Clinical trials: Bone Level
Partial Edentulism, Tooth Disease
Randomized Study of Integration Success of Osseotite Dental Implants Placed Using Different Insertion Procedures
Osseotite implants placed with higher insertion torque (TEST procedure) will have higher initial stability and integration success than those placed with lower insertion torque forces.
- Trial name
- Pegasus (NCT01529736)
- Testing
- High torque insertion, Low torque insertion
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- ZimVie
Cervical Vertebrae, Single
The Comparison Between the Stand-alone Cage and the Autologous Iliac Bone Graft/Anterior Plating in the Single-level Surgical Treatment of the Cervical Spine
The use of plate in addition to autologous bone is better then stand alone cage fusion regarding fusion rate and segmental lordosis.
- Conditions
- Cervical Vertebrae, Single, Degenerative Disease
- Trial name
- CAP_2014 (NCT02030899)
- Testing
- Cage fusion, Plate fusion
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Ergocalciferol
Pilot Study: The Effect of Ergocalciferol on Plasma Mucin-1 Levels
To determine if a one-time oral administration of ergocalciferol results in a decline in plasma mucin-1 levels in healthy individuals and individuals with ADTKD-MUC1.
- Trial name
- NCT03747523
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Missing Tooth
Effect of Slopped Shoulder Implant Neck vs Conventional Implant Neck Design on Crestal Bone Level in the Maxilla
In implant dentistry, platform switching is a method used to preserve alveolar bone levels around dental implants. The concept refers to using an implant with slopped shoulder neck of narrower diameter on implants of wider…
- Trial name
- NCT03614442
- Testing
- slopped shoulder implant
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
HIV
Effect of a Non-tenofovir, Non-efavirenz-based HIV Regimen on Bone Density and Vitamin D Levels in African-American Patients With HIV Infection
2. Objectives 1. To determine the vitamin D status of African-American HIV patients who are HIV-treatment naïve. 2. To compare the effects of an efavirenz-containing regimen to a protease inhibitor regimen on 25-hydroxyvitamin D…
- Trial name
- NCT01343225
- Testing
- atripla, darunavir ritonavir raltegravir
- Volunteers
- 40 people
- Sponsor
- East Carolina University
Any Cancer With Multiple Bone Metastases
Treatment of Opioid-refractory Pain (WHO Level III) by Pituitary Radiosurgery
80% of palliative care cancer patients suffer from severe pain. The management of these pain improves the quality of life of these patients. The management of opioid pain refractory to date remains a difficulty for caregivers.
- Trial name
- Hyporadoul (NCT02637479)
- Testing
- GammaKnife®, 18F-2-fluoro-2-deoxy-D-glucose - positron emission tomography (FDG-PET), MRI
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Psoriatic Arthritis (PsA)
Phase 2 Trial of FT2109 for the Treatment of Psoriatic Arthritis
This study will investigate if the study medicine FT2109 can treat symptoms of active Psoriatic Arthritis (PsA). This study assesses the safety and efficacy of FT2109 in adult participants with active PsA who may or may not have…
- Trial name
- NCT07869134
- Testing
- FT2109 Dosing Regimen 1, FT2109 Dosing Regimen 2
- Volunteers
- 210 people
- Sponsor
- Forward Therapeutics
Partial Edentulism, Tooth Loss
The Influence of the Crown-implant Ratio on the Crestal Bone Level and Implant Secondary Stability
The aim of the study was to determine whether implant length and the crown-to-implant (C/I) ratio influence implant stability and the loss of the surrounding marginal bone, and whether short implants can be used instead of sinus…
- Trial name
- NCT03471000
- Testing
- Short implants Treatment, Regular implants Treatment
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jakub Hadzik
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Implant Infection, Alveolar Bone Loss
Associations of Alveolar Bone Loss and Interleukin-1β Levels in One and Two Stage Surgical Procedures
The present study was compared the level of alveolar bone loss, clinical parameters and IL-1β in PICF in one- or two-stage surgical procedures.
- Trial name
- NCT03045458
- Testing
- tissue level dental implant, Bone level dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Firat University
Atrophy, Jaw, Edentulous, Partially
Comparative Results of Six Biomaterials Used in Two-stage Maxillary Sinus
Objectives: The aim of the study was to compare histological and histomorphometric results of six bone substitute materials used as graft in two-stage maxillary sinus augmentation model, after 6-month-healing.
- Conditions
- Atrophy, Jaw, Edentulous, Partially, Sinus Floor Augmentation, Bone Substitutes
- Trial name
- NCT03496688
- Testing
- Sinus floor augmentation
- Volunteers
- 6 people
- Sponsor
- University of Roma La Sapienza
Peri-Implant Health, Peri-Implant Tissues
Comparison Between Free Gingival Graft and Palatal Pedicle Flap
Patients requiring KMW gain(mm) during uncovering surgery were included. Two surgical methods were compared: apically position flap with free gingival graft (FGG group) and the palatal pedicle flap with collagen matrix (PPF…
- Conditions
- Peri-Implant Health, Peri-Implant Tissues, Peri-implant Bone Level
- Trial name
- Pedicle (NCT06816680)
- Testing
- APF + FGG, PPF group
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Lumbar Spinal Stenosis, Intervertebral Disc Degeneration
Minimally Invasive Decompression and Fusion Versus Open for Degenerative Lumbar Stenosis
The purpose of this study is to determine the effectiveness of minimally invasive decompression and fusion over the traditional open decompression and fusion in patients with single-level lumbar stenosis caused by degenerative…
- Trial name
- NCT04594980
- Testing
- lumbar fusion
- Where
- Russia
- Volunteers
- 96 people
- Sponsor
- N.N. Priorov National Medical Research Center of Traumatology and Orthopedics
Alveolar Ridge Augmentation
Effect of Low Level Laser Teraphy on Bone Regeneration
This randomized controlled split-mouth clinical trial study was designed to evaluate the effects of low-level laser therapy on bone healing in patients with bilateral sinus lifting and simultaneous dental implant application.
- Trial name
- NCT03179683
- Testing
- Diode laser application
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ugur GULSEN
Hyperparathyroidism; Secondary, Renal
Efficacy and Safety of Cinacalcet in Ca, P and iPTH Levels in Patients With Mild, Moderate and Severe SHPT
1. To evaluate achievement ratio of iPTH,Calcium and phosphorus after taking Cinacalcet HCL in hemodialysis subjects with mild, moderate and severe SHPT; 2.
- Trial name
- ACTIVE (NCT03123406)
- Testing
- Cinacalcet HCl
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Kyowa Kirin China Pharmaceutical Co., Ltd.
Sinus Floor Augmentation, Maxillary Sinus
Prospective Evaluation of Anorganic Bovine Bone Mineral Versus Calcium Phosphosilicate Alloplastic Bone Putty in Direct Sinus Augmentation: a Spilt-mouth Study
The purpose of this split-mouth clinical study is to evaluate the clinical, radiographic and histological outcomes of lateral window sinus augmentation with a bovine xenograft or a CPS putty bone substitute in posterior maxillary…
- Trial name
- NCT01942304
- Testing
- Calcium phosphosilicate alloplastic bone putty in direct sinus augmentation, Anorganic bovine bone mineral in direct sinus augmentation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Minnesota
Bone Loss, Implant Complication
The Effects of Dis/Reconnection of Implant Abutments on Peri-implant Bone Levels
The aim of this study was to evaluate the effects of definitive abutment connection at the time of implant placement on peri-implant bone levels and soft tissue changes in posterior maxilla and mandible regions.
- Conditions
- Bone Loss, Implant Complication, Gingival Recession
- Trial name
- NCT04043286
- Testing
- Definitive abutment
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Stage III Periodontitis
Evaluation of Serum TRACP-5b, BALP, and 25-Hydroxyvitamin D3 Levels in Stage III Periodontitis Patients
Periodontitis is a chronic inflammatory disease characterized by the progressive destruction of the supporting tissues of the teeth.
- Trial name
- TRACP-BALP-D3 (NCT07438977)
- Testing
- Non-Surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Ataturk University
Osteoporosis, Osteopenia
Study to Evaluate Effect of Intranasal Teriparatide on Serum P1NP, a Biomarker of Bone Formation, in Postmenopausal Women With Low Bone Mass
This study is being conducted to evaluate the effect treatment has on serum P1NP levels, a biomarker of bone formation in postmenopausal women with low bone mass.
- Trial name
- NCT01604057
- Testing
- ZT-034 Low Dose Nasal Spray, ZT-034 Mid Dose Nasal Spray, ZT-034 High Dose Nasal Spray
- Volunteers
- 130 people
- Sponsor
- Azelon Pharmaceuticals