Clinical trials: Bilateral Breast Reduction
Pain
Enhanced Recovery After Bilateral Reduction Mammaplasty
This single-center, clinical trial is being conducted to determine whether non-narcotic pain regiments are as effective as narcotic-based regiments in reducing post-operative pain in patients undergoing breast reduction in the…
- Trial name
- NCT04558840
- Testing
- Macromastia
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Postoperative, Obesity
Bilateral Thoracic Paravertebral Blocks in Obese and Non-obese Patients Undergoing Reduction Mammaplasty
Aim: Although regional anesthesia (RA) techniques are advantageous in the anesthetic management of obese patients (body mass index (BMI)≥30); their performances can still be associated with technical difficulties and greater…
- Conditions
- Pain, Postoperative, Obesity, Thoracic Paravertebral Blocks, Ultrasound
- Trial name
- NCT04596787
- Testing
- Bilateral Thoracic paravertebral block
- Volunteers
- 82 people
- Sponsor
- Istanbul University
Macromastia
A Study to Evaluate Cutaneous Scar Quality Following Bilateral Breast Reduction With the PEAK PlasmaBlade 4.0
The objective of this clinical study is to evaluate scar quality following incision with the PEAK PlasmaBlade 4.0 using the Patient and Observer Scar Assessment Scale (POSAS), and to compare these results to equivalently-aged…
- Trial name
- PRECISE (NCT01284491)
- Testing
- PEAK PlasmaBlade 4.0, Traditional Electrosurgery with scalpel
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medtronic Surgical Technologies
Mammoplasty, Scarring
A Study of Granexin® Gel for the Reduction of Scar Formation in Surgical Wounds Following Bilateral Anchor Incision Breast Surgery
The purpose of this study is to evaluate effectiveness of Granexin® gel in reducing scar formation in surgical incisional wounds.
- Conditions
- Mammoplasty, Scarring, Scar, Breast Reconstruction
- Trial name
- NCT04331080
- Testing
- Granexin® gel 100 μM, Granexin® gel 200 μM, Vehicle gel
- Where
- 11 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Xequel Bio, Inc.
Pain, Postoperative
Ultrasound-Guided Thoracic Paravertebral Blocks in Patients Undergoing Reduction Mammoplasty
Background: Thoracic paravertebral blocks (TPVBs) have been effective for postoperative analgesia in mastectomy, thoracic and video-assisted thoracic surgeries.
- Trial name
- NCT02671851
- Testing
- Thoracic paravertebral blocks (TPVBs), IV metamizole sodium, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Pain, Postoperative
Opioid Counseling in Pain Management
The purpose of this study is to evaluate the effect of perioperative opioid counseling within a specific group of patient population who are undergoing bilateral reduction mammoplasty.
- Trial name
- NCT03985358
- Testing
- Opioid counseling plus standard of care instructions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Florida
Analgesia
Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
Bilateral reduction mammoplasty is one of the most commonly performed breast surgery. The Postoperative pain following it should be minimized.
- Trial name
- NCT06225895
- Testing
- general anesthesia, Erector spinae plane block, a rhomboid intercostal nerve block
- Where
- 2 sites in Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Breast Hypertrophy, Pain, Postoperative
Ultrasound Guided Bilateral Erector Spinae Plane Block Versus Tumescent Anesthesia
In breast reduction surgery, pain control is usually performed with tumescent anesthesia, thoracic epidural anesthesia, intercostal nerve blocks and paravertebral block applications.
- Trial name
- NCT03558880
- Testing
- Erector Spinae Plane Block, Tumescent Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Macromastia
PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade 4.0 during bilateral breast reduction; to monitor and record post-operative pain, adverse events and skin scarring following…
- Trial name
- PRECISE (NCT00986453)
- Testing
- PEAK PlasmaBlade, Traditional Electrosurgery with scalpel
- Where
- 7 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Pain, Postoperative
Single and Double Injection Bilateral Thoracic Paravertebral Blocks in Reduction Mammaplasty
This study compares the analgesic effects and dermatomal blockade distributions of single and double injection bilateral thoracic paravertebral block (TPVB) techniques in patients undergoing reduction mammaplasty.
- Trial name
- NCT04517331
- Testing
- Thoracic paravertebral block-single injection, Thoracic paravertebral block-double injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Post Operative Pain, Opioid-Related Disorders
Erector Spinae Plane Block Versus Serratus Anterior Plane Block
the aim of the study compare the analgesic effect of erector spinae block and serratus anterior block in breast surgery
- Trial name
- NCT06862752
- Testing
- erector spine plane (ESP) block, Serratus Anterior Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hematoma Postoperative, Tranexamic Acid
Topical Tranexamic Acid for Bilateral Breast Reduction Surgery
Hematoma is a common complication of bilateral breast reduction (BBR) surgery. This can lead to pain and discomfort experienced by the patient, in addition to greater use of valuable healthcare resources.
- Trial name
- NCT04918576
- Testing
- Tranexamic acid, Normal Saline
- Where
- 3 sites in Canada
- Volunteers
- 106 people
- Sponsor
- McMaster University
Mammaplasty, Cicatrix
Juvista (Avotermin) in Breast Reduction Surgery Scars
Severe scarring is a common problem following breast reduction surgery, studies have shown that over 64% of patients develop a hypertrophic scar at three months after the operation.
- Trial name
- NCT00432328
- Testing
- Avotermin
- Where
- 6 sites in United Kingdom
- Volunteers
- 39 people
- Sponsor
- Renovo
Abdominoplasty, Bilateral Breast Reduction
Megadyne Ace Incision/Dissection Study
The Megadyne Ace™ Incision/ Dissection study is a post market, prospective assessment of the E-Z Clean ACE electrosurgical electrodes using the ACE Blade in the ACE Mode for targeted procedures such as abdominoplasty, bilateral…
- Conditions
- Abdominoplasty, Bilateral Breast Reduction, Bilateral Breast Lift, Bilateral Brachioplasty
- Trial name
- ACE (NCT01175889)
- Testing
- E-Z Clean ACE Blade
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Megadyne Medical Products Inc.
Pain Management
Serratus Plane Block For Breast Reduction Surgery
Serratus plane block was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves. And this block provides sufficient analgesia lateral anterior and posterior part of thoracic…
- Trial name
- SPB (NCT02930733)
- Testing
- Bupivacaine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ataturk University
Breast Carcinoma
Cosmetic Evaluation of Lumpectomy Versus Oncolytic Mammoplasty With Bilateral Breast Reduction for Early Stage Breast Cancer
This study will evaluate the cosmetic outcome and examine factors contributing to cosmetic outcome in women treated with lumpectomy or bilateral breast reduction mammoplasty/mastopexy (BRM) followed by hypofractionated whole…
- Trial name
- NCT01400399
- Where
- 3 sites in United States
- Volunteers
- 84 people
- Sponsor
- Coastal Carolina Radiation Oncology
Postoperative Pain, Breast Hypertrophy
Bilateral Ultrasound-Guided Erector Spinae Plane Block For Postoperative Analgesia in Breast Reduction Surgery
Erector spinae plane (ESP) block is a novel block developed by Forero to treat severe neuropathic pain and was firstly reported in 2016.
- Trial name
- NCT03621345
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Macromastia (Symptomatic)
Use of the PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade® 4.0 during bilateral breast reduction; to monitor and record post-operative pain, adverse events and skin scarring following…
- Trial name
- NCT01404351
- Testing
- PEAK PlasmaBlade, Scalpel and Traditional Electrosurgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Capsular Contracture Associated With Implant, Foreign-Body Reaction
Experimental and Clinical Investigation of the Implant Surface Roughness Reduction Effect on Early-stage Fibrosis
The goal of this single-center, randomised double-blinded trial is to compare the early stage fibrosis progression around conventional textured expander and the SmoothSilk® expander with reduced surface roughness in women…
- Conditions
- Capsular Contracture Associated With Implant, Foreign-Body Reaction, Wounds and Injuries, Tissue Expander Disorder
- Trial name
- NCT05648929
- Testing
- Patient Satisfaction Questionnaire, Pregnancy test, Blood draw
- Where
- Austria
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck