Clinical trials: Bilateral Cleft Palate
Cleft Lip and Palate
Evaluation of the Clinical Effectiveness of Naso-alveolar Molding (NAM) Versus Computer Aided Design NAM (CAD/NAM) in Infants With Bilateral Cleft Lip and Palate: A Randomized Clinical Trial
Bilateral cleft lip and palate neonates will be randomly assigned to one of two groups: (gp1 presurgical Naso-alveolar molding (NAM) using Grayson method, gp 2 computer aided design NAM (CAD/NAM).
- Trial name
- NCT02881606
- Testing
- Naso-alveolar molding (NAM), Computer aided design NAM (CAD/NAM)
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Cleft Lip and Cleft Palate
Evaluation of Nasal Elevator Versus Grayson's Nasal Stent with D-NAM Appliance on Nasolabial Esthetics in Bilateral Cleft Lip and Palate Infants
Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either nasal elevator or Grayson nasal stent in conjunction with digital nasoalveolar molding (D-NAM) appliance in order to evaluate their effect on the…
- Trial name
- D-NAM (NCT06589453)
- Testing
- Nasal elevator with digital nasoalveolar molding in bilateral cleft lip and palate infants, Nasal stent with digital nasoalveolar molding in bilateral cleft lip and palate infants
- Volunteers
- 20 people
- Sponsor
- Cairo University
Cleft Lip and/or Palate, Cleft Lip Bilateral
Conventional Versus Modified Pre-surgical Naso-Alveolar Molding Treatment in Cleft Lip and Palate Infants
The aim of this study is to evaluate and compare clinically conventional Pre-surgical Naso-Alveolar Molding (PNAM) treatment versus Modified Naso-Alveolar Molding protocol (MPNAM) in cleft lip and palate patients in terms of: 1.
- Trial name
- NCT06494098
- Testing
- Nasoalveolar Molding, Addition silicone impression
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bilateral Complete Cleft Lip and/or Alveolus
Tympanometric Analysis in Cleft Palate
Purpose: Characterize the profile of tympanometric patients with cleft lip and palate in the post surgery period and correlate it with the time of palatoplasty.
- Trial name
- NCT01820689
- Testing
- Tympanometry measurement
- Volunteers
- 16 people
- Sponsor
- Centro de Diagnostico Auditivo de Cuiaba
Complication Following Peripheral Nerve Block
Nalbuphine as Adjuvant During Bilateral Suprazygomatic Maxillary Nerve Block for Pediatric Cleft Palate Repair
The aim of this study is to evaluate the efficacy of adding nalbuphine to bupivacaine via suprazygomatic nerve block for postoperative pain control and emergence agitation management in pediatrics aged from to 1 to 7 years who…
- Trial name
- NCT06100315
- Testing
- Nalbuphine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Perioperative Inflammatory Response, Postoperative Pain
Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
the aim is to determine the value of adding bilateral supra zygomatic maxillary nerve block to general anesthesia in attenuating the systemic inflammatory response in paediatrics.
- Trial name
- NCT05495750
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alaa Mohamed Abdel Salam Ibrahim Soliman
Bilateral Cleft Lip and Palate, Maxillary Expansion
Efficiency of Two Maxillary Expanders for Maxillary Arch Expansion in Bilateral Cleft Lip and Palate Patients
This randomized controlled trial is designed to compare between Fan expander with palatal springs appliance vs three-way expander regarding the their effectiveness in maxillary expansion in patients with bilateral cleft
- Trial name
- NCT07056296
- Testing
- 3D Maxillary Expansion with 3 expansion screws, 3D Maxillary Expansion using modified Fan expander with springs
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cleft Palate Children, Block
Suprazygomatic Nerve Block vs Surgical Site Infiltration in Cleft Palate Repair
The aim of this study is to evaluate the efficacy and duration of effect of bupivacaine given preoperatively as a bilateral suprazygomatic maxillary nerve block and to compare it with peri-incisional infiltration with the same…
- Trial name
- NCT03799068
- Testing
- suprazygomatic maxillary nerve block, surgical site infiltration
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cleft Lip and Palate
Progression of Grafted Bone Density in Cleft Alveolus
The patients with unilateral and bilateral cleft lip and palate received alveolar bone graft surgery. Two time points of cone beam CT were taken for all the patients: post-operative 6 months, and post-operative 2 years.
- Trial name
- CDAABG (NCT04987190)
- Testing
- alveolar bone graft
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Cleft Lip and Palate, Bilateral Cleft Lip/Palate
Short Term Efficiency of Presurgical Vacuum Formed Nasoalveolar Molding Aligners in Infants With Bilateral Cleft Lip and Palate Compared With Grayson Acrylic Formed Nasoalveolar Molding Appliances.
Newborns with bilateral cleft lip/ palate will be treated pre-surgically by either presurgical vacuum-formed nasoalveolar molding aligners VF (NAM) or conventional Grayson acrylic formed nasoalveolar molding appliances in order…
- Trial name
- NCT04966572
- Testing
- Presurgical vacuum formed nasoalveolar molding aligners, Conventional Grayson acrylic formed nasoalveolar molding appliances
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip and Palate
Two Methods of Lip Taping as a Presurgical Orthopedic Appliance
A randomized clinical trial to compare the effectiveness of two methods of lip taping as a presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.
- Trial name
- NCT05796336
- Testing
- Lip taping
- Where
- Iraq
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Cleft Lip and Cleft Palate, Cleft Lip Bilateral
Improving the Outcomes of Nasoalveolar Molding in Complete Bilateral Cleft Lip and Palate Neonates Using a Modification in the Design of the Conventional Molding Appliance.
The goal of this clinical trial was to improve the outcome of using the nasoalveoalr molding appliances in patients with complete bilateral cleft lip and palate.
- Conditions
- Cleft Lip and Cleft Palate, Cleft Lip Bilateral, Complete Bilateral Cleft Lip and Palate
- Trial name
- NCT07814625
- Testing
- vomer molding appliance, conventional molding appliance
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Cleft Lip and Palate
Oral Hygiene and Connected Toothbrush Before Alveolar Bone Graft for Cleft Lip and Palate
Alveolar bone graft is an essential step in the primary surgical treatment of unilateral or bilateral cleft lip and palate. The procedure involves repairing the alveolar cleft by an autologous iliac bone graft.
- Trial name
- HBD-GPP (NCT03750708)
- Testing
- Ara® KOLIBREE tooth brush
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cleft Palate, Unilateral Cleft Palate
Palatoplasty Techniques Using PRF and Gentamicin-Loaded PRF in Cleft Palate
This prospective, randomized controlled trial evaluates the clinical efficacy of autologous Platelet-Rich Fibrin (PRF) and Gentamicin-Loaded PRF as regenerative and antimicrobial biological adjuncts in primary palatoplasty.
- Conditions
- Cleft Palate, Unilateral Cleft Palate, Bilateral Cleft Palate, Complete Cleft Palat
- Trial name
- NCT07752849
- Testing
- Standard palatoplasty ( control), Platelet _ Rich Fibrin ( PRF), gentamicin_ loaded PRF
- Where
- Yemen
- Volunteers
- 90 people
- Sponsor
- Al-Thawra Modern General Hospital
Cleft Palate, Cleft Lip
Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty
Early neonatal cheiloplasty is modified surgery protocol applied in the first week of newborn's life used for treating orofacial cleft patients.
- Conditions
- Cleft Palate, Cleft Lip, Cleft Lip and Palate, Cleft Lip, Bilateral
- Trial name
- NCT03839290
- Testing
- Early neonatal cheiloplasty
- Where
- Czechia
- Volunteers
- 137 people
- Sponsor
- Charles University, Czech Republic
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cleft Lip and Palate
The Effect of a Newly Designed Presurgical Orthopedic Appliance
A randomized clinical trial to compare the effectiveness of newly designed active type of presurgical orthopedic appliances on maxillary arch dimensions in infants with bilateral cleft lip and palate.
- Trial name
- NCT05535530
- Testing
- Active PSIO
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Baghdad