Clinical trials: Biomarkers
Bone Metabolism Biomarkers, Bone Mineral Density
Vitamin D and Physical Activity on Bone Health
This research will examine the effectiveness of vitamin D or placebo (the placebo is a tablet that looks like Vitamin D study drug, but has no Vitamin D study drug in it), with and without physical activity (walking and…
- Conditions
- Bone Metabolism Biomarkers, Bone Mineral Density, Physical Fitness
- Trial name
- NCT01419730
- Testing
- Vitamin D3, Physical Activity
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- University of Rochester
Age-Related Macular Degeneration, Genetic Testing
The Moran AMD Genetic Testing Assessment Study
The goals of this study are: To assess the impact of genetic testing for Age-related Macular Degeneration (AMD) on lifestyle behaviors as measured by systemic and ocular carotenoid status.
- Conditions
- Age-Related Macular Degeneration, Genetic Testing, Nutritional Biomarkers
- Trial name
- MAGENTA (NCT05265624)
- Testing
- Early disclosure of genetic testing results, Late disclosure of genetic testing results
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Paul S. Bernstein
Interaction, Endogenous Biomarkers
Pharmacokinetic Drug-Drug Interaction Study to Identify Biomarkers of Kidney Transporters
The objective of this study is to confirm the feasibility of using a panel of endogenous substrates/metabolites as a robust biomarker of OCTs and OATs by conducting a controlled, comprehensive clinical drug-drug interaction study…
- Trial name
- NCT05365451
- Testing
- MetFORMIN Oral Solution, Cimetidine 400 MG, Furosemide Oral Liquid Product
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Washington State University
SRP, Minocycline HCl Microspheres
Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg
The primary goal of this study is to investigate the qualitative and quantitative effects of scaling and root planing (SRP) with and without minocycline HCL microspheres, 1 mg on periodontal pathogens and overall bacterial load.
- Conditions
- SRP, Minocycline HCl Microspheres, Biomarkers
- Trial name
- NCT03762915
- Testing
- minocycline HCl microspheres
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Biomarkers
Changes in Biomarkers Associated With Use of Electronic Cigarettes
The objective of this clinical trial was to compare the effects of e-cigarettes with and without nicotine on patterns of combustible cigarette use and biomarkers of exposure to tobacco toxicants among African American smokers.
- Trial name
- NCT03084315
- Testing
- E-Cig Zero Nicotine, E-Cig 24mg Nicotine
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Minnesota
Triage, Risk Stratification With Biomarker
Risk Stratification in Acute Care: The Meaning of suPAR Measurement in Triage
Will clinical outcome for patients be improved if triage in Acute wards and Emergency rooms is supplemented with a prognostic biomarker?
- Trial name
- suPAR (NCT02643459)
- Testing
- suPAR measurement
- Where
- Denmark
- Volunteers
- 20,000 people
- Sponsor
- Herlev Hospital
Lung Cancer, Biomarkers
Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer
This study aims to evaluate the performance of serum free fatty acids as biomarkers for the identification of lung cancer.
- Conditions
- Lung Cancer, Biomarkers, Fatty Acids
- Trial name
- NCT01692951
- Testing
- serum sample
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- The Cleveland Clinic
FGFR Inhibition, Pharmacokinetics, Biomarkers, ER+ Breast Cancer
Safety and Efficacy of AZD4547 in Combination With Fulvestrant vs. Fulvestrant Alone in ER+ Breast Cancer Patients
The purpose of this study is to assess the safety and effectiveness of AZD4547 in combination with fulvestrant vs. fulvestrant alone in ER+ breast cancer patients with FGFR1 polysomy (FISH4/5) or gene amplification (FISH 6)
- Trial name
- GLOW (NCT01202591)
- Testing
- AZD4547, Exemestane, Fulvestrant
- Where
- 21 sites in Belgium, Czechia and 6 more
- Volunteers
- 127 people
- Sponsor
- AstraZeneca