Clinical trials: Bladder Dysfunction
Neurogenic Bladder Disorder
Predictive Urodynamic Parameters for The Treatment Efficacy of Onabotulinum A Toxin in Neurogenic Lower Urinary Tract Dysfunction
Purpose: To evaluate urodynamic parameters predicting the treatment efficacy of onabotulinumtoxin A (onaBoNT-A) in patients with neurogenic lower urinary tract dysfunction (NLUTD).
- Trial name
- NCT06485453
- Testing
- Botox 200 UNT Injection
- Volunteers
- 74 people
- Sponsor
- University of Gaziantep
Bladder Tumor, Postoperative Cognitive Dysfunction
The Assessment of POCD After TURBT Under Spinal Anesthesia
This study evaluates the influence of premedication on cognitive functions in patients undergoing transurethral resection of bladder tumor under spinal anesthesia.
- Trial name
- NCT03029676
- Testing
- benzodiazepines, opioid, spinal anesthesia
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Warsaw
Bladder Dysfunction, Spinal Cord Injuries
Restoration of Bladder Function in Spinal Cord Injury
The aim of this study is to develop improved methods of restoring function to the neurogenic bladder, using electrical stimulation without cutting nerves in patients with spinal cord injury.
- Trial name
- NCT05968352
- Testing
- Sacral Anterior Root Stimulation (SARS)
- Where
- United Kingdom
- Sponsor
- University of Oxford
Overactive Bladder, Mild Cognitive Impairment
A Study of Fesoterodine and Oxybutynin on Cognitive Function in Mild Cognitive Impairment
The purpose of this study is to assess the effects of fesoterodine at 4mg and 8mg doses versus a placebo and oxybutynin 5mg bid versus placebo on cognitive abilities in older people with overactive bladder and mild cognitive…
- Trial name
- NCT02240459
- Testing
- fesoterodine 4mg, Oxybutynin, fesoterodine 8mg
- Where
- Canada
- Volunteers
- 47 people
- Sponsor
- University of Alberta
Voiding Dysfunction, Children
Smart-phone Application Versus Conventional Paper for the Documentation of Voiding Dysfunction in Children
The objective of the research is to compare the written voiding diary method to the smart-phone diary, DryDawn®, which the investigators selected among several applications using specific criteria appropriate to our population.
- Trial name
- NCT06404996
- Testing
- Smart-phone Voiding Diary, Paper voiding diary
- Volunteers
- 100 people
- Sponsor
- King Abdullah International Medical Research Center
Spinal Cord Injury
Sonographic Measurement of Bladder Wall Thickness in Patients With Neurogenic Bladder Dysfunction
Video-urodynamic investigations are regarded as the current standard diagnostics for neurogenic bladder dysfunction in patients with spinal cord injury.
- Trial name
- NCT01299792
- Testing
- sonographic measurement of bladder wall thickness
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Bladder Dysfunction
Effect of Bladder Filling on Rectal Contractions During Cystometry
Increasing knowledge on rectal motility and bladder-rectum cross-talk has been published in recent years. However, whether bladder filling factors during multichannel urodynamic studies affect rectal contraction (RC) parameters…
- Trial name
- NCT05013541
- Testing
- No intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Gérard Amarenco
Voiding Dysfunction
Evaluating the Optimal Volume Voided for Passage of a Backfill-Assisted Voiding Trial Following Urogynecologic Surgery
Urinary retention can lead to bladder over-distention, ischemia, and long-term voiding dysfunction, and early identification of urinary retention can help prevent these adverse events
- Trial name
- NCT05820139
- Testing
- Control Group, Test Group
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
Healthy, Nonneurogenic Neurogenic Bladder Dysfunction
Study of Electroencephalogram (EEG) Measurement During Different Stimulations of the Lower Urinary Tract
The purpose of this study is to investigate afferent and cortical activities during bladder filling under different stimulations of the lower urinary tract.
- Conditions
- Healthy, Nonneurogenic Neurogenic Bladder Dysfunction, Neurogenic Bladder Dysfunction Nos
- Trial name
- NCT01389921
- Testing
- Electroencephalography
- Where
- Switzerland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ulrich Mehnert
Urinary Retention, Urinary Bladder, Neurogenic
A Prospective Evaluation of the Catheter Science C3 "Umbrella Catheter."
The Catheter Science C3 "Umbrella Catheter" has been developed for management of urinary retention in patients who are either using a Foley or Self Intermittent Catheter.
- Conditions
- Urinary Retention, Urinary Bladder, Neurogenic, Intermittent Catheterization
- Trial name
- NCT03353571
- Testing
- C3 "UMBRELLA CATHETER"
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr. Gaines W. Hammond Jr. MD FACS
Advanced Urothelial Carcinoma, Locally Advanced Urothelial Carcinoma
Eribulin Mesylate in Treating Patients With Locally Advanced or Metastatic Cancer of the Urothelium and Kidney Dysfunction
This phase I/II trial studies the effect of eribulin mesylate and to see how well it works in treating patients with cancer of the urothelium that has spread to nearby tissue (locally advanced) or to other places in the body…
- Conditions
- Advanced Urothelial Carcinoma, Locally Advanced Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Recurrent Urothelial Carcinoma
- Trial name
- NCT00365157
- Testing
- Eribulin Mesylate, Laboratory Biomarker Analysis, Pharmacological Study
- Where
- 26 sites in United States
- Volunteers
- 168 people
- Sponsor
- National Cancer Institute (NCI)
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
Pelvic Organ Prolapse, Stress Urinary Incontinence
What is the Effect of Prolapse Surgery on Voiding?
The aim of our study is to examine the effect of prolapse surgery on voiding. Our study is the very first one to combine several innovative low-invasive and low-cost methods to analyse the amelioration or deterioration of voiding…
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Overactive Bladder, Voiding Disorders
- Trial name
- PROVOID (NCT04429360)
- Testing
- pelvic reconstructive surgery
- Where
- Belgium
- Volunteers
- 453 people
- Sponsor
- Universiteit Antwerpen
Pelvic Organ Prolapse
Restorelle® Mesh Versus Native Tissue Repair for Prolapse
The purpose of this study is to collect information on the safety and effectiveness of Restorelle Direct Fix mesh and the surgical procedure to implant Restorelle.
- Trial name
- NCT02162615
- Testing
- Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior
- Where
- 49 sites in United States, Australia and 4 more
- Volunteers
- 810 people
- Sponsor
- Coloplast A/S
Bladder and Bowel Dysfunction, Femoral Anteversion, Bladder and Bowel Dysfunction, Hip Strength Ratios
Relationship Between Pelvic Angle, Femoral Anteversion, and Hip Muscle Strength Ratios in Bladder-bowel Dysfunction
Bladder and bowel dysfunction is a combination of lower urinary tract and bowel dysfunction seen in children over 5 years of age without identifiable or discernible neurological abnormalities.
- Conditions
- Bladder and Bowel Dysfunction, Femoral Anteversion, Bladder and Bowel Dysfunction, Hip Strength Ratios, Bladder and Bowel Dysfunction, Pelvic Angle
- Trial name
- NCT05182671
- Testing
- Scales and measurements for bladder and bowel dysfunction, pelvic angle, proximal hip strength, femoral hip anteversion
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Halil Tugtepe
Uterine Cervical Neoplasms
The Role of Clean Intermittent Catheterization in Patients Undergoing Radiotherapy After Radical Hysterectomy for Cervical Cancer
Through a prospective, randomized and controlled research design method, this study implemented intermittent catheterization for patients with urinary dysfunction after postoperative radiotherapy of cervical cancer, formulated a…
- Trial name
- NCT05410444
- Testing
- Clean Intermittent Catheterization, Indwelling catheterization
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zhejiang Cancer Hospital
Urinary Dysfunction
Effects of Pelvic Floor Muscle Training Combined With Bladder Training on Some Parametrs of Men With Urinary Frequency
This prospective, single-center, parallel-group, assessor-blinded randomized controlled trial will include 120 voluntary male participants who have had complaints of urinary frequency for at least 3 months and meet the inclusion…
- Trial name
- NCT07719400
- Testing
- Bladder training plus pelvic floor muscle training, Bladder Training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bingol University
Interstitial Cystitis, Sexual Dysfunction
The Women's Urology Center/WISH Database Project
Comprehensive database from the Women's Urology Center/WISH (Women's Initiative for Pelvic Pain and Sexual Health) program at Beaumont.
- Conditions
- Interstitial Cystitis, Sexual Dysfunction, Pelvic Pain, Incontinence
- Trial name
- NCT00379002
- Where
- United States
- Volunteers
- 2,923 people
- Sponsor
- Corewell Health East
Overactive Bladder, Voiding Dysfunction
A Follow-net Investigation of a Randomised Study of Cystoscopy and Urethral Dilatation Versus Cystoscopy Alone in Women With Overactive Bladder Syndrome and Impaired Voiding
Urinary incontinences is a highly prevalent and distressing condition which has a significant impact on health related quality of life in millions of women worldwide.
- Conditions
- Overactive Bladder, Voiding Dysfunction, Urinary Incontinence
- Trial name
- NCT02297178
- Testing
- Cystoscopy only, Cystoscopy and Urethral dilatation
- Sponsor
- Medway NHS Foundation Trust
Cervical Cancer, Radical Hysterectomy
Removal of Urinary Catheter After Radical Surgery
Currently, the treatment of cervical cancer in early stages is performed with a radical surgery called Radical Hysterectomy with Pelvic Lymphadenectomy.
- Conditions
- Cervical Cancer, Radical Hysterectomy, Bladder Dysfunction
- Trial name
- NCT03570593
- Testing
- REMOVAL OF URINARY CATHETER AFTER RADICAL SURGERY
- Volunteers
- 95 people
- Sponsor
- Barretos Cancer Hospital