveolar Bone Loss
Graftless Maxillary Sinus Augmentation With CGF Utilizing DIVA System
This study is intended to evaluate the efficiency of graftless maxillary sinus augmentation with concentrated growth factor (CGF) utilizing "dynamic implant valve approach" (DIVA) system.
- Trial name
- NCT02985645
- Testing
- maxillary sinus augmentation with CGF, "dynamic implant valve approach" - DIVA system
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya