Clinical trials: Bilateral Cataract
Childhood Cataract
Increased Risk of ADHD Among Children With Bilateral Congenital Cataracts
In this study, the investigators conducted a cross-sectional, face-to-face investigation to evaluate the behavioral and psychological disorders and the risk of ADHD among children with bilateral congenital cataracts using the…
- Trial name
- NCT03692728
- Testing
- Psychological and Behavioral Problems
- Where
- China
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cataract, Multifocal Intraocular Lens
Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro
Title: Visual Outcomes in Patients Contralaterally Implanted with PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro Sponsor: Brian Shafer, MD, Shafer Vision Institute Objective: To compare visual…
- Trial name
- NCT07076277
- Testing
- Clareon PanOptix Pro and Clareon Vivity Intraocular Lens, Clareon PanOptix Pro Intraocular Lenses
- Where
- 5 sites in United States
- Volunteers
- 346 people
- Sponsor
- Brian Shafer
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
Dextenza Within Upper Lid Canaliculus Compared With Lower Lid Canaliculus Following Bilateral Cataract Extraction Surgery With PCIOL.
Assessing DEXTENZA efficacy when placed within the upper eyelid canaliculus as opposed to the lower eyelid canaliculus.
- Trial name
- NCT04592081
- Testing
- Dextenza 0.4Mg Ophthalmic Insert
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Kerry Assil, MD
Age-related Cataract
EDOF vs Enhanced vs Monofocal IOLs After Bilateral Cataract Surgery
Consecutive comparative case series evaluating visual outcomes and patientreported satisfaction after bilateral cataract surgery with implantation of the same IOL type (standard monofocal, enhanced monofocal, or novel EDOF IOL).
- Trial name
- NCT07548294
- Where
- Turkey (Türkiye)
- Volunteers
- 197 people
- Sponsor
- Sakarya Yenikent State Hospital
Cataract, Presbyopia
A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs
Since the introduction of intraocular lenses (IOL) in the treatment of cataract, the postoperative accommodative loss of the human eye has been a trending topic.
- Trial name
- NCT03117426
- Testing
- SYMFONY IOL, AT LISA tri 839MP IOL
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cataract Bilateral, Astigmatism Bilateral
Symfony Toric Intraocular Lens Visual Outcomes
In July 2016, the FDA approved an extended depth of focus (EDOF) IOL (Tecnis Symfony, Abbott Medical Optics) helping to improve the sharpness of vision at near, intermediate and far distances reducing the need of glasses after…
- Trial name
- NCT03082599
- Testing
- Presbyopia and astigmatism correcting intraocular lens
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract
Myopic Monovision: EDOF vs. Monofocal IOL
Comparison of EDOF IOLs versus monofocal IOLs with mini-monovision concerning intermediate and near visual acuity.
- Trial name
- NCT05194670
- Testing
- enhanced depth of focus IOL, monofocal IOL
- Where
- Austria
- Volunteers
- 62 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Bilateral Cataract
A Bioequivalence Study to Compare the Pharmacokinetics (PK) Of Marketed Product TobraDex® To An Experimental Ophthalmic Sterile Ointment Containing Tobramycin And Dexamethasone In Aqueous Humor In Patients Undergoing Indicated Cataract Surgery
Each patient will be randomized to receive one dose of the test article in one eye and one dose of the reference formulations in the contralateral eye.
- Trial name
- TBO (NCT02734459)
- Testing
- cataract surgery
- Volunteers
- 756 people
- Sponsor
- Semler Research Center Pvt. Ltd.
Presbyopia, Refractive Errors
Premium Monovision Versus Other Types of Monovision and Bilateral Trifocal Implantation.
Primary objective of this study was to compare the efficacy of premium monovision with Restor and Panoptix, against other prevalent monovision techniques and against bilateral Panoptix implantation in a sample of patients…
- Conditions
- Presbyopia, Refractive Errors, Cataract
- Trial name
- NCT04618380
- Testing
- bUD-VA,bUN-RA, bUI-RA, bUI-CPS, bUN-CPS, contrast sensitivity
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Democritus University of Thrace
Hyperalgesia, Cataract Bilateral Nos
Gabapentin Pretreatment for Staged Bilateral Cataract Operations
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
- Trial name
- NCT03826615
- Testing
- Gabapentin
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Cataract, Lenses
A Comparison of the Visual Performance of Trifocal Versus Extended Depth of Focus Intraocular Lenses
We are conducting a trial evaluating the performance of trifocal versus extended depth of focus intraocular lenses. These lenses will be implanted in otherwise healthy individuals with visual problems due to bilateral cataracts.
- Conditions
- Cataract, Lenses, Visual Impairment
- Trial name
- NCT03726606
- Testing
- Intraocular lens
- Volunteers
- 36 people
- Sponsor
- Hashmanis Hospital
Cataract
A Intra-patient Comparison of Closed Loop and Plate Haptic Toric Intraocular Lenses
During cataract surgery an artificial lens is implanted in the eye. These artificial lenses are called intraocular lenses (IOLs) and there are many different types of IOL designs.
- Trial name
- NCT02264457
- Testing
- T-flex Aspheric Toric IOL, AT TORBI toric IOL
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Plymouth
Cataract, Presbyopia
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population
The purpose of this study is to confirm the effectiveness of the investigational lens in a Korean population, especially for visual performance, quality of vision, and subject satisfaction with the visual outcome, as well as the…
- Trial name
- NCT03268746
- Testing
- AcrySof IQ PanOptix Multifocal IOL
- Where
- 4 sites in South Korea
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Cataract
A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects
This investigator-initiated trial is a prospective, randomized, parallel-group, bilateral implantation study comparing Clareon TruPlus versus Clareon monofocal intraocular lenses (IOLs).
- Trial name
- NCT07693205
- Testing
- Clareon TruPlus, Clareon monofocal
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Berkeley Eye Center
Age-related Cataract
EDOF and Multifocal IOL Study
The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- NCT05573529
- Testing
- phacoemulsification and intraocular lens implantation, intraocular lens implantation
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cataract
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study refined based on the Stage 1…
- Trial name
- NCT06922084
- Testing
- Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Cataract
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit.
- Trial name
- NCT06550375
- Testing
- TECNIS Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute
Cataract
A Prospective, Single-Arm Clinical Evaluation of Visual, Refractive, and Patient-Reported Outcomes Following Bilateral Implantation of the TECNIS PureSee™ Extended Depth of Focus Intraocular Lens
Assess the visual, refractive, and patient-reported outcomes - including spectacle independence - of bilateral cataract surgery with implantation of the TECNIS PureSee extended depth of focus (EDOF) IOL in subjects with visually…
- Trial name
- NCT07790887
- Testing
- PureSee IOL
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vance Thompson Vision
IOL, Cataract
Clinical Outcomes of Patients with LAL+ in At Least One Eye
The objective of this study is to collect data on bilateral pseudophakic patients implanted with the RxSight Light Adjustable Lens+ (LAL+) in at least one eye
- Trial name
- NCT06650358
- Testing
- Light Adjustable Lens+
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Frank A. Bucci, Jr., M.D.
Nuclear Sclerosis of the Lens, Phacoemulsification Cataract Surgery
This Clinical Trial Compares Two Phacoemulsification Systems Used in a Bilateral Cataract Surgery Subjects in Order to Study CDE and Ultrasound Time During Cataract Removal
This clinical trial compares two phacoemulsification systems used in a bilateral cataract surgery subjects, in order to study CDE and Ultrasound time during cataract removal
- Conditions
- Nuclear Sclerosis of the Lens, Phacoemulsification Cataract Surgery, Cataract Bilateral
- Trial name
- CDE (NCT07468877)
- Testing
- Cataract extraction with phacoemulsification comparing two systems
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nicole Fram M.D.