Clinical trials: Benchmark, open to volunteers
Severe Traumatic Brain Injury
Benchmark Evidence Led by Latin America: Trial of Intracranial Pressure - Pediatrics
Narrative: Worldwide, traumatic brain injury (TBI) is a leading cause of death and disability among children and adolescents. The Investigators aim to test whether pediatric TBI treatment guided by invasive intracranial pressure…
- Trial name
- BELA TRIPP (NCT05566431)
- Testing
- ICP, CREVICE
- Where
- 11 sites in United States, Colombia and 4 more
- Volunteers
- 428 people
- Sponsor
- University of Washington
Athletes, Soccer
Relationship of Anthropometric Profile and Fitness Indicators With Sports Performance of Elite Mexican National Team Soccer Players
Relating Anthropometric Profile to Fitness and Sports Performance in Mexican National Team Soccer Players
- Trial name
- ANTHROPERFORMX (NCT06941064)
- Testing
- Anthropometric and sports performance assessment
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- Iberoamerican Institute of Sports Science and Human Movement
Breast Carcinoma
Comparison of Synthetic Mammography Versus Full-Field Digital Mammography in Image Interpretation and Performance Metrics
This study compares synthetic mammography to full-field digital mammography in image interpretation and performance metrics. Digital breast tomosynthesis (DBT) has previously been found to be superior in performance to standard…
- Trial name
- NCT05056818
- Testing
- Electronic Health Record Review
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoarthritis of the Hip or Knee
Implementing a Guideline-based Model of Care for Hip and Knee Osteoarthritis in Finland. A Benchmarking-controlled Trial (FIN-OA)
This project aims to bridge the gap between guideline recommendations and clinical practice in osteoarthritis (OA) management. By implementing a systematic, evidence-based model of care, the project seeks to improve patient…
- Trial name
- FIN-OA (NCT06904885)
- Testing
- Implementation of a guideline-based model of care for hip and knee osteoarthritis
- Volunteers
- 10,000 people
- Sponsor
- University of Jyvaskyla
Coronary Artery Disease (CAD)
Predicting Plaque Growth Using Blood Flow Stress Markers: A Proof-of-Concept Study
Coronary artery disease occurs when fatty deposits (plaques) build up inside the arteries that supply blood to the heart. Some plaques remain stable, while others continue to grow or become more likely to rupture, which can lead…
- Trial name
- POSSEM (NCT07864051)
- Testing
- PCCTA scan, Endothelial cell isolation from peripheral blood sample
- Where
- United Kingdom
- Volunteers
- 270 people
- Sponsor
- Queen Mary University of London
Breast Neoplasms, Breast Diseases
Construction of a Benchmark for Breast Ultrasound AI Interpretation and Performance Evaluation of Multimodal AI Models
This single-center, retrospective, observational study aims to construct a standardized benchmark evaluation system for intelligent breast ultrasound image interpretation and to systematically assess the diagnostic performance of…
- Conditions
- Breast Neoplasms, Breast Diseases, Ultrasonography
- Trial name
- BUST-AI Bench (NCT07500428)
- Testing
- Multimodal AI Model Diagnostic Evaluation
- Where
- China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
No Disease or Condition is Being Studied, Surgical Procedures, Minimally Invasive
Hand Versus Foot Controls for Robotic Surgery Simulation
Why is the study being done? Robotic-assisted surgery offers high precision and ergonomic benefits, but it requires specialized console skills that differ significantly from traditional open or laparoscopic surgery.
- Trial name
- CLUTCH WAR (NCT07618429)
- Testing
- Hand Clutch, Foot Clutch
- Where
- Thailand
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Autism Spectrum Disorders
Single Dose Double-blind, Placebo-controlled Cross-over (SDDBPCCO) Shiftability Study, Will be Followed by a 10-week Open-label Study With Arbaclofen (4 Weeks of Titration and Then 6 Weeks of Active/Stable Treatment). The Effects of Arbaclofen on Target EEG and ERG Metrics Will be Associated With th
study with arbaclofen (4 weeks of titration and then 6 weeks of active/stable treatment). The effects of arbaclofen on target EEG and ERG metrics will be associated with the clinical response in measures of social and general…
- Trial name
- NCT07655115
- Testing
- Arbaclofen
- Where
- 5 sites in France, Spain
- Volunteers
- 103 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Acceptability Study, Real-use Conditions
Evaluation of Clinical, Perceived and Instrumental Efficacy of a Scar Gel in Preventing Hypertrophic Scars
Evaluation of the safety and topical efficacy of a scar gel after 90 days of continuous use, comparing it to a benchmark for preventing hypertrophic scars and improving appearance, hydration and pigmentation.
- Conditions
- Acceptability Study, Real-use Conditions, Safety and Efficacy, Topical Administration
- Trial name
- NCT06751433
- Testing
- Scar gel, Scar gel comparator
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Kidney Disease, Kidney Injury
Transgender Analysis of Nephrological Studies Focused on Renal Metrics
This study investigates how sex hormones affect kidney function in people undergoing gender-affirming hormone therapy (GAHT). We know men have a faster progression of kidney disease.
- Conditions
- Kidney Disease, Kidney Injury, Transgender Individuals
- Trial name
- TRANSFORM (NCT07542964)
- Testing
- P-aminohippurate clearance study, Iohexol infusion, Hyperinsulinemic clamp
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Amsterdam UMC, location VUmc
Breast Cancer
Reiki Breast Surgery QOL Project for Women Undergoing Breast Surgery
This pilot study will examine the impact of pre-operative Medical Reiki© on the psychosocial well-being and recovery of underserved women undergoing breast cancer surgery.
- Trial name
- NCT06524895
- Testing
- Medical Reiki
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Albert Einstein College of Medicine
Diabetes Mellitus, Type 1
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
The goal of this clinical trial is to determine if transitioning to automated insulin delivery (AID) systems, can improve objectively measured sleep quality and quantity and alleviate cardiovascular risk factors in both children…
- Trial name
- AID-BEYOND (NCT06469593)
- Testing
- Automated insuling delivery system
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Steno Diabetes Center Copenhagen
Type 1 Diabetes Mellitus
Effect of Inulin Supplementation on Glycaemic Control and Immunological Parameters in Type 1 Diabetes (2024)
The goal is to establish the effect of oral inulin supplementation on continuous glucose monitoring (CGM) metrics and immunological parameters in adults with type 1 diabetes.
- Trial name
- INCREASE (NCT07050888)
- Testing
- Inulin (prebiotic, fermentable fiber)
- Where
- 2 sites in Netherlands
- Volunteers
- 76 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Body Compostition
Sea Buckthorn Aqueous Infusion Impact
A total of 60 overweight women (BMI 25-29.9 kg/m²), aged 18-50years, will be enrolled and randomized equally into intervention and control groups.
- Trial name
- Sbaii (NCT07313423)
- Testing
- Sea buckthorn aqueous infusion
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Veterinary and Animal Sciences, Lahore - Pakistan
Cerebral Palsy (CP)
Wearable Eye Tracking During Bimanual Tasks in Children With Cerebral Palsy
This observational pilot study will include 40 children and adolescents aged 6 to 12 years: 20 with cerebral palsy and 20 with typical development.
- Trial name
- NCT07806994
- Testing
- Wearable Eye-Tracking Assessment During Structured Bimanual Tasks
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Patient Safety, Medical Errors
Specialist Review of Harm Ratings for Clinical Responses Acronym: NOHARM
The purpose of this study is to determine how closely potential-harm ratings assigned using the NOHARM rubric agree with independent ratings from specialty-matched physicians.
- Trial name
- NCT07823062
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Stanford University
COPD (Chronic Obstructive Pulmonary Disease), Airway Disease
Comparing Advanced Technologies to Standard Testing for the Diagnosis of Airway Disease in Hospital and Community Settings
Airway disease, such as chronic obstructive pulmonary disease (COPD), is usually diagnosed through breathing tests like spirometry.
- Trial name
- BREATHE (NCT07798596)
- Testing
- Capnography, Oscillometry, FENO
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Chronic Pain
EVA: Evaluation of EVOKE Therapy Metrics Generated Using the Evoke System With EVA
The Evoke Spinal Cord Stimulator (SCS) System (Evoke® System) is an FDA-approved device that is used to manage long lasting, severe pain that is not relieved by typical medical treatments.
- Trial name
- NCT07267715
- Testing
- Spinal Cord Stimulation (SCS) System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dustin Reynolds, MD
Melanoma
Studying Quality of Life Inclusive of Mental Health and Cognitive Behavioral Therapy for Cancer Distress for the Improvement of Quality of Life in Stage III-IV Melanoma Patients
This clinical trial studies how people feel and live during the first two years after being treated for melanoma and whether cognitive behavioral therapy for cancer distress (CBT-C) works to improve quality of life in patients…
- Trial name
- NCT07379138
- Testing
- Best Practice, Cognitive Behavior Therapy, Electronic Health Record Review
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mayo Clinic