Clinical trials: Blood Pressure Control
Dynamic Strength Exercise Session, Isometric Strength Exercise Session
Acute and Chronic Effects of Combined Training on BP in Hypertensives
Dynamic strength training (DST) is widely recognized for promoting neuromuscular adaptations such as increased strength and hypertrophy.
- Conditions
- Dynamic Strength Exercise Session, Isometric Strength Exercise Session, Combined Exercise Session, Control Session (CON)
- Trial name
- COMBAT-H (NCT07470450)
- Testing
- Combined strength training, Dynamic strength training, Acute Isometric Exercise Session.
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Rio Grande do Sul
Stage 1 Hypertension
Bioactive Milk Peptides and Blood Pressure
The purpose of this study is to investigate the effects of bioactive milk peptides on blood pressure in mildly hypertensive subjects.
- Trial name
- NCT01031485
- Testing
- Milk peptides and plant sterols
- Where
- Finland
- Sponsor
- Valio Ltd
Hypertension (HTN), Ischemic Heart Disease
Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE)
We investigated whether video-based education using deepfake technology could improve blood pressure measurement adherence and medication adherence in patients with ischemic heart disease accompanied by hypertension.
- Trial name
- V-EDUCATE (NCT07210073)
- Testing
- Video Education, Control
- Where
- South Korea
- Volunteers
- 218 people
- Sponsor
- Keimyung University Dongsan Medical Center
Hypertension
Efficacy of Chlorthalidone and Hydrochlorothiazide Combined With Amiloride on Blood Pressure in Primary Hypertension.
Thiazide diuretics have demonstrated favorable blood pressure lowering efficacy, safety profile and low cost, but it is still unclear what are the equivalence of doses of their more common agents, chlorthalidone and…
- Trial name
- NCT03928145
- Testing
- Chlorthalidone 25 mg, Hydrochlorothiazide 50 mg, Amiloride 20 mg
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension
Controlling and Lowering Blood Pressure With The MOBIUSHD™
To evaluate the safety and performance of the MobiusHD system in subjects with resistant hypertension.
- Trial name
- CALM-FIM_US (NCT01831895)
- Testing
- MobiusHD™
- Where
- 7 sites in United States
- Volunteers
- 17 people
- Sponsor
- Vascular Dynamics, Inc.
Obstructive Sleep Apnea Syndrome, Resistant Hypertension
Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome
The aim is to evaluate the effect of treatment with Continuous Positive Airway Pressure (CPAP) device on clinic and ambulatory blood pressures (BP) of 200 resistant hypertensive patients with moderate-severe obstructive sleep…
- Trial name
- NCT01508754
- Testing
- Continuous positive airway pressure treatment
- Where
- Brazil
- Volunteers
- 125 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Primary Aldosteronism
Intensive vs. Standard Blood Pressure Control in Primary Aldosteronism
The goal of this clinical trial is to evaluate whether an intensive blood pressure control strategy (systolic blood pressure target <120 mmHg) is more effective than a standard strategy (systolic blood pressure target <140 mmHg)…
- Trial name
- Intensia-Aldo (NCT07673445)
- Testing
- Intensive BP control, Standard BP control
- Where
- China
- Volunteers
- 3,830 people
- Sponsor
- Chongqing Medical University
Hypertension
Salt Intake and Blood Pressure Control in Adults With Essential Hypertension
The goal of this study is to explore the barriers and facilitators to adopting a reduced dietary salt and increased potassium intake among adults with essential hypertension in Singapore, and to evaluate the feasibility and…
- Trial name
- NCT07025928
- Testing
- Decreased Salt High Potassium Tool (DSHP Tool)
- Where
- Singapore
- Volunteers
- 190 people
- Sponsor
- Sun Jingfeng
Hemodialysis Patients
Reducing Dialysate Sodium Effect on Blood Pressure Variability in Hemodialysis Patients
In this study the investigators aim to test the effect of lowering dialysate sodium concentration on visit-to-visit blood pressure variability in hemodialysis patients who have achieved their dry weight.
- Trial name
- NCT05169125
- Testing
- standard hemodialysis, lower dialysate sodium dialysis
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Uncontrolled Hypertension, Resistant Hypertension
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
This is a Phase III, multicentre, randomised, double-blinded, placebo-controlled, parallel group study to evaluate the safety, tolerability and effect of 1 or 2 mg baxdrostat versus placebo, administered once daily (QD) orally…
- Trial name
- BaxHTN (NCT06034743)
- Testing
- Baxdrostat
- Where
- 263 sites in United States, Argentina and 27 more
- Volunteers
- 796 people
- Sponsor
- AstraZeneca
Hypertension
The Effect of Pharmacist Intervention on Blood Pressure Control
The purpose of the study is to test if a Pharmacist Intervention Program with home blood pressure monitoring (HBPM) improves or controls pharmacological adherence and blood pressure levels in hypertensive patients under…
- Trial name
- AFenPA (NCT01233193)
- Testing
- Health education, Home blood pressure monitoring
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Universidad de Granada
Symptomatic Neurogenic Orthostatic Hypotension
Clinical Effect of Ampreloxetine (TD-9855) for Treating Symptomatic nOH in Subjects With Primary Autonomic Failure
A Phase 3 study to evaluate efficacy, safety, and tolerability of ampreloxetine (TD-9855) in subjects with primary autonomic failures (MSA, PD, or PAF) and symptomatic nOH with up to 4 weeks of treatment.
- Trial name
- SEQUOIA (NCT03750552)
- Testing
- ampreloxetine
- Where
- 125 sites in United States, Australia and 17 more
- Volunteers
- 195 people
- Sponsor
- Theravance Biopharma
Total Laparoscopic Hysterectomy
Acupuncture for Blood Pressure Fluctuation During Total Laparoscopic Hysterectomy
The goal of this pilot clinical trial is to learn about efficacy of acupuncture about blood pressure fluctuation during total laparoscopic hysterectomy in patients with uterine fibroid.
- Trial name
- ASBP (NCT05720884)
- Testing
- acupuncture
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Ilsan Cha hospital
Diabetes Type 2
Effects of Pomegranate Juice on Oxidative Stress in Patients With type2 Diabetes
Introduction: Diabetes mellitus a chronic diseases, is the most common and important metabolic disease in human. Increased free radicals production due to hyperglycemia produces oxidative stress which worsens the disease and its…
- Trial name
- NCT02559843
- Testing
- pomegranate juice, lifestyle modification
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- National Nutrition and Food Technology Institute
Critical Illness, Physiological Stress
Trial to Evaluate the Effects of Sound Modulation on Critically Ill Patients
The goal of the project is to determine the effects of noise masking and noise reduction on stress related physiological parameters in critically ill patients admitted to the intensive care unit.
- Conditions
- Critical Illness, Physiological Stress, Delirium, Sleep Deprivation
- Trial name
- SMART (NCT03019133)
- Testing
- Sound reduction, Sound masking
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brian Gehlbach
Positive Emotions, Blood Pressure
The Impact of a Gratitude Intervention on Stress Reactivity
This study will employ a randomized mixed between-within experimental stress-testing protocol design. Physiological responses (blood pressure and pulse) will be recorded throughout a baseline, gratitude induction, standard…
- Conditions
- Positive Emotions, Blood Pressure, Stress, Psychological
- Trial name
- NCT05133063
- Testing
- Gratitude letter, Control intervention
- Where
- Ireland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Maynooth
Hypertensiona, Menopause
EFFECTS of BEETROOT JUICE INTAKE and PHYSICAL EXERCISE in POSTMENOPAUSAL HYPERTENSIVE WOMEN
The goal of this clinical trial is to verify the hemodynamic and biomarker responses of aerobic physical exercise and beetroot juice intake in postmenopausal women with hypertension.
- Trial name
- EBJPEPHW (NCT06585904)
- Testing
- 1 dose of Beetroot juice intake, Exercise
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Federal University of Uberlandia
Type 2 Diabetes, Coronary Artery Disease
Intensive Blood Pressure and LDL Lowering in Diabetic Patients With Coronary Artery Disease
The purpose of this study is to determine whether intensive blood pressure and low density lipoprotein (LDL) cholesterol lowering could improve survival and cardiovascular outcome in Japanese diabetic patients with coronary…
- Conditions
- Type 2 Diabetes, Coronary Artery Disease, Hypertension, Dyslipidemia
- Trial name
- NCT01422421
- Testing
- intensive control, standard control
- Where
- 2 sites in Japan
- Volunteers
- 798 people
- Sponsor
- Takeshi Morimoto
Postpartum Hypertension (PPHT)
PEACE Trial: Postpartum Evaluation of Antihypertensive Cessation and Efficacy
This randomized controlled trial compares two common medications, labetalol and extended-release nifedipine, to determine which is more effective at managing postpartum high blood pressure.
- Trial name
- PEACE (NCT06915792)
- Testing
- Labetalol, Nifedipine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Los Angeles
Coronary Artery Disease
Vericiguat Drug-drug Interaction With Nitroglycerin in Stable Coronary Artery Disease Patients
This study is intended to investigate the effect of nitroglycerin on vericiguat in patients with stable coronary artery disease (CAD). Nitroglycerin is the standard therapy to treat acute crisis of angina.
- Trial name
- VENICE (NCT02617550)
- Testing
- Vericiguat (BAY1021189), Nitroglycerin
- Where
- 6 sites in Germany
- Volunteers
- 36 people
- Sponsor
- Bayer