Clinical trials: Birth, First
Breast Pumping
Assessing the Effect of an Additional 5 Minutes Pumping on Milk Output in the First Days After Delivery
The study hypothesizes that human who are both breastfeeding and pumping in the first days postpartum have more expression volume with an additional 5 minutes of pumping with Maintain program after pumping with the INITIATE…
- Trial name
- NCT06222567
- Testing
- 15 minutes pumping with INITIATE program, 5 minutes extra pumping with MAINTAIN program
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Spinal Induced Hypotension in Cesarean Delivery
Up-Down Determination of the ED90 of Phenylephrine for Hypotension Prophylaxis in Cesarean Delivery
This study is designed to determine the ED90 for an infusion of phenylephrine to prevent spinal induced low blood pressure in parturients presenting for an elective cesarean delivery.
- Trial name
- NCT00796328
- Testing
- Phenylephrine infusion
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Cesarean Section; Dehiscence, First Birth
The Effect of Breastfeeding Pillow on Breastfeeding Self-Efficacy and Postpartum Comfort in Women Who Had Cesarean
The research is a randomised controlled experimental study. It was conducted to examine the effect of breastfeeding pillow on breastfeeding self-efficacy and postnatal comfort in primiparous puerperas who gave birth by caesarean…
- Trial name
- NCT05948150
- Testing
- using a breastfeeding pillow, not using a breastfeeding pillow
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Preterm Birth, Oxygen Toxicity
Fetal Haemoglobin and Cerebral and Peripheral Oxygenation.
The aim of this study is to investigate the relationship between cerebral and peripheral oxygenation and oxygen extraction, as measured by NIRS (near-infrared spectroscopy ), and the FHbF (fraction of fetal hemoglobin) and…
- Conditions
- Preterm Birth, Oxygen Toxicity, Fetal Hemoglobin
- Trial name
- HbFIN (NCT04802629)
- Testing
- Near-infrared spectroscopy
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Post-Partum Haemorrhage
A Clinical Trial to Study the Effectiveness of a Care Bundle to Prevent Bleeding After a Woman Has Given Birth
Every six minutes a mother dies from postpartum haemorrhage (PPH) in low-resource countries, in the prime of her life and often leaving behind a young family.
- Trial name
- E-MOTIVE (NCT04341662)
- Testing
- E-MOTIVE intervention, Usual care
- Where
- 6 sites in Kenya, Nigeria and 3 more
- Volunteers
- 99,659 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Preeclampsia, Severe Preeclampsia
First-trimester Prediction of Preeclampsia
Preeclampsia is a complication of pregnancy related to adverse maternal and neonatal outcomes, including fetal growth restriction and perinatal death.
- Conditions
- Preeclampsia, Severe Preeclampsia, Fetal Growth Restriction, Preterm Birth
- Trial name
- PREDICTION (NCT02189148)
- Where
- 4 sites in Canada
- Volunteers
- 7,554 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Birth, First, Experience, Life
The Effect of Focus on Vaginal Examination Experience and Pain Level: a Randomized Controlled Trial
Vaginal examination contains many negative emotions such as pain, fear, stress, and discomfort for women. When the literature was examined, no study was found in which the focus method was used to reduce or eliminate the feelings…
- Conditions
- Birth, First, Experience, Life, Pain
- Trial name
- NCT05471219
- Testing
- Primiparous pregnant women who will undergo vaginal examination by focusing on visual traces
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dilek Yigit Vural
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University
NO CONDITIONS
Improving Ultrasound Based Prediction of Delivery Mode
The progress of labour is traditionally determined by regular vaginal examinations (VEs) to assess the cervix (neck of the womb) and the baby's head position.
- Trial name
- NCT04635410
- Testing
- ULTRASOUND IMAGING
- Where
- United Kingdom
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Trauma
Levator Ani Muscle Avulsion at First Birth of Mexican Women: Randomized Control Trial
Levator Ani Muscle (LAM) avulsion occurs in 13-36% of women having their first birth. These damages by palpation and ultrasound of the pelvic floor can be detected.
- Trial name
- NCT02513420
- Testing
- Perineal muscle training
- Where
- Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
College Drinking
Text-based Alcohol Prevention for First Year College Students
This project aims to combat excessive perceived norms that contribute to high volume drinking by young adults, which adversely affects health and academic achievement.
- Trial name
- NCT03864237
- Testing
- Alcohol texts, Attention control
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Brown University
Childbirth, Aromatherapy
Comparison Of The Effects Of Swedish Massage With Natural Oils
Aim: This study aimed to evaluate the effects of Swedish massage combined with lavender and chamomile oils on childbirth outcomes during the first and second stages of labor.
- Conditions
- Childbirth, Aromatherapy, Pain Management, Fear
- Trial name
- Comparison (NCT07652957)
- Testing
- Aromatherapy and Massage Care for labor pain management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Labor, Pregnancy
The Effects of Warm Showers Application in Birth on Birth Pain, Birth Satisfaction and Birth Results
The use of non-pharmacological methods in labor pain is very important in order to improve the birth process, increase comfort and provide relaxation.
- Conditions
- Labor, Pregnancy, First Stage of Labor
- Trial name
- NCT05335681
- Testing
- Warm Showers Application
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Healthy Volunteers
A First-in-Human Study of the RaniPill, an Oral Drug Delivery Platform
The objective of this study is to ascertain the safety, tolerability and performance of the RaniPill capsule in healthy volunteers
- Trial name
- RaniPill (NCT03798912)
- Testing
- RaniPill capsule containing octreotide
- Where
- Australia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- RANI Therapeutics
Early-phase Safety and PK Study of a Vaginal Gel
FIH Lead-in Study of YASO GEL Followed by a Phase 1 Randomized, Double-blind Study to Assess Safety and Pharmacokinetics of YASO GEL
The goal of this clinical trial is to assess the safety and pharmacokinetics of YASO GEL in healthy adult participants. This is a first-in-human study designed to understand how the gel is absorbed and distributed in plasma and…
- Trial name
- PPCM-01 (NCT07281404)
- Testing
- YASO GEL
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yaso Therapeutics Corporation
Parturition
The Effect of Foot Bath on Birth Pain and Birth Comfort
Although childbirth is seen as a natural, happy, meaningful and universal experience, women are often faced with severe pain, discomfort and a sensory state that can be overwhelming.
- Trial name
- NCT06380400
- Testing
- Foot bath
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Contraception
A Comparison of Continuation Rates for Three Hormonal Contraceptive Methods
This study will assess the continuation rates among women using oral contraceptive pills, Depo-Provera and Ortho Evra following a first trimester abortion.
- Trial name
- NCT00253019
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Emory University
Anemia
Milking the Umbilical Cord at Term Cesarean Birth
The purpose of this pilot study is to determine if umbilical cord milking at the time of scheduled cesarean section effects the hemoglobin and hematocrit levels of full-term infants as determined by hemoglobin and hematocrit…
- Trial name
- NCT01630993
- Testing
- Umbilical Cord Milking
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Preterm and Term Infants
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study.
- Trial name
- NCT00747864
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Utah
Premature, Thermoregulation
Delaying First Bathing and Skin Barrier Function on Infant
It is still unknown when the first bath should be done in premature newborns. Investigators think that delaying the time of the first bath compared to the time in the clinic will show some positive changes in preterm newborns.
- Trial name
- TEWL (NCT04231799)
- Testing
- Bathing
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University