Clinical trials: Barotrauma
Decompression Sickness, Barotrauma
Health, Fitness, and Safety Knowledge as Determinants of Adverse Events in Recreational Divers in Poland
This cross-sectional online survey study assesses health status, physical fitness, and safety knowledge as potential determinants of diving-related adverse events among recreational divers in Poland.
- Conditions
- Decompression Sickness, Barotrauma, Recreational Diving
- Trial name
- DIVE-PL (NCT07855861)
- Testing
- Anonymous online questionnaire
- Where
- 2 sites in Poland
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Hyperbaric Oxygen Therapy, Middle Ear Barotrauma
Effect of Self-acupressure on Middle Ear Barotrauma Associated With Hyperbaric Oxygen Therapy
Middle ear barotrauma (MEB) is the most common complication during hyperbaric oxygen therapy (HBOT). Though Valsalva and Toynbee maneuvers have been proposed to prevent MEB, still some patients discontinue HBOT due to severe…
- Trial name
- NCT04311437
- Testing
- Self-acupressure therapy, Combined Valsalva and Toynbee maneuvers
- Where
- Taiwan
- Volunteers
- 152 people
- Sponsor
- Chang Gung Memorial Hospital
Otic Barotrauma, Pressure Injury
Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System
This validation study investigates the diagnostic precision and accuracy when grading otic barotrauma using two alternative gradings systems including the TEED and the OGS grading systems.
- Conditions
- Otic Barotrauma, Pressure Injury, Ear Injury, Barotitis
- Trial name
- OGS (NCT04726306)
- Testing
- Otic Barotrauma Grading System
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Ear Barotrauma, Middle Ear Disease
Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury
- Trial name
- NCT04804098
- Testing
- Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
- Where
- United States
- Volunteers
- 1,553 people
- Sponsor
- Northwell Health
Barotrauma;Ear, Tympanum; Perforation
Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions
Middle ear barotrauma represents the predominant complication associated with hyperbaric oxygen therapy, manifesting symptoms ranging from otalgia to tympanic membrane perforation.
- Trial name
- NCT06408363
- Testing
- Maneuver group
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Felicio Rocho
Barotrauma
Barotrauma in Hyperbaric Oxygen Therapy
The purpose of this research is to study whether the use of pseudoephedrine can help prevent middle ear trauma during HBOT. Pseudoephedrine is an approved drug that is used for temporary relief of nasal or sinus pain and pressure.
- Trial name
- HBOT (NCT05697328)
- Testing
- Pseudoephedrine Pill
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- John Muir Health
Acute Respiratory Distress Syndrome, Barotrauma
Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS)
Barotrauma (pneumothorax, pneumomediastinum) is a well-described complication of Acute Respiratory Distress Syndrome (ARDS), especially in patients with coronavirus disease 2019 (COVID-19) (16.1% in COVID-19, and about 6% in…
- Trial name
- PIE-ARDS (NCT06001645)
- Testing
- Blood and bronchoalveolar fluid collection and analysis, Chest CT scan
- Where
- 4 sites in Italy
- Volunteers
- 110 people
- Sponsor
- Università Vita-Salute San Raffaele
Acute Respiratory Distress Syndrome, Barotrauma
Imaging Biomarkers to Stratify the Risk of Barotrauma in ARDS
The high incidence of barotrauma in patients with COVID-19-related acute respiratory distress syndrome (ARDS) (16.1%, with a mortality rate >60%) provides rationale for considering COVID-19 ARDS a paradigm for lung frailty.
- Trial name
- FRAIL ARDS (NCT05816954)
- Testing
- Chest Computed Tomography Scan per normal clinical practice
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Università Vita-Salute San Raffaele
Barotrauma;Ear
Pseudoephedrine Prophylaxis for Prevention of Middle Ear Barotrauma in Hyperbaric Oxygen Therapy
Hyperbaric oxygen therapy (HBOT) utilizes 100% oxygen delivery at a pressure greater than 1 atm for the treatment of various emergent medical conditions including carbon monoxide poisoning.
- Trial name
- NCT04332211
- Testing
- Hyperbaric Oxygen Therapy, Pseudoephedrine 60 MG
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- University of Maryland, Baltimore
Diving Barotrauma
Practice of Scuba Diving by as Many People as Possible: Effect of Medical Assessment to Provide a Suitable and Individualised Framework for Practice (Plongée Santé)
The study focuses on the practice of recreational scuba diving by people who have obtained medical advice for their practice in the hyperbaric and underwater medicine department of the Brest University Hospital.
- Trial name
- Healthy-diving (NCT06555666)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- University Hospital, Brest
Barotrauma, COVID-19
"Barotrauma in Admitted Covid-19 Cases - A Single Center Retrospective Study"
A retrospective study is planned to find out the incidence and association type of respiratory support with barotrauma in Covid-19 cases admitted in Sultan Qaboos University Hospital.
- Trial name
- BARCOV (NCT05216523)
- Where
- Oman
- Volunteers
- 251 people
- Sponsor
- Sultan Qaboos University
Middle Ear Barotrauma
Effects of Hyperbaric Oxygen Therapy on Middle and Inner Ear Functions
The goal of this observational study is to measure the effect of hyperbaric oxygen therapy on middle ear pressure in order to predict the risk factors for middle ear barotrauma also, to assess its effects on hearing functions of…
- Trial name
- HBOT (NCT06209021)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Assiut University
COVID-19, Barotrauma
Barotrauma in Adults With Critical COVID-19
During the pandemic of COVID-19, studies reporting a high incidence of barotrauma, both pneumothorax but also pneumomediastinum, in patients with critical COVID-19.
- Trial name
- NCT05877443
- Testing
- Open system, Non-invasive mechanical ventilation, Invasive mechanical ventilation
- Where
- Sweden
- Volunteers
- 669 people
- Sponsor
- Karolinska Institutet
COVID, Pneumonia, Viral
Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19)
Pneumonia is a recurrent element of COVID-19 infection, it is often associated with development of respiratory failure and patients frequently need various degrees of oxygen therapy up to non invasive ventilation (NIV-CPAP) and…
- Conditions
- COVID, Pneumonia, Viral, Barotrauma, Interstitial Lung Disease
- Trial name
- SequelaeCov (NCT04435327)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Milano Bicocca
Barotrauma Epidemiology
Diver Ear, Nose and Throat Barotrauma Epidemiology
Ear, nose and throat barotrauma are the most frequently encountered accidents during diving. One study related to recreational diving reports that ENT barotrauma concern 10% of dives with experimented divers and 30% with novice…
- Trial name
- BTORL PAF (NCT04647591)
- Testing
- Questionnaires
- Where
- 7 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Ventilator-Induced Lung Injury, Lung Ventilator
Respiratory Mechanics During One-lung Ventilation
Intraoperative lung protective ventilatory strategy has been widely recognized to reduce postoperative pulmonary complications in laparotomy and laparoscopic surgeries.
- Conditions
- Ventilator-Induced Lung Injury, Lung Ventilator, One-lung Ventilation
- Trial name
- NCT04519606
- Testing
- Optimal lung compliance during OLV
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- E-DA Hospital
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Barotrauma, Covid19
Risk Factors for Barotrauma in COVID-19
Barotrauma in mechanical ventilation (MV) is defined as lung damage attributable to the application of high airway pressure and is one of the potential mechanisms of ventilator-induced lung injury (VILI).
- Trial name
- NCT04859881
- Testing
- No intervention
- Where
- Mexico
- Volunteers
- 262 people
- Sponsor
- Hospital General Ajusco Medio
Otitic Barotrauma
Inner and Middle Ear Effects of Hyperbaric Oxygen Thrapy
Audiological evaluation performed to patients on hyperbaric oxygen therapy to see its effects on middle ear pressure
- Trial name
- NCT04186741
- Testing
- Hyperbaric oxygen
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Preterm Infant, BPD - Bronchopulmonary Dysplasia
Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA
Extubation failure is a significant problem in preterm neonates and prolonged intubation is a well-documented risk factor for development of chronic lung disease.
- Conditions
- Preterm Infant, BPD - Bronchopulmonary Dysplasia, Barotrauma
- Trial name
- NCT03242057
- Testing
- NAVA, NIPPV
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida