Clinical trials: Benzodiazepines Deprescribing
Geriatric Patients
Attitudes and Beliefs Related to Benzodiazepine Deprescribing
The use of benzodiazepines in older adults is associated with an increased risk of adverse effects due to age-related physiological changes.
- Trial name
- BENZ-AC (NCT07474532)
- Testing
- Patient rPATD Benzo questionnaire, Geriatrician rPATD Benzo questionnaire
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Benzodiazepines Deprescribing
Benzodiazepines Deprescribing in Nursing Homes: Intervention Feasibility
The goal of this feasibility study is to evaluate the feasibility of a complex intervention towards benzodiazepines and Z-drugs deprescribing in older adults living in the Belgian nursing home setting.
- Trial name
- END-IT NH (NCT05929443)
- Testing
- END-IT intervention for nursing homes
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Université Catholique de Louvain
Deprescription, Benzodiazepine (BZD) and Related Drugs
Multimodal Educative Data Feedback for Deprescribing BZD and Related Drugs in Outpatients: a Cluster RCT
Benzodiazepine (BZD) and related drugs are sedative anxiolytics and hypnotics that should be avoided especially in people aged 65 years and older, given the high risk of falling, fracture, dependence, respiratory depression and…
- Trial name
- NCT05859555
- Testing
- Thematic quality circles - Deprescription
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Réseau de soins Delta
suspensión Completa Del Tratamiento Con Benzodicepinas, Disminución Del Consumo Benzodiacepinas
Evaluation of the Effectiveness of a Psychoeducational Intervention on Benzodiazepine Use in the Population Over 64 Years Old in Primary Care
The goal of this pragmatic, multicenter, randomized controlled trial is to determine whether a multidisciplinary psychoeducational intervention combined with therapeutic exercise is more effective than a minimal educational…
- Trial name
- BENZOS-AP (NCT06950567)
- Testing
- psycho-educational intervention and therapeutic activity, Control
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Frailty, Deprescription
Understanding Benzodiazepine and Non-benzodiazepine Sedative Use
Inappropriate medication use among the elderly ranges from 11% to 62% and is a major concern for patient safety. Benzodiazepines account for approximately 20 to 25% of inappropriate medications prescribed to the elderly, thus…
- Conditions
- Frailty, Deprescription, Aged
- Trial name
- NCT02833272
- Testing
- EMPOWER Educational Brochure
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Benzodiazepine-Related Disorders
Informative Exhibition for Deprescribing Benzodiazepines
The goal of this trial is to determine if an interactive and informative exhibition in the waiting room of a Primary Care Clinic can reduce the use of benzodiazepines in adults.
- Trial name
- ESUB (NCT06467019)
- Testing
- Informative Session
- Where
- Spain
- Volunteers
- 6,410 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Anxiety, Insomnia
Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults
The main purpose of this 12-week study is to see if a new combination of treatments can help older adults reduce benzodiazepine or related medication use.
- Conditions
- Anxiety, Insomnia, Benzodiazepine, Deprescription
- Trial name
- NCT06197243
- Testing
- Acupuncture, Yoga, Deprescribing
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Benzodiazepine Deprescribing
Benzodiazepines Deprescribing in the Community Setting: Intervention Feasibility
The goal of this feasibility study is to evaluate the feasibility of an intervention, led by the pharmacist, aiming at benzodiazepines and z-drugs deprescribing in older adults living in the Belgian community setting.
- Trial name
- END-IT CS (NCT05929417)
- Testing
- END-IT intervention for the community setting
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Université Catholique de Louvain
Insomnia Chronic
Protocol - Your Answers When Needing Sleep in New Brunswick
New Brunswick has an aging population with Canada's highest rate of sleeping pill use. The rate of long-term (chronic) use among NB seniors is 25%, well in excess of the Canadian average of 10%.
- Trial name
- YAWNS NB (NCT04406103)
- Testing
- Sleepwell, Empower
- Where
- Canada
- Volunteers
- 594 people
- Sponsor
- David Gardner
Prevention, Benzodiazepine Dependence
Electronic Deprescribing Tool for the Prevention of PIP
This study is a cluster randomized control trial aimed to measure the effectiveness of an educational knowledge transfer intervention to prescribers on the discontinuation of two targeted classes: Benzodiazepines…
- Trial name
- NCT03192514
- Testing
- Electronic Deprescribing tool
- Where
- Portugal
- Volunteers
- 280 people
- Sponsor
- University of Beira Interior
Primary Care, Health Plan Implementation
Effectiveness of a Joint General Practitioner-Pharmacist Intervention on Benzodiazepine Deprescribing in the Elderly
Benzodiazepines or related drug (BZDR) are consumed for hypnotic or anxiolytic purposes in most cases. The consequences of BZDR are multiple with an increased risk of daytime sedation, balance disorders leading to falls and…
- Conditions
- Primary Care, Health Plan Implementation, Benzodiazepine Dependence, Elderly
- Trial name
- BESTOPH-MG (NCT05765656)
- Testing
- GP - pharmacist collaboration and pharmacist motivational interviewing
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Nantes University Hospital
Benzodiazepines Deprescribing, Sleep Problems
Improving Patient Safety by Supporting Older Adults in Managing Sleep Problems.
Among older adults (≥65 years), use of sleeping pills, such as benzodiazepines and other sedative-hypnotics, to treat sleep problems is common.
- Trial name
- BE-SAFE (NCT06584513)
- Testing
- Specific tapering plan for sleep medication, educational and cognitive behavioural therapy elements
- Where
- 6 sites in Belgium, Greece and 4 more
- Volunteers
- 470 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anxiety, Insomnia
Remote Yoga Nidra for Deprescribing BZRAs
The overall goal of this application is to assess feasibility and impact of a remotely delivered guided meditation practice called Yoga Nidra, for reducing or stopping use of Benzodiazepine Receptor Agonists (BZRAs) for insomnia…
- Trial name
- NCT06353919
- Testing
- Yoga Nidra, Sleep Hygiene, Anxiety, and Benzodiazepine Receptor Agonist Education
- Volunteers
- 40 people
- Sponsor
- National University of Natural Medicine
Hypnotic Withdrawal
The Impact of a Pharmacist Intervention on Post-discharge Hypnotic Drug Discontinuation in Geriatric Inpatients
This study investigated whether a multifaceted approach was associated with hypnotic drug discontinuation at one month after discharge
- Trial name
- NCT05521971
- Testing
- multifaceted pharmacist-led intervention, Usual care group
- Volunteers
- 173 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Benzodiazepine Dependence, Anxiety Disorders
Anxiety Lowering and Deprescribing Through Emotion Regulation
The goal of this clinical trial is to test ALDER (Anxiety Lowering and Deprescribing through Emotion Regulation), an online self-guided positive emotion intervention, in patients over the age of 65 who are candidates for…
- Conditions
- Benzodiazepine Dependence, Anxiety Disorders, Sleep Disturbance
- Trial name
- ALDER (NCT06359314)
- Testing
- ALDER
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Benzodiazepine Use, Insomnia
Brief Cognitive Behavioral Therapy to Enhance Benzodiazepine Deprescribing
The goal of this clinical trial is to conduct a single-arm pilot trial of a brief cognitive-behavioral therapy-enhanced benzodiazepine deprescribing intervention in 20 older adults (aged ≥55 years) prescribed chronic…
- Conditions
- Benzodiazepine Use, Insomnia, Anxiety
- Trial name
- NCT06119308
- Testing
- Benzodiazepine Medication Taper with Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Beth Israel Deaconess Medical Center