Clinical trials: Bleeding Ugi
Upper GI Bleeding
Clinical Risk Scores in Prediction Outcome of Acute UGIT Bleeding in Non Cirrhotic Patients
To compare the ability of 4 bleeding risk scoring systems (Glasgow -Blatchford score, MAP, H3B2 and ABC scores ) in prediction of: Need of intervention, Re bleeding, Thirty-day mortality, length of hospital stay
- Trial name
- NCT06254352
- Testing
- scoring system
- Volunteers
- 100 people
- Sponsor
- Assiut University
Upper Gastrointestinal Bleeding, Peptic Ulcer Hemorrhage
Anticoagulation With Enhanced Gastrointestinal Safety
This study is a pragmatic cluster randomized controlled trial to evaluate the effectiveness of a clinician-facing implementation strategy on the use of medication optimization (defined as either discontinuation of all…
- Conditions
- Upper Gastrointestinal Bleeding, Peptic Ulcer Hemorrhage, Anticoagulant-induced Bleeding
- Trial name
- AEGIS (NCT05563714)
- Testing
- Clinician Notification with Nurse Facilitation (CNNF), Wait list control
- Where
- United States
- Volunteers
- 341 people
- Sponsor
- University of Michigan
Peptic Ulcer Hemorrhage
The Dissemination of Consensus Recommendations on Upper Gastrointestinal Bleeding
The purpose of this study is to assess whether adherence to NVUGIB guidelines is improved with implementation of a national, tailored multifaceted intervention.
- Trial name
- REASON-II (NCT00840008)
- Testing
- Educational intervention
- Volunteers
- 3,157 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Congenital Heart Disease, Upper Gastrointestinal Bleeding
Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease
Infants with congenital heart disease often require an intervention during their first year of life. Infants are generally admitted to a cardiac intensive care unit and are routinely prescribed stress ulcer prophylaxis to…
- Conditions
- Congenital Heart Disease, Upper Gastrointestinal Bleeding, Stress Ulcer, Infection
- Trial name
- SUPPRESS-CHD (NCT03667703)
- Testing
- Famotidine
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Bleeding UGI (During or Post-ERCP)
Incidence and Predictors of Bleeding During and Following ERCP
The incidence of bleeding during ERCP and following ERCP has been estimated using retrospective sources, but granular predictors of bleeding remain unknown, including the use of direct-acting anticoagulants and discontinuation…
- Trial name
- NCT05929404
- Where
- Canada
- Volunteers
- 5,872 people
- Sponsor
- University of Calgary
Cirrhosis, Liver, Upper Gastrointestinal Bleeding
Terlipression Prevent Developing of Acute Kidney Injury During Upper-gastroentestinal Bleeding
The investigators studied the renal function index level in terlipressin treated cirrhotic patients with upper-gastrointestinal bleeding at different time point.
- Trial name
- NCT04358016
- Testing
- Terlipressin, Somatostatin
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Changhai Hospital
Upper Gastrointestinal Bleeding (UGIB), High Risk Bleeding
A New Scoring System to Predict High-Risk Groups in Upper Gastrointestinal Bleeding
Upper gastrointestinal bleeding (UGIB) remains a common and potentially life-threatening emergency condition requiring early risk stratification to guide clinical management.
- Trial name
- UGIS (NCT07458178)
- Where
- Turkey (Türkiye)
- Volunteers
- 312 people
- Sponsor
- Izmir Katip Celebi University
Stress Ulcer Prophylaxis
Stress Ulcer Prophylaxis of Intravenous Esomeprazole in Chinese Seriously Ill Patients
The efficacy of esomeprazole will be compared versus cimetidine (a drug that previously demonstrated prevention of bleeding events) during treatment period in proportion of patients for the prevention of upper GI bleeding.
- Trial name
- SUP (NCT02157376)
- Testing
- Esomeprazole, Cimetidine
- Where
- 15 sites in China
- Volunteers
- 343 people
- Sponsor
- AstraZeneca
Gastrointestinal Hemorrhage, Gastrointestinal Neoplasms
Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions
This study evaluates the efficacy of the endoscopic hemostatic powder for the treatment of bleeding from malignant lesions of the upper GI tract.
- Trial name
- NCT02820077
- Testing
- Hemospray (Endoscopic treatment with hemostatic powder)
- Volunteers
- 62 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Carbon Footprint in Upper GI Endoscopy, Dyspepsia
The Difference in Carbon Footprint Between Diagnostic Upper GI Endoscopy in Dyspeptic Patients Versus Therapeutic Upper GI Bleeding
The goal of this observational study is to learn about the carbon footprint produced from diagnostic upper GI endoscopy in patients with dyspepsia and therapeutic upper GI endoscopy in patients with non-variceal upper GI…
- Conditions
- Carbon Footprint in Upper GI Endoscopy, Dyspepsia, Non-variceal Upper Gastrointestinal Bleeding
- Trial name
- NCT07261228
- Where
- 2 sites in Thailand
- Volunteers
- 75 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Upper GI Bleeding, Bleeds Gastric
Metoclopramide in Upper Gastrointestinal Bleed
The goal of this clinical trial is to test if metoclopramide can improve effectiveness of endoscopic intervention in upper gastrointestinal (GI) bleeds.
- Conditions
- Upper GI Bleeding, Bleeds Gastric, Bleed Ulcer, Hemorrhage Gastric
- Trial name
- NCT05746377
- Testing
- Metoclopramide 10mg, Saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mercy Health System
Esophageal Varices
Upper Endoscopy in Cirrhotic Patients With Upper Gastrointestinal Bleeding
Liver cirrhosis is a common diffuse and persistent liver disease often accompanied by portal hypertension, liver failure, upper gastrointestinal bleeding (UGIB), and other complications.
- Trial name
- Varices (NCT06214234)
- Testing
- Band ligation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cirrhosis, Varices, Esophageal
Probiotics for Portal Hypertension
Chronic peripheral and splanchnic vasodilatation are the hallmark hemodynamic abnormality in cirrhosis and contribute to the pathogenesis of portal hypertension.
- Trial name
- NCT01134692
- Testing
- Propranolol, Norfloxacin, VSL#3
- Where
- India
- Sponsor
- Govind Ballabh Pant Hospital
Upper GI Bleeding
Detection of Upper Gastrointestinal (GI) Bleeding With a Novel Bleeding Sensor Capsule [DING]
The clinical trial entitled "Detection of upper gastrointestinal (GI) bleeding with a novel bleeding sensor capsule - a pilot study" was carried out in a monocentric clinical trial with 30 patients.
- Trial name
- DING (NCT03176407)
- Testing
- HemoPill acute
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ovesco Endoscopy AG
Upper Gastrointestinal Bleeding
Awareness of Iron Status Evaluation in UGIB
BACKGROUND: Data on the awareness of the need to evaluate iron status and IDA prevalence in acute UGIB are limited. OBJECTIVES: This study aimed to investigate the rate of evaluation of iron status and prevalence of iron…
- Trial name
- AISE (NCT06299007)
- Where
- Thailand
- Volunteers
- 867 people
- Sponsor
- Hat Yai Medical Education Center
Peptic Ulcer Hemorrhage, Peptic Ulcer, Acute With Hemorrhage
Registry for Upper Gastrointestinal Bleeding
This project aims to evaluate the data on all patients undergoing endoscopic therapy for upper gastrointestinal bleeding.
- Trial name
- NCT04211194
- Testing
- Upper GI Endoscopy
- Where
- United States
- Volunteers
- 2,999 people
- Sponsor
- AdventHealth
Gastrointestinal Hemorrhage
Predictive Role of Red Cell Distribution Width in Upper GI Bleeding Patients
Acute upper-gastrointestinal bleeding (UGIB) is a commonly encountered cause of admission in emergency department (ED). Early risk stratification allows appropriate therapy that may be helpful to advance the patient's morbidity…
- Trial name
- NCT03119987
- Testing
- Red cell distribution widths
- Volunteers
- 400 people
- Sponsor
- Konkuk University Medical Center
Gastrointestinal Bleeding
Efficacy of a Novel Hemostatic Powder in GI Bleeding
Hemospray™ is a new endoscopic hemostatic powder. Aims of this multicenter prospective study is to determine effectiveness of Hemospray™ on short and medium term in different clinical situations, predictive factors of rebleeding…
- Trial name
- GRAPHE (NCT02595853)
- Testing
- Non interventional study
- Where
- 19 sites in France, Monaco
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
UGI Bleeding, Ulcer or Variceal Hemorrhage
Doppler Ultrasound Probe for Blood Flow Detection in Severe Upper Gastrointestinal Hemorrhage
The main purposes of this study are to compare clinical outcomes of two groups of patients with similar medical conditions (one with non-variceal upper gastrointestinal (UGI) lesions such as ulcers and another group with varices…
- Conditions
- UGI Bleeding, Ulcer or Variceal Hemorrhage, Stigmata of Recent Hemorrhage, Endoscopy
- Trial name
- NCT00732212
- Testing
- Doppler endoscopic ultrasound probe for blood flow detection, Standard endoscopic hemostasis
- Where
- 2 sites in United States
- Volunteers
- 235 people
- Sponsor
- VA Office of Research and Development
Upper Gastrointestinal Bleeding, Acute Kidney Injury
Acute Kidney Injury in Upper GI Bleeding Patients
This study aims to evaluate the incidence of acute kidney injury (AKI) among patients presenting with acute upper gastrointestinal bleeding (UGIB) at Sohag University Hospitals, and to identify predictors associated with renal…
- Trial name
- NCT07636083
- Testing
- Observational assessment
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University