Clinical trials: Blood Pressure Regulation
Stress, Blood Pressure
Real-Time Functional Magnetic Resonance Imaging Neurofeedback for Regulation of Psychophysiological Functions
The purpose of this study is to determine the potential efficacy of real-time functional magnetic resonance imaging neurofeedback (RT- functional magnetic resonance imaging (fMRI) -NF) in regulating brain activity and…
- Trial name
- NCT01921088
- Testing
- real-time functional magnetic resonance imaging neurofeedback (RT-fMRI-NF), Ambulatory Training
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Hypertension, Hemodialysis
Improving Blood Pressure Control in End-Stage Renal Disease Through a Supportive-Educative Nursing Intervention
The major purpose of this quantitative study is to determine if a 3 month supportive educative nursing intervention incorporating Blood Pressure (BP) education and BP, salt and fluid monitoring, in addition to goal setting and…
- Trial name
- NCT01052220
- Testing
- BP education and BP self-regulation, Supportive Educative Nursing Intervention
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- Wayne State University
Orthostatic Intolerance
Blood Pressure and Brain Blood Flow Regulation After Midodrine Administration in Those With Spinal Cord Injury
This project aims to evaluate the physiological effects of Midodrine administration during orthostatic challenge in those with high level spinal cord injury.
- Trial name
- NCT01498809
- Testing
- Midodrine
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of British Columbia
Cardiovascular Diseases, Hypertension
Insulin Resistance and Blood Pressure Regulation in Blacks
To determine the role of insulin resistance in peripheral vascular dynamics, sodium sensitivity, and blood pressure regulation in a young representative Black population and in a group of young Blacks at high risk for…
- Conditions
- Cardiovascular Diseases, Hypertension, Heart Diseases, Insulin Resistance
- Trial name
- NCT00005164
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Cardiovascular Diseases, Heart Diseases
Biobehavioral Mechanisms of Blood Pressure Regulation
To investigate the role of biobehavioral factors in the pathogenesis of concentric left ventricular hypertrophy.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension
- Trial name
- NCT00005366
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy Adult Male, Healthy Adult Females
Investigating Sex Differences in Mitochondrial Function and Leg Blood Flow During Exercise
This study will compare mitochondrial function and leg blood flow during exercise in healthy endurance-trained females and males aged 19-35.
- Trial name
- MITOP (NCT07866651)
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Salt-sensitive Hypertension
Intervention Study to Compare the Natriuretic Effects of Enalapril on Low and High Salt Diet
The kidney plays a crucial role in maintaining salt balance by two opposing physiological mechanisms: the renal dopaminergic system which enhances salt excretion and the renin-angiotensin system (RAS) which causes salt retention.
- Trial name
- Salt (NCT01324245)
- Testing
- Fenoldopam
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Hypotension, Orthostatic, Total Hip Replacement
Study on Baroreceptor Function in Relation to Orthostatic Blood Pressure Regulation After Hip Surgery
The purpose of this observational study is to evaluate the baroreceptor function in relation to surgical inflammation and orthostatic intolerance after elective hip arthroplasty.
- Trial name
- NCT01866787
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Retinal Bloodflow
Regulation of Retinal Bloodflow Pressure
Autoregulation is defined as the ability of a vascular bed to adapt its vascular resistance to changes in perfusion pressure. In the eye, several studies have reported that retinal blood flow is autoregulated over a wide range of…
- Trial name
- NCT03398616
- Where
- Austria
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Gerhard Garhofer
Healthy
Regulation of Optic Nerve Head Blood Flow During Combined Changes in Intraocular Pressure and Arterial Blood Pressure
Autoregulation is the ability of a vascular bed to maintain blood flow despite changes in perfusion pressure. The existence of an effective autoregulation in the optic nerve head (ONH) circulation has been shown in animals and…
- Trial name
- NCT00915226
- Testing
- Suction cup application, Squatting
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Gestational Hypertension
Role of the Oral Microbiome in Blood Pressure Regulation in Pregnancy
High blood pressure in pregnancy is associated with poor outcomes for both mum and baby, increasing the risk of pregnancy complications including pre-eclampsia, fetal growth restriction and preterm birth.
- Trial name
- NCT03930693
- Testing
- Beetroot juice
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Down Syndrome
Blood Flow Regulation in Individuals With Down Syndrome - Training Study
Work capacity is an important predictor of declining health or physical function, and of mortality, and is commonly measured as peak oxygen consumption.
- Trial name
- NCT04854122
- Testing
- Combined exercise intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Healthy
Effects of Peptides Derived From Fermented Milk on Blood Pressure Regulation System in Healthy Volunteers.
Several milk proteins are precursors of peptides, released during fermentation, which possess various biochemical and physiological properties.
- Trial name
- NCT00399737
- Testing
- repeated intake of fermented milk followed by a single oral dose of an ACE inhibitor
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiovascular Disease
Cardiometabolic Benefits of Omega-3 Polyunsaturated Fatty Acids
Omega 3 fatty acids have been shown to provide a number of cardiometabolic benefits in both healthy and at risk populations. Specifically, the daily consumption of fish oil supplements has been reported to reduce blood…
- Trial name
- TGIF (NCT03378232)
- Testing
- High EPA Supplement, High DHA Supplement
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Blood Pressure Regulation
The Effects of Nitrate-Rich Mouthwash on Vascular Tone
High blood pressure (hypertension) is a major risk factor for cardiovascular disease. One important contributing factor to high blood pressure is reduced availability of nitric oxide (NO).
- Trial name
- NITRATONE (NCT07602764)
- Testing
- Nitrate-rich mouth rinse, Nitrate-rich drink
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Postmenopausal Women
Effect of Beetroot Juice on Blood Pressure Regulation in Post Menopausal Women
In this study the investigators will test the hypothesis that acute consumption of inorganic nitrate (supplied in concentrated beetroot juice) reduces artery stiffness and resting blood pressure, and lessens the rise in blood…
- Trial name
- NCT03380000
- Testing
- Beetroot juice
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Penn State University
Hypertension
Effect of Exercise and Diet on Inflammation in Hypertensive Individuals
In addition to high blood pressure, hypertension is characterized by inflammation, which is the body's response to injury or infection. Inflammation has been found to cause plaque formation on artery walls.
- Trial name
- NCT00338572
- Testing
- Exercise Program, Combined Exercise and Diet Program
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- University of California, San Diego
Obesity (Disorder), Weight Change
Impact of Semaglutide Withdrawal on Cardiometabolic Profile and Physiology of Energy Balance: Recovery Effects After Semaglutide Termination
Semaglutide is a medication from the class of drugs called glucagon-like peptide-1 agonists that promote weight loss. There is little clinical data on the best strategy to achieve weight maintenance following weight reduction…
- Conditions
- Obesity (Disorder), Weight Change, Blood Pressure Monitoring, Appetite Regulation
- Trial name
- REST (NCT07294950)
- Testing
- Gradual dose reduction of semaglutide, Abrupt cessation of semaglutide
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Mount Sinai Hospital, Canada
Blood Pressure, Hypertension
Blood Pressure Regulation - Role of Potassium
Project titel: Oral potassium supplementation in healthy men - interactions with the renin-angiotensin-aldosterone system and the sympathetic nervous system Protocol number: KARAASS-1 EudraCT number: 2013-004460-66 Introduction…
- Trial name
- NCT02380157
- Testing
- Kaleorid, 750mg (trade name), Potassium chloride (active substance)
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen