Clinical trials: Bone Fracture, active
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Bone Density, Bone Health
VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)
Vitamin D supplements are widely promoted for bone health. Both vitamin D and vitamin K are important for deposition of calcium in bone, but little is known about the relationship of vitamin K status and bone health.
- Conditions
- Bone Density, Bone Health, Fractures
- Trial name
- NCT04573946
- Testing
- Omega-3 fatty acids (fish oil), Vitamin D3
- Where
- United States
- Volunteers
- 25,871 people
- Sponsor
- Brigham and Women's Hospital
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Suicide Mortality
The Developmental Origins of Suicide Mortality
Background: Suicide rates are rising. In 2013, it was the third leading cause of death in children ages 10-14. It was the second leading cause of death for ages 15-24. Many risk factors for suicide have been found.
- Trial name
- NCT03027440
- Where
- United States
- Volunteers
- 52,966 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Fracture of Tibia
Conservative Versus Intramedullary Nailing for Pediatric Tibial Shaft Fractures
Tibial shaft fracture is a common fracture in the pediatric and adolescent population. The outcomes of both conservative and operative treatment are not clear and to date there is no randomized prospective trial comparing…
- Trial name
- CINPED (NCT05501496)
- Testing
- intramedullary nailing, casting
- Where
- 2 sites in Finland
- Volunteers
- 66 people
- Sponsor
- Turku University Hospital
Femoral Neck Fractures
Comparison of the Direct Anterior Approach (DAA) and the Direct Lateral Approach (DLA) in Patients Treated With Partial Hip Replacement for Femoral Neck Fracture Based on Postoperative Functional Status
The goal of this clinical trial is to learn whether the surgical approach used for hemiarthroplasty can improve clinical and functional outcomes in adults with displaced femoral neck fractures.
- Trial name
- NCT07501741
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Sagittal and Parasagittal Palatal Fracture
EFFICACY OF TRANSMUCOSAL MINIPLEITE STABILIZATION TECHNIQUE VERSUS INTRA-ARCH WIRE STABILIZATION TECHNIQUE FOR FIXATION OF SAGITTAL & PARA-SAGITTAL TYPES OF PALATAL FRACTURES IN TERMS OF INTRA-ARCH MOLAR DISTANCE & MAXILLO-MANDIBULAR MOLAR RELATION
The purpose of this study is to reduce uncertainity around decision making regarding use of transmucosal miniplate stabilization technique in place of intra-arch wire stabilization technique to get better outcomes.
- Trial name
- NCT07274319
- Testing
- intra arch wire stabilization technique, Transmucosal Miniplate Stabilization
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Tibial Fracture, Fracture of the Tibia Type AO/OTA 42
Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures
Approximately 1000 patients presenting with tibial shaft fractures (AO type 42) will be enrolled prospectively in this registry.
- Trial name
- FROST (NCT03598530)
- Testing
- Surgery
- Where
- 15 sites in United States, Belgium and 7 more
- Volunteers
- 1,000 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Pilon Fracture
Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
High energy intra-articular fractures of the distal tibia, or Pilon fracture, is a devastating injury with multiple short and long term complications.
- Trial name
- NCT03652753
- Testing
- N-acetylcysteine, Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Missouri-Columbia
Hip Fracture, Hip Fracture Surgeries
External Validation of Ten Prediction Models for 30-day Mortality Following Hip Fracture
This study aims to externally validate ten existing prediction models with a low risk of bias for 30-day mortality following hip fracture.
- Trial name
- PROTECT (NCT06961253)
- Where
- Netherlands
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- JointResearch
Calcaneus Fracture
Osteosynthesis of Intraarticular Calcaneal Fractures: Arthroscopically Assisted Percutaneous Technique Versus Sinus Tarsi Approach
In this randomized controlled trial, the outcomes of two surgical techniques for intraarticular calcaneal fractures will be evaluated and compared.
- Trial name
- NCT04372251
- Testing
- Sinus tarsi approach (STA), Percutaneous Arthroscopically Assisted Osteosynthesis (PACO)
- Where
- 5 sites in Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold Hospital Trust
Hip Fractures
Rehabilitation After a Hip Fracture: the Effects of Dietary Protein and Exercise on Bone and Muscle Health and Quality of Life
Hip fractures often lead to functional limitations, loss of independence, weight loss and decreased well-being. Only half of the patients regain their functional level and 24% die within the following year.
- Trial name
- ProBUS (NCT07036341)
- Testing
- Protein-enriched diet, Progressive resistance exercise
- Where
- 2 sites in Netherlands
- Volunteers
- 102 people
- Sponsor
- Wageningen University
Pseudarthrosis, Clavicle Fracture
Descriptive Single-center Retrospective Study of a Series of Cases of Clavicle Pseudarthrosis: Epidemiology, Surgical Management, and Functional Outcomes
1. Study identification Study title: PSEUDO-CLAV - Single-center retrospective descriptive study of clavicle nonunion (pseudarthrosis): epidemiology, surgical management, and functional outcomes PSEUDO-clav_Notice non oppositi……
- Conditions
- Pseudarthrosis, Clavicle Fracture, Clavicle Fracture, Non Union/Malunion
- Trial name
- PSEUDO-CLAV (NCT07414654)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Rib Fracture Multiple, Flail Chest
Surgery for Unstable Chest Wall Injuries - How Many Fractures Should be Fixed?
The goal of this prospective, randomized study is to learn about the effects of two different surgical techniques for treating unstable chest wall injuries in adults.
- Trial name
- NCT07338656
- Testing
- Surgical stabilization of two fractures per rib, Surgical stabilization of one fracture per rib.
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Primary Osteoarthritis, Secondary Osteoarthritis
Clinical and Radiological Outcomes of Medacta Shoulder System FR
This is a post-marketing surveillance on Medacta Shoulder System
- Conditions
- Primary Osteoarthritis, Secondary Osteoarthritis, Rotator Cuff Tear Arthropathy, Rheumatoid Arthritis Shoulder
- Trial name
- NCT05926622
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Medacta International SA
Fracture, Erosion
Evaluation of the Diagnostic Potential of Nanox.ARC Tomosynthesis System for Different Diseases
This is a prospective, single-arm, clinical study evaluating the diagnostic performance of the Nanox.ARC Digital Tomosynthesis (DTS) system in adult patients with suspected or confirmed musculoskeletal (MSK) pathologies…
- Trial name
- Nan-05 (NCT07900412)
- Testing
- Nanox.ARC Digital Tomosynthesis System
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Nano-X Imaging
Hand Surgery, Wrist Surgery
The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery
Patients undergoing hand, wrist, and elbow surgery may experience pain after surgery. The orthopedic surgeon may provide prescription pain medications after surgery to assist with pain control.
- Conditions
- Hand Surgery, Wrist Surgery, Elbow Surgery, Fracture Fixation
- Trial name
- NCT06806410
- Testing
- Liposomal bupivacaine (LB), Dexamethasone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Vertebral Fracture, Osteoporosis
Effectiveness of Implementation of Opportunistic AI-screening for Vertebral Fractures in Clinical Practice
The aim of this study is to evaluate clinical effectiveness and cost-effectiveness after implementing a medically approved and commercially available AI support system for opportunistic vertebral fracture screening in CT…
- Trial name
- vertAIdo (NCT07100756)
- Testing
- AI vertebral fracture diagnostics (Flamingo)
- Where
- Sweden
- Volunteers
- 10,500 people
- Sponsor
- University Hospital, Linkoeping
Fracture Femur, Fracture Tibia
Oral Supplementation With a Formulation Based on Cetylated Fatty Acids for Post-fracture Long Bone Healing
This clinical study aims to evaluate the potential benefits of a formulation based on Cetylated Fatty Acids in improving fracture healing of long bones in the lower limbs.
- Trial name
- CETIULTRA-BONE (NCT07299851)
- Testing
- CFA-based food supplement
- Where
- 6 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Pharmanutra S.p.a.
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.