Clinical trials: Bone Health, open to volunteers
Osteoporosis, Obesity
Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian Young Adults
Milk and dairy products contain significant amounts of nutrients that contribute to optimal health - nutrients like calcium, vitamin D, and high-quality protein.
- Trial name
- NCT06265246
- Testing
- Habitual Diet + Milk, Habitual Diet + Yogurt
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Polycythemia Vera, ET (Essential Thrombocythemia)
MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)
The MPN PROGRESSion Registry is a multi-year, observational research study designed to improve understanding of myeloproliferative neoplasms (MPNs)-a group of rare, chronic blood cancers that include polycythemia vera (PV)…
- Conditions
- Polycythemia Vera, ET (Essential Thrombocythemia), Polycythemia Vera (PV), Essential Thrombocythemia (ET)
- Trial name
- NCT07362225
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- MPN Research Foundation
Cognition, Muscle Strength
Dietary Supplements and Middle Aged Women (Creatine)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Muscle Strength, Fatigue Symptom, Blood Pressure and Augmentation Index
- Trial name
- NCT07729930
- Testing
- Creatine Monohydrate
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy, Psychological Well Being
Survey of Psychological Well-being of Health Care Workers in the Hospital Setting
The psychological well-being of healthcare workers in hospital settings is a topic of growing interest in the scientific literature, given the crucial importance of their role in ensuring high-quality care.
- Conditions
- Healthy, Psychological Well Being, Stress Response, Professional Quality of Life
- Trial name
- IN-VISIBLE (NCT06923436)
- Testing
- Psychological Assessment
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Psoriatic Arthritis (PsA), Liver Fibrosis
Comparison of Liver Health in Psoriatic Arthritis Patients Using Anti-TNF or Anti-IL17 Treatments
Psoriatic arthritis (PsA) is an inflammatory joint disease that can also affect the liver. Some medications used to treat PsA, such as biological agents (TNF-alpha inhibitors and IL-17 inhibitors), may influence liver health over…
- Conditions
- Psoriatic Arthritis (PsA), Liver Fibrosis, Liver Diseases
- Trial name
- FIB-4 PsA (NCT06918886)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bezmialem Vakif University
Psoriatic Arthritis (PsA)
Prevention of Psoriatic Arthritis Inflammation Through Digital Care: A Feasibility Mixed-Methods Study
This is an international, multicentre, feasibility mixed-methods, single-arm study evaluating the implementation of the iPROLEPSIS digital health promotion programme for adults with psoriatic arthritis (PsA) in real-world…
- Trial name
- PPIDC (NCT07772544)
- Testing
- iPROLEPSIS Digital Health Ecossystem
- Where
- 4 sites in Greece, Portugal
- Volunteers
- 72 people
- Sponsor
- Sociedade Portuguesa de Reumatologia
Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated
National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry
The goal of this observational study is to develop a registry of Brazilian patients with hereditary cardiovascular diseases, combining clinical and genomic data.
- Conditions
- Cardiomyopathy, Hypertrophic, Cardiomyopathy, Dilated, Cardiomyopathy Restrictive, Arrhythmogenic Right Ventricular Dysplasia
- Trial name
- RENOMICA-Hcor (NCT06546137)
- Testing
- whole genome sequencing
- Where
- 27 sites in Brazil
- Volunteers
- 1,211 people
- Sponsor
- Hospital do Coracao
Neoplasms, Connective and Soft Tissue, Bone Neoplasms
An Electronic Health Record (EHR)-Based Comprehensive Bone and Soft Tissue Tumor Registry
Translational studies in cancer research can be impeded by the lack of high-quality clinical data that can be correlated with research questions.
- Trial name
- NCT02677961
- Testing
- Observation
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Psoriatic Arthritis
Combined High-Intensity Aerobic Training and Resistance Training in Psoriatic Arthritis
The goal of this randomised controlled trial is to evaluate the effects of a 12-week intervention comprising high-intensity interval aerobic training and strength training on cardiovascular function, metabolic health profile and…
- Trial name
- PsA-HIIT (NCT07352696)
- Testing
- Exercise program
- Where
- 2 sites in Sweden
- Volunteers
- 88 people
- Sponsor
- Vastra Gotaland Region
Bone Conduction, Hearing Loss, Conductive
Post-market Evaluation of the Transition From the Baha Connect System to the Osia System in Adult Bone Conduction Implant Recipients
The goal of this interventional study is to confirm the safety and performance of the latest generation Osia System and to examine its benefits compared to the Baha Connect System in adults with mixed or conductive hearing loss…
- Conditions
- Bone Conduction, Hearing Loss, Conductive, Hearing Loss, Mixed
- Trial name
- OSIRIS (NCT07130136)
- Testing
- Cochlear™ Osia® System, Cochlear™ Baha® System
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Cochlear
Dietary Exposure, Diabetes Mellitus, Type 2
Cohort Study on Plant-based Diets (COPLANT Study)
The Cohort on Plant-based Diets (COPLANT) study is a multi-centre cohort study that starts baseline recruitment from 2024 to 2027 with approximately 6,000 participants in Germany and Austria.
- Conditions
- Dietary Exposure, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Bone Loss
- Trial name
- COPLANT (NCT06323538)
- Where
- 8 sites in Austria, Germany
- Volunteers
- 6,000 people
- Sponsor
- German Federal Institute for Risk Assessment
Scoliosis; Adolescence, Adolescent
Quality of Life (HRQoL) of AIS Patients Who Require Bracing or Surgery Using SRS-22 Questionnaire
Adolescent Idiopathic Scoliosis (AIS) is an unexpected curvature of spine at teenage. AIS causes mainly unpleasant appearance, and sometime comes with pain and difficult to locate or move around.
- Conditions
- Scoliosis; Adolescence, Adolescent, Quality of Life, SRS
- Trial name
- QolAISSRS22 (NCT03915106)
- Testing
- Brace, Surgical correction using implants
- Where
- Hong Kong
- Volunteers
- 2,000 people
- Sponsor
- Chinese University of Hong Kong
Chronic Myeloid Leukemia
Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia
The purpose of this study is to evaluate Efficacy and Safety of Generic Imatinib (Carcemia®) Compared to Glivec® in Real-Life Management of Chronic Phase of Chronic Myeloid Leukemia
- Trial name
- CARCML (NCT05282108)
- Testing
- Carcemia, Glivec
- Where
- 4 sites in Egypt
- Volunteers
- 240 people
- Sponsor
- Hikma Pharmaceuticals LLC
Osteoporosis
Artificial Intelligence-Guided Diagnosis for High-Risk Osteoporosis Populations: A Pragmatic Randomized Clinical Trial
Project Summary I. Project Objectives With the rapid advancement of medical technology, smart medical devices have become one of the key components of modern healthcare.
- Trial name
- NCT07620834
- Testing
- VeriOsteo OP
- Where
- 3 sites in Taiwan
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Bone Tumor, Bone Cancer
Medical Payment Case Management for Financial Toxicity in Patients With Primary Bone Tumors: A Randomized Controlled Trial
The goal of this clinical trial is to learn if adding a medical payment case management service to the hospital's usual follow-up care can reduce the financial hardship of cancer treatment in patients of any age, including…
- Trial name
- NCT07888244
- Testing
- Medical payment case management service
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Shanghai 6th People's Hospital
Dynapenia, Abdominal Obesity
Effectiveness of Whole Body Vibration on Health Outcomes in Older Adults With Dynapenic Abdominal Obesity
This study focuses on whole body vibration training (WBVT), a form of neuromuscular training that uses mechanical vibrations. WBVT has been shown to improve muscle function, bone mineral density, and quality of life.
- Trial name
- NCT07180485
- Testing
- whole body vibration training, control group
- Volunteers
- 120 people
- Sponsor
- Dalin Tzu Chi General Hospital
Musculoskeletal Health, Healthy Adult Volunteers
The Effects of the Yi Jin Jing on the Muscles and Bones of Adults
Observation of the effects of Yi Jin Jing on the muscles and bones of adults
- Trial name
- NCT07753291
- Testing
- Yijinjing
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital of Traditional Chinese Medicine
Femoral Neck Fractures, Undisplaced Fracture
Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients (HipSTHeR)
A registerbased RCT will investigate whether arthroplasty can decrease the reoperation rate compared to internal fixation for patients with an undisplaced femoral neck fracture (Garden I-II).
- Trial name
- HipSTHeR (NCT03966716)
- Testing
- Arthroplasty, Internal Fixation
- Where
- 25 sites in Sweden
- Volunteers
- 1,440 people
- Sponsor
- Uppsala University
Osteoporosis
Dairy vs Plant-based Beverages for Improving Bone Health During Exercise
This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral…
- Trial name
- NCT06946316
- Testing
- Nutritional supplementation during a 12 month resistance training program
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University