Clinical trials: Bladder Injury
Vesico-ureteral Reflux, Spinal Cord Injury
Reflux in Spinal Cord Injury Patients With Neurogenic Lower Urinary Tract Dysfunction
The purpose of this study is to investigate the incidence of reflux in patients with spinal cord injury in relation to the lesion level, duration of injury and bladder management
- Trial name
- NCT01297673
- Testing
- video-urodynamic examination
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Balgrist University Hospital
Spinal Cord Injury, Neurogenic Bladder
The Effects Upon the Bladder of Transcutaneous Tibial Nerve Stimulation in Acute Traumatic Spinal Cord Injury
The purpose of this research study is to evaluate the effects upon the bladder of electric stimulation of the leg's tibial nerve in people with acute spinal cord injury with an intervention called transcutaneous tibial nerve…
- Trial name
- NCT02573402
- Testing
- Transcutaneous Tibial Nerve Stimulation, Control
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The University of Texas Health Science Center, Houston
Prostate Cancer, Radiotherapy Side Effect
Less to Hold - A Comparison of Bladder Toxicities (Side Effects) in Patients Undergoing Prostate Radiotherapy Between Patients Treated With Empty Bladder and Those on a Drinking Protocol.
Radical radiotherapy to the prostate is conventionally treated with a full bladder with the aim of minimising dose to the bladder and small bowel to prevent significant side effects.
- Trial name
- NCT03832803
- Testing
- Empty bladder, Full bladder
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Overactive Bladder
A Long-term Follow-up Study of Botulinum Toxin Type A in Patients With Overactive Bladder as a Result of Spinal Injury or Multiple Sclerosis
The purpose of this study is to assess the long-term safety and effectiveness of botulinum toxin type A on patients with overactive bladder as a result of spinal cord injury or multiple sclerosis.
- Trial name
- NCT00876447
- Testing
- Botulinum Toxin Type A 300U, Botulinum Toxin Type A 200U
- Where
- 22 sites in United States, Australia and 20 more
- Volunteers
- 397 people
- Sponsor
- Allergan
Spinal Cord Injuries (SCI), Detrusor Overactivity
The Effectiveness of Transcutaneous Sacral Neuromodulation Techniques-Magnetic Stimulation and Electrical Stimulation-on Detrusor Overactivity in Patients With Spinal Cord Injury
The goal of this prospective, randomized clinical trial is to compare the efficacy and safety of transcutaneous sacral magnetic stimulation versus sacral electrical stimulation for detrusor overactivity in 40 male and female…
- Trial name
- NCT07578532
- Testing
- Transcutaneous Sacral Electrical Stimulation, Transcutaneous sacral magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Ureteral Stent Occlusion, Exposure Laser
Recovery Following Desflurane Versus Sevoflurane for Outpatient Urologic Surgery in Elderly Females
Numerous studies demonstrate that patients have improved immediate recovery characteristics following desflurane anesthesia compared to other volatile agents, including sevoflurane.
- Conditions
- Ureteral Stent Occlusion, Exposure Laser, Ureterostomy; Functional Disturbance, Vaginal Diseases
- Trial name
- NCT01310582
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hahnemann University Hospital
Vaginal Fistula, Vesico Vaginal Fistula
Feasibility of the Menstrual Cup for VVF
This study examines the feasibility and acceptability of the vaginal menstrual cup for short-term management of vesicovaginal fistula (VVF) among 11 women seeking treatment at a health facility in Ghana.
- Conditions
- Vaginal Fistula, Vesico Vaginal Fistula, Obstetric; Injury
- Trial name
- FMCVVF (NCT03414060)
- Testing
- Menstrual Cup
- Where
- Ghana
- Volunteers
- 11 people
- Sponsor
- University of Ghana Medical School
Urinary Bladder Neurogenic Dysfunction
Neuro-urological Outcome After Spinal Cord Injury
Most patients with spinal cord injury suffer from bladder dysfunction which may - especially in the long-term - impair renal function. Improved treatment during the last decades improved life expectancy and quality of life.
- Trial name
- NCT01297660
- Testing
- Video-urodynamic examination
- Where
- Switzerland
- Volunteers
- 55 people
- Sponsor
- Balgrist University Hospital
Urinary Bladder, Neurogenic
Ambulatory Closed-loop Stimulation for Bladder Control
Individuals with spinal cord injury (SCI) develop neurogenic detrusor overactivity (NDO), resulting in urinary incontinence, decreased bladder capacity, and reduced quality of life.
- Trial name
- NCT05740527
- Testing
- Noninvasive electrical stimulation of genital nerves
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- MetroHealth Medical Center
Spinal Cord Injuries, Multiple Sclerosis
GentleCath Air (Urinary Self-catheterization) - Pain in Female Patients With Neurological Vesico-sphincter Disorders
The purpose of this study is to evaluate the rate of occurrence of urethral pain in female patients with neurological vesico-sphincter disorders whilst performing self-catheterization using GentleCath™ Air catheters.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Parkinsonian Disorders, Allodynia
- Trial name
- FollowAir (NCT04847609)
- Testing
- GentleCath™ Air catheter
- Sponsor
- ConvaTec Inc.
Spinal Cord Injury
Electrical Control of Bladder in Spinal Cord Injury Patients
The investigators will continue their work with implanted stimulators to improve bladder and bowel function. Electrical stimulation produces simultaneous contraction of sphincters with the target organs, making emptying…
- Trial name
- NCT00011570
- Testing
- Bladder & Bowel Control
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injury, Acute, Neurogenic Bladder
Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury
The purpose of this study is to see what effects sacral neuromodulation has on bladder function and quality of life in patients with acute spinal cord injury.
- Conditions
- Spinal Cord Injury, Acute, Neurogenic Bladder, Incontinence, Urinary Tract Infections
- Trial name
- NCT03083366
- Testing
- PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Urinary Bladder, Neurogenic, Blood Pressure
Recovery of Bladder and Sexual Function After Human Spinal Cord Injury
This study will incorporate critical cross viscero-visceral intersystem interactions to 1) investigate in a controlled laboratory setting and then with mobile at-home monitoring the extent, severity, and frequency of occurrence…
- Conditions
- Urinary Bladder, Neurogenic, Blood Pressure, Autonomic Dysreflexia, Bowel Incontinence
- Trial name
- NCT04193709
- Testing
- Spinal Cord Epidural Stimulation
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Louisville
Wounds
Cytal® Wound Matrix and MicroMatrix® Wound Study
This is an observational study to assess the safety and efficacy of MicroMatrix® alone or in combination with Cytal® Wound Matrix on primary measures of wound healing.
- Trial name
- NCT03632954
- Testing
- ACell Arm
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Integra LifeSciences Corporation
Neurogenic Bladder, Spinal Cord Injuries
Gentamicin Bladder Instillation in Individuals With Spinal Cord Injury Having Chronic Urinary Tract Infections
Participants will undergo daily gentamicin bladder instillations to determine if its use will reduce the rate of symptomatic urinary tract infections (UTIs) as well as the use of oral and intravenous antibiotics in adults with…
- Trial name
- NCT03931408
- Testing
- Gentamicin Sulfate, No instillation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Louisville
Radiation-Induced Bladder Injury
Study on Biomarkers of Radiation-Induced Bladder Injury
1. To identify biomarkers of radiation-induced bladder injury; 2. To develop a predictive model for radiation-induced bladder injury.
- Trial name
- NCT07528313
- Volunteers
- 220 people
- Sponsor
- Tongji Hospital
Oncology, Breast Cancer
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further…
- Conditions
- Oncology, Breast Cancer, Prostate Cancer, Gynecologic Cancer
- Trial name
- MOMENTUM (NCT04075305)
- Testing
- Radiation therapy
- Where
- 18 sites in United States, Australia and 7 more
- Volunteers
- 8,000 people
- Sponsor
- UMC Utrecht
Spinal Cord Injury
Improving Bladder Function in SCI by Neuromodulation
This trial will investigate the safety and utility of spinal cord neuromodulation to improve urinary bladder function in the context of spinal cord injury.
- Trial name
- NCT02331979
- Testing
- Electromagnetic Neuromodulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Los Angeles
Spinal Cord Injuries
SPARC Bladder Mapping and Training Study
The investigators propose to determine the electrode configurations that promote functional gains in the storage and voiding phases of lower urinary tract function as a result of activation of spinal circuits with spinal cord…
- Trial name
- NCT03452007
- Testing
- Epidural Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or recommended dose for expansion (RDE) of intratumoral…
- Conditions
- Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Lymphoma, Non-Hodgkin
- Trial name
- ON-5001 (NCT06022029)
- Testing
- ONM-501, Cemiplimab
- Where
- 16 sites in United States, Australia
- Volunteers
- 168 people
- Sponsor
- OncoNano Medicine, Inc.