Clinical trials: Bilateral Knee Osteoarthritis
Total Knee Anthroplasty, Osteoarthritis(Primary)
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Through a triple-blinded randomized control trial, the primary purpose of this pilot study is to assess the efficacy of administering peri-operative contralateral corticosteroid injection in patients undergoing TKA.
- Conditions
- Total Knee Anthroplasty, Osteoarthritis(Primary), Osteoarthritis (OA) of the Knee, Bilateral Knee Osteoarthritis
- Trial name
- COSTI (NCT06809998)
- Testing
- Corticosteroid Injection - 80mg methylprednisolone (total volume 2ml) with 6 mL of 1% Bupivacaine without epinephrine (Total Volume 8 mL)., Band-Aid
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Unity Health Toronto
Osteoarthritis, Knee, Postoperative Edema
Effect of Tergase Injection on Reducing Edema After Bilateral Total Knee Arthroplasty
This clinical trial is conducted to compare and evaluate the efficacy and safety of Tergase injection (4,500 IU) in reducing postoperative edema between treated and untreated knees in patients undergoing bilateral total knee…
- Conditions
- Osteoarthritis, Knee, Postoperative Edema, Bilateral Total Knee Arthroplasty
- Trial name
- ALT-TKA (NCT07705165)
- Testing
- Berahyaluronidase alfa
- Volunteers
- 30 people
- Sponsor
- Man Soo Kim
Bilateral Knee Osteoarthritis, Autologous Adipose Tissue
Bilateral Knee Osteoarthritis: Intra-articular Injection of Filtered Autologous Adipose Tissue Versus Placebo
The purpose of the study is to assess the radiological and clinical outcomes comparing two different treatments (Filtered Autologous Adipose Tissue versus Placebo) in patients affecting bilateral knee osteoarthritis.
- Trial name
- NCT04567732
- Testing
- injection of Filtered Autologous Adipose Tissue
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Bilateral Knee Osteoarthritis
Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Knee OA
This is a randomized, open-label, parallel group study to compare systemic exposure of triamcinolone acetonide following administration into both knees of either FX006 or TAcs.
- Trial name
- NCT03378076
- Testing
- FX006 32 mg, TAcs 40 mg
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Bilateral Knee Osteoarthritis
Comparison of Gait Pattern Between Simultaneous and Staged Knee Arthroplasties
Total knee arthroplasty is a well-known treatment of the end-stage osteoarthritis of the knee. In the case of bilateral end-stage knee osteoarthritis, both of the knees need total knee arthroplasty.
- Trial name
- NCT04975165
- Testing
- Total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Gulhane Training and Research Hospital
Gonarthrosis; Primary, Gonarthrosis
Comparison of Multiradius and Singleradius Total Knee Arthroplasty
The Investigators would like to compare multiradius and single-radius total knee arthroplasty using with association between sagittal patellar offset and anterior knee pain in subjects having undergone bilateral total knee…
- Conditions
- Gonarthrosis; Primary, Gonarthrosis, Gonarthrosis; Primary, Bilateral, Knee Osteoarthritis
- Trial name
- NCT04364971
- Testing
- singleradius and multiradius total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 494 people
- Sponsor
- Bezmialem Vakif University
Primary Gonarthrosis, Bilateral, Knee Osteoarthritis
Association Between Sagittal Patellar Offset and Anterior Knee Pain in Total Knee Arthroplasty
The aim of this study to evaluate whether the position of the sagittal patellar offset is a predictive factor for anterior knee pain in subjects having undergone bilateral multiradius total knee replacement.
- Conditions
- Primary Gonarthrosis, Bilateral, Knee Osteoarthritis, Knee Arthritis
- Trial name
- NCT04353440
- Volunteers
- 80 people
- Sponsor
- Bezmialem Vakif University
Bilateral Total Knee Arthroplasty, Gonarthrosis; Primary, Bilateral
Bilateral Simultaneous Total Knee Arthroplasty for Bilateral Gonarthrosis
The effects of two-team and single-team simultaneous bilateral total knee arthroplasty (SBA) on peri- and postoperative complications are not clear.
- Trial name
- NCT04299516
- Testing
- Two-team simultaneous bilateral total knee arthroplasty, Single-team simultaneous bilateral total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 246 people
- Sponsor
- Bezmialem Vakif University
Osteoarthritis, Bilateral Total Knee Arthroplasty
Outcomes Following Suction Drain and Non-suction Drain Assisted Total Knee Arthroplasty
This randomized controlled trial is designed to determine the effect of suction drain usage on the reduction of postoperative swelling following total knee replacement.
- Trial name
- NCT02693457
- Testing
- Drain, No Drain
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Colorado Joint Replacement
Bilateral Primary Osteoarthritis of Knee
Use of Autologous Bone Marrow Aspirate Concentrate in Painful Knee Osteoarthritis
The overall goal of this study is to develop regenerative cell therapy for use in patients with osteoarthritis (OA). The primary objective of this proposal is to conduct a pilot study that assesses the safety and feasibility of…
- Trial name
- BMAC (NCT01931007)
- Testing
- Autologous Bone Marrow Aspirate Concentrate, Sterile saline
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bilateral Knee Osteoarthritis
Gait, Stair Climbing and Postural Stability in Knee Osteoarthritis Patients After Hyaluronic Acid Injection
Treatment: five intro-articular Hyaluronic Acid injection Assessment has two parts, that are as follow: 1. Postural stability and risk of fall assessment using Biodex stability index and "Timed up and Go" test 2.
- Trial name
- NCT02063373
- Testing
- Hyaluronic acid
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Malaya