Clinical trials: Behavioral Disorder
Opiate Substitution Treatment
Buprenorphine and Substance Abuse Services for Prescription Opioid Dependence
This is a randomized trial of two group-based models of care for buprenorphine/naloxone (bup/nx) patients in Substance Use (SU) specialty treatment: Standard Medical Management (SMM) and Intensive Outpatient Treatment (IOT).
- Trial name
- NCT02496403
- Testing
- Standard Medical Management (SMM)
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- Kaiser Permanente
Hypothyroidism
Interventional Study to Improve Medication Adherence Using Patient Decision Aid
Background: Although hypothyroidism is easily treated with levothyroxine (LT4) replacement, results from several studies indicate that people receiving LT4 replacement often have under- or over-replaced thyroid function.
- Trial name
- IMPART (NCT06205303)
- Testing
- Patient Decision Aid (Video)
- Where
- Singapore
- Volunteers
- 236 people
- Sponsor
- SingHealth Polyclinics
Anxiety, Depression
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Depression and anxiety disorders rank in the top ten causes of years lived with disability. Less than 50% of patients experiencing long-lasting improvements to current gold-standard treatments.
- Trial name
- AAC-BeT (NCT04426461)
- Testing
- Behavioral Activation, Exposure-based therapy, Supportive therapy
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Laureate Institute for Brain Research, Inc.
Diabetes, Metabolic Diseases
The Fasting II Study
This study will determine whether an intensive fasting protocol alters hemoglobin A1c measurements or other markers of metabolic and cardiovascular risk by performing a 5-week clinical trial of fasting among 12 pre-diabetic…
- Trial name
- NCT01792986
- Testing
- water-only 24-hour fasting once per week for 6 weeks
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Intermountain Health Care, Inc.
Autism
Use of Functional Behavioral Assessments to Evaluate Stereotypy and Repetitive Behaviors in a Double-blind, Placebo Controlled Trials of Various Medications Used to Treat Children With Autism.
Autism, originally described by Kanner (1943), is among the most severe of neuropsychiatric disorders. It is a pervasive developmental disorder affecting social, communicative, and compulsive/repetitive behaviors characterized by…
- Trial name
- NCT00211770
- Testing
- Behavioral Assessment
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pediatric Obesity, Time Restricted Feeding
Early vs. Late Time-Restricted Eating in Adolescents With Obesity (EL TREA)
Determine the effectiveness of how limiting the time you eat within an early or late eating window and fasting for remainder of the day will impact weight loss and body mass index (BMI).
- Conditions
- Pediatric Obesity, Time Restricted Feeding, Time Restricted Eating
- Trial name
- NCT05740254
- Testing
- Early Time Restricted Eating, Late Time Restricted Eating
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Children's Hospital Los Angeles
Stress Disorders, Post-Traumatic, Helping Behavior
Clinical Trial of a Supporter-Targeted Intervention to Improve Outcomes in Recent Sexual Assault Survivors
Communication and Recovery Enhancement (CARE) is a 2-session early intervention for survivors of recent sexual assault and their supporters that aims to improve supporters' ability to respond effectively.
- Conditions
- Stress Disorders, Post-Traumatic, Helping Behavior, Help-Seeking Behavior, Stress
- Trial name
- CARE (NCT05345405)
- Testing
- Dyadic CARE, Supporter-Only CARE
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Washington
Depressive Disorder, Major
Efficacy and Safety Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
The purpose of this study is to evaluate the efficacy of vortioxetine, once daily (QD), compared with placebo in adults with major depressive disorder.
- Trial name
- NCT01163266
- Testing
- Vortioxetine
- Where
- 39 sites in United States
- Volunteers
- 462 people
- Sponsor
- Takeda
Human Papillomavirus Infection, HPV Vaccines
The Role of Cyberchondria Severity in the Relationship Between HPV Awareness and Vaccination Attitudes in Adult Women
Human papillomavirus (HPV) is a prevalent sexually transmitted infection linked to nearly all cases (99%) of cervical cancer. Prophylactic HPV vaccination is effective in preventing these cancers, complemented by HPV screening…
- Conditions
- Human Papillomavirus Infection, HPV Vaccines, Cyberchondria, Awareness
- Trial name
- NCT06800456
- Where
- Turkey (Türkiye)
- Volunteers
- 337 people
- Sponsor
- Acibadem University
Fertility
Bladder Exstrophy (FIVES FertIlity Vesical Exstrophy Sexuality)
This analytical descriptive study aims to describe the fertility and sexuality male adult subjects carrying classic bladder exstrophy or epispadias and to highlight infertility risk factors.
- Trial name
- FIVES (NCT02759705)
- Sponsor
- Hospices Civils de Lyon
Alcoholism, Alcohol Dependence
Behavioral Therapy Plus Naltrexone for Alcoholism
This study will compare cognitive behavioral therapy with a time-limited motivational enhancement therapy to which naltrexone (Revia) or placebo medication is added.
- Trial name
- NCT00000456
- Testing
- naltrexone (Revia), cognitive behavior therapy, motivational enhancement therapy
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Medical University of South Carolina
Cancer, Breast, Cancer Colorectal
Impact of a Patient Decision Aid Intervention
Studies evaluating decisions aids have used a wide range of outcome measures as well as formats and settings. Most studies have focused on patient decision aids used either within the consultation or delivered pre-consultation…
- Trial name
- IMPACTT (NCT05573022)
- Testing
- Pre-consultation electronic patient decision aid, In-consultation paper-based patient decision aid
- Where
- Denmark
- Volunteers
- 274 people
- Sponsor
- Vejle Hospital
Depressive Symptoms
Ecological Momentary Intervention for Depressive Symptoms in a Community Sample in Hong Kong
The key aim of the study is to test the efficacy of a 4-week ecological momentary intervention (EMI), as compared with the regular weekly-based intervention (control group), in reducing (1) symptoms of depression and (2)…
- Trial name
- NCT04985422
- Testing
- Smartphone-based Daily Ecological Momentary Intervention, Smartphone-based Weekly-delivered Information
- Where
- Hong Kong
- Volunteers
- 262 people
- Sponsor
- The University of Hong Kong
Tobacco Use
Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs
The goal of this research is to assess whether little Cigars and cigarillos (LCC) warnings developed by the study team are more effective than the current warnings proposed by FDA for LCC products.
- Trial name
- NCT05849051
- Testing
- Newly developed warnings with images at 30% size, FDA proposed text-only warnings at 30% size
- Where
- United States
- Volunteers
- 1,029 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD)
Artificial Intelligence-based Parkinson's Disease Risk Assessment (AI-PRA) Study
The study aims to provide initial proof-of-concept validation data of an artificial intelligence-based model to estimate individual Parkinson's disease risk using demographic, clinical, genetic information and digital biomarker…
- Conditions
- Parkinson Disease (PD), REM Sleep Behavior Disorder (iRBD), Neurogenic Orthostatic Hypotension, Hyposmia
- Trial name
- AI-PRA (NCT07706829)
- Testing
- Smartwatch and phone app
- Where
- 3 sites in France, Spain and 1 more
- Volunteers
- 60 people
- Sponsor
- Queen Mary University of London
Aneurysms, Arteriovenous Malformations
Neurosurgical Outcome Network
The evaluation of neurosurgical outcomes varies from center to center, and the predictive factors that determine these outcomes are not fully known or shared.
- Conditions
- Aneurysms, Arteriovenous Malformations, Cavernomas, Skull Base Tumors
- Trial name
- NEON (NCT06724029)
- Where
- 27 sites in Italy
- Volunteers
- 4,500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Parkinson Disease
Pilates as an Adjuvant Therapy in Parkinson Disease.
Although Pilates has been proposed as a useful rehabilitation strategy in PD, research on its feasibility and potential effects on the motor symptoms and balance with this population is scarce.
- Trial name
- NCT03294031
- Testing
- Pilates, Conventional Exercise
- Volunteers
- 15 people
- Sponsor
- University of Vigo
Diabetes Mellitus, Type 1
Cognitive-Behavioral Therapy (CBT) in Children With Diabetes
Diabetes mellitus in children and adolescents is a source of stress and poor quality of life for themselves and their family. Development of adaptive coping strategies may be improved by focused parent and children training.
- Trial name
- DI-CO (NCT02839031)
- Testing
- "CBT" (Cognitive-Behavioral Therapy), Control (telephonic support without CBT content)
- Where
- France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Montpellier
Exercise, Low Back Pain
McGill Exercise With and Without 3-dimensional Myofascial Release Technique in Non-specific Low Back Pain
Low back pain is a complex of musculoskeletal disorders or muscular imbalance and one of the most common problems of patients referred to physiotherapy clinics, but still diagnosis and especially the provision of special back…
- Conditions
- Exercise, Low Back Pain, Lumbar, Lordosis
- Trial name
- NCT07441031
- Testing
- McGill exercise with 3 D Myofascial Release., McGill exercise without 3-D MFR
- Where
- Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Rumination
Comparison of Diaphragmatic Breathing and Muscle Relaxation for Rumination
Rumination is an upper gastrointestinal (GI) disorder characterized by the frequent regurgitation of recently ingested food. Very little is understood about the nature and treatment of this disorder.
- Trial name
- NCT01576302
- Testing
- Diaphragmatic breathing, Muscle relaxation
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic