Clinical trials: Bariatric Surgery Patient
Obesity
Efficacy of Tirzepatide for Weight Management in Patients With Suboptimal Weight Loss After Bariatric Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Many people who have bariatric (weight-loss) surgery do not lose as much weight as expected, or they regain weight over time. This study will test whether a medicine called tirzepatide can help these patients lose more weight and…
- Trial name
- TirBaS (NCT07829198)
- Testing
- Tirzepatide
- Where
- 3 sites in Portugal
- Volunteers
- 70 people
- Sponsor
- Universidade do Porto
Obesity, Bariatric Surgery Candidate
BE Smart - Bariatric Patient - Empowerment in the Preparation and Follow-up of Bariatric Surgery Using the Smartvisit App (BESmart)
Obesity affects an increasing proportion of the population and is associated with numerous comorbidities that cause increased morbidity and mortality. The most effective therapy for morbid obesity is metabolic bariatric surgery.
- Trial name
- BESmart (NCT06061406)
- Testing
- smart visit app
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Wuerzburg University Hospital
Apneic Oxygenation, High-flow Nasal Cannulae
High-flow Nasal Oxygenation in Obese Patients During Apnea
Before going off to sleep patients are given oxygen to saturate blood with oxygen to extend time before a decrease in the level of oxygen in the blood occurs.
- Conditions
- Apneic Oxygenation, High-flow Nasal Cannulae, Bariatric Surgery, Anesthesia Induction
- Trial name
- NCT03195504
- Testing
- HFNC, CON (control)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Obesity, Morbid, Obesity
Study Testing Patient Decision Tools Related to the Risks and Benefits of Weight Loss Surgery
Morbid obesity currently affects more than 11 million US adults and is strongly associated with type 2 diabetes, cancer, cardiovascular disease, and arthritis.
- Conditions
- Obesity, Morbid, Obesity, Decision Aids, Bariatric Surgery
- Trial name
- POINT of View (NCT00666952)
- Testing
- Video Decision Aid, Booklet Decision Aid
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Kaiser Permanente
Obesity, Nausea and Vomiting, Postoperative
The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting
The purpose of this study is to assess the efficacy of Aprepitant + standard antiemetic regimen in reducing postoperative nausea and vomiting after laparoscopic gastric sleeve versus placebo + standard antiemetic regimen
- Trial name
- NCT05772676
- Testing
- Aprepitant
- Where
- Mexico
- Volunteers
- 400 people
- Sponsor
- Hospital General Tlahuac
IDA in the Post-bariatric Surgical Patient
Intravenous (IV) Versus Oral Iron Treatment of Iron Deficiency Anemia in the Post-operative Bariatric Surgical Patient
The aim of the study is to compare two accepted treatments for iron deficiency anemia (oral ferrous sulfate and intravenous ferumoxytol) for efficacy and speed of response in the treatment of iron deficiency anemia (IDA) in the…
- Trial name
- NCT03777514
- Testing
- Ferumoxytol, Ferrous sulfate, Oral vitamin C
- Sponsor
- Johns Hopkins University
Obesity, Morbid, Homocystine; Metabolic Disorder
Homocysteine After Laparoscopic Roux-enY Gastric Bypass
Changes in homocysteine values after bariatric surgery remain controversially discussed. This is the first comprehensive summary to depict timeline changes in homocysteine levels following laparoscopic roux-en-Y gastric bypass.
- Conditions
- Obesity, Morbid, Homocystine; Metabolic Disorder, Bariatric Surgery Candidate, Folate Deficiency
- Trial name
- NCT03489538
- Testing
- laparoscopic long limb roux-en-Y gastric bypass
- Where
- Austria
- Volunteers
- 708 people
- Sponsor
- Medical University of Vienna
Obesity, Bariatric Surgery Candidate
Investigating the Role of Ghrelin in Regulating Appetite and Energy Intake in Patients Following Bariatric Surgery (BARI-INSIGHT)
Bariatric surgery helps patients with severe obesity to lose weight, cures and prevents diseases linked to obesity and reduces the risk of death.
- Conditions
- Obesity, Bariatric Surgery Candidate, Appetitive Behavior
- Trial name
- BARI-INSIGHT (NCT03641417)
- Testing
- GLWL-01
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University College, London
Severe Obesity, Hypoxia
Use of Non-Invasive Positive Pressure Ventilation in Patients With Severe Obesity Undergoing Upper Endoscopy Procedures
The study evaluated the effect of non-invasive positive pressure ventilation (NIPPV) to decrease the incidence of desaturation events in patients with severe obesity undergoing upper endoscopy.
- Trial name
- NCT03529461
- Testing
- Non-invasive positive pressure ventilation through nasal mask, Rescue non-invasive positive pressure ventilation through nasal mask, Secondary rescue maneuvers
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Bristol Hospital
Overweight, Type 2 Diabetes
Quantitative and Qualitative MRI Study of Steatosis in Patients With Metabolic Steatopathy
This is a single centre prospective open-label, non-randomised pilot study whose aim is to identify MRI parameters to better evaluate inflammation and liver fibrosis and thus, in the near future, to avoid the need for liver…
- Conditions
- Overweight, Type 2 Diabetes, Obesity
- Trial name
- IRM Stéatose (NCT02085876)
- Testing
- 2 additional MRI sequences, An additional blood sample
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
COPD Exacerbation, Oxygen Toxicity
Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery
The main objective is to evaluate the FreeO2 device combined with noninvasive respiratory support technique for COPD patients and postoperative bariatric surgery patients.
- Conditions
- COPD Exacerbation, Oxygen Toxicity, Abdominal Obesity, Surgery
- Trial name
- NCT04136717
- Testing
- Washout period, NIV - FreeO2, Nasal High flow Oxygen therapy - FreeO2
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- François Lellouche
Bariatric Surgery Candidate, Nausea, Postoperative
Aromatherapy in Management of Postoperative Nausea in Post-Bariatric Surgery Patients
Determine the effectiveness of peppermint oil aromatherapy in relieving post-operative nausea in the bariatric surgery patient population.
- Trial name
- NCT03130218
- Testing
- Peppermint oil aromatherapy
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Lancaster General Hospital
Obesity, Morbid, Bariatric Surgery
Reducing Sedentary Time in Bariatric: The Take a STAND for Health Study
This research program aims to comprehensively investigate the clinical, physiological, metabolic, and molecular effects of reducing sedentary behavior in post-bariatric patients.
- Trial name
- NCT04517591
- Testing
- The Take a STAND for health
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Obesity, Bariatric Surgery
Impact of Weight Loss After a Bypass Surgery on Renal Hemodynamic Under Stress Conditions
The sympathetic nervous (SNS) and the renin angiotensin aldosterone system (RAS) have a direct impact on renal hemodynamic, hormonal secretion and vasoactive peptide.
- Conditions
- Obesity, Bariatric Surgery, Blood Pressure
- Trial name
- OBBYSS (NCT02218112)
- Testing
- bariatric surgery (gastric bypass)
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Obesity
Testing the Gravitostat in Humans: the Impact of a Weighted Vest in Patients Post Bariatric Surgery on Fat-free Mass Retention and Weight Loss
The mechanisms regulating fat mass homeostasis are incompletely understood although recent animal and human trials would suggest that there is a leptin independent regulatory pathway which may play a role in weight control and…
- Trial name
- NCT04809129
- Testing
- Weighted vest
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Anesthesia, Hypoventilation
Opioid-sparing Versus Sevoflurane Anesthesia on Early Postoperative Hypoventilation in Laparoscopic Bariatric Surgery
Determine the incidence of early post-operative hypoventilation in post-anesthesia care unit (PACU) in patients undergoing laparoscopic bariatric surgery under opioid-sparing compared with sevoflurane-based anesthesia.
- Conditions
- Anesthesia, Hypoventilation, Opioid Use, Bariatric Surgery
- Trial name
- NCT05962671
- Testing
- Opioid-sparing based anesthesia, Sevoflurane-based anesthesia
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Tanta University
Bariatric Surgery, Virtual Reality
The Effect of Virtual Forest Bathing on Bariatric Surgery Patients
This study will be conducted at the General Surgery Clinic of City Hospital in Erzurum between August 2025 and April 2026 using a randomized controlled experimental design.
- Conditions
- Bariatric Surgery, Virtual Reality, Anxiety
- Trial name
- NCT07152054
- Testing
- virtual forest bathing
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Surgery, Post-operative Pain
Laparoscopic Single Incision -Vs- Multiple Incision Gastric Band Surgery
A double blinded randomised control trial comparing the differences between laparoscopic single incision versus multiple port bariatric surgery in morbidly obese patients (BMI>35).
- Conditions
- Surgery, Post-operative Pain, Post-operative Recovery
- Trial name
- SIMIS (NCT01844960)
- Testing
- Single Incision Gastric Band Insertion, Multiple Incision Gastric Band Insertion
- Where
- United Kingdom
- Volunteers
- 44 people
- Sponsor
- King's College Hospital NHS Trust
Bariatric Surgery Candidate
Comparison of STOP-BANG and DES-OSA as Predictive Score for Difficult Intubation.
The DES-OSA Score and the STOP-BANG score were predictive scores for Obstructive Sleep Apnea. This study will compare, among patients scheduled for bariatric surgery, these two scores as predictive scores for a difficult…
- Trial name
- NCT02324946
- Testing
- Mass Screening
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Astes
Obesity, Bariatric Surgery
Does Participation in a Pre-Operative Physical Activity Program Improve Patient Outcomes and Quality of Life?
The primary objective of the study is to determine whether participation in a pre-bariatric surgery physical activity and behavior modification/education program (ENCOURAGEING START) that is tailored to the unique needs of obese…
- Conditions
- Obesity, Bariatric Surgery, Roux-En-Y Gastric Bypass, Exercise
- Trial name
- NCT03049696
- Testing
- ENCOURAGEING START
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba