Clinical trials: Bariatric Surgery Candidate
Diabetes type2, Bariatric Surgery Candidate
Diabetes Reversal and the Subgingival Microbiota
This study seeks to examine the impact of bariatric surgery on oral bacteria in diabetic compared to non-diabetic patients. The purpose of this research study is to examine how diabetes changes the bacteria in the mouth.
- Trial name
- NCT05501093
- Testing
- sample collection
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- University of Pennsylvania
Endometrial Cancer, Atypical Hyperplasia
Bariatric Surgery for Fertility-Sparing Treatment of Atypical Hyperplasia and Grade 1 Cancer of the Endometrium
A growing population of young women with obesity are developing atypical hyperplasia (pre-cancer) and endometrial cancer. Progestin is the standard treatment for women who wish to preserve fertility, but this approach does not…
- Conditions
- Endometrial Cancer, Atypical Hyperplasia, Bariatric Surgery Candidate
- Trial name
- B-FiERCE (NCT04008563)
- Testing
- Bariatric Surgery
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University Health Network, Toronto
Obesity, Bariatric Surgery Candidate
Diet-induced Thermogenesis in Patients With Postoperative Roux-in-Y Gastric Bypass (RYGBP) Weight Regain
Introduction: According to the National Health and Nutrition Examination Survey 2009-2010, 78 million American adults are obese.
- Conditions
- Obesity, Bariatric Surgery Candidate, Protein-energy; Imbalance
- Trial name
- RYGBP (NCT02422212)
- Testing
- patients eat a mixed solid meal
- Where
- 3 sites in Brazil
- Volunteers
- 45 people
- Sponsor
- Silvia Leite Faria
Morbid Obesity, Bariatric Surgery Candidate
Analgesia Management in Bariatric Surgery
Following laparoscopic bariatric surgery, multimodal analgesia is recommended to avoid the adverse effects of opioids by reducing their use.
- Conditions
- Morbid Obesity, Bariatric Surgery Candidate, Pain, Postoperative
- Trial name
- NCT04836819
- Testing
- Lidocain, Ketamine, Dexmedetomidine
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Ondokuz Mayıs University
Bariatric Surgery Candidate, Obesity, Morbid
Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery
Obesity is a complex chronic disease, in which both genetic and environmental factors are involved, that shows a great heterogeneity in the response to different weight loss programs.
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Genetic Predisposition, Metabolic Syndrome
- Trial name
- GENBASU (NCT06226194)
- Where
- Spain
- Volunteers
- 6,966 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
Diabetes Mellitus, Bariatric Surgery Candidate
Glycemic Index Variations In the Early Period Following Bariatric Surgery
The diverse community of gut microbes commonly referred to as the 'gut microbiome', is increasingly suggested to play significant roles in health and disease, and to affect even distant non-GI organs by metabolite signaling.
- Trial name
- NCT04263168
- Testing
- Continuous Glucose monitoring in the perioperative period
- Where
- Israel
- Sponsor
- Sheba Medical Center
Weight Loss, Bariatric Surgery Candidate
Liraglutide Effectiveness in Preoperative Weight-loss for Bariatric-metabolic Surgery
Severe obesity is associated with considerable reduction of wellbeing and life expectancy. People living with severe obesity tend to die 8 to 10 years earlier.
- Conditions
- Weight Loss, Bariatric Surgery Candidate, Obesity, Morbid
- Trial name
- NCT06201819
- Testing
- Liraglutide injection
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Hospital Civil Juan I. Menchaca
Bariatric Surgery Candidate
Xpan Non-Inferiority Study
A trocar is a surgical instrument with a sharp point and tube and is used to create endoscopic access in the abdomen or chest where endoscopic instruments can be entered \& used in minimally invasive surgical procedures.
- Trial name
- NCT07385690
- Testing
- Xpan Trocar System, Standard of Care (Non-expanding Trocar)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- West Virginia University
Bariatric Surgery Candidate
Endoscopic Management Of Refractory Gastro-cutaneous Fistula After Laparoscopic Sleeve Gastrectomy l
This study included patients who were admitted to investigators' center to do laparoscopic sleeve gastrectomy and complicated by gastro-cutaneous fistula . Cases were collected in the period from December 2019 to march 2021.
- Trial name
- NCT04879667
- Testing
- endoscopic management of gastrocutaneous fistula after laparoscopic sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Obesity, Obesity, Morbid
Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy
Rapid metabolic improvements seen with sleeve gastrectomy are likely a result of changes in gastric origin. The gastric mucosa is an endocrine organ that regulates satiation pathways and is a complex regulator of food intake as…
- Conditions
- Obesity, Obesity, Morbid, Obesity; Endocrine, Bariatric Surgery Candidate
- Trial name
- GMD (NCT03526263)
- Testing
- Gastric mucosal devitalization
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Obesity, Bariatric Surgery Candidate
Impact of Bariatric Surgery in Obese Patients With and Without Obstructive Sleep Apnea Syndrome
It has been shown to date that obesity is associated with increased mortality and that weight loss significantly improves cardiovascular risk factors.
- Conditions
- Obesity, Bariatric Surgery Candidate, Apnea, Obstructive
- Trial name
- COLOSS (NCT04179188)
- Testing
- Bariatric surgery
- Where
- France
- Volunteers
- 400 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Bariatric Surgery Candidate
Physical Activity and Bariatric Surgery
Bariatric surgery indeed leads to significant weight loss, reduces mortality risk, obesity-associated comorbidities (Wolfe et al., 2016) and improves functional physical abilities (Herring et al., 2016).
- Trial name
- ACTIBARIA (NCT05050968)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Bariatric Surgery Candidate
Food Preferences After Bariatric Surgery (BariaTaste 3)
Bariatric surgery is currently considered the most effective treatment for achieving significant, sustained weight loss and reducing comorbidities associated with obesity.
- Trial name
- BariaTaste3 (NCT03911115)
- Testing
- Food preference questionnaire
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Hospices Civils de Lyon
Bariatric Surgery Candidate, Bariatric Surgical Procedure
Fat Taste Sensory Study
Fat is the most energy dense macronutrient and consuming fat has been positively correlated to obesity. Individuals afflicted with obesity crave fat more frequently, have a higher preference for fatty taste, and consume a higher…
- Trial name
- FaTSS (NCT03540693)
- Testing
- RYGB, SG, LAGB
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
General Laparoscopic Surgery Candidate, Bariatric Laparoscopic Surgery Candidate
Usability and Performance Evaluation of the AutoLap System - a Feasibility Study
The main objectives of this study are to evaluate the ease of use and performance of the AutoLap system compared to human camera holder during general and bariatric laparoscopic surgeries.
- Trial name
- NCT02346552
- Testing
- AutoLap
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- M.S.T. Medical Surgery Technology LTD.
Obesity, Type2 Diabetes
Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
The objective of the analysis was to evaluate the relationship between bariatric surgery and cardiovascular outcomes in obese patients with type 2 diabetes.
- Conditions
- Obesity, Type2 Diabetes, Bariatric Surgery Candidate
- Trial name
- NCT03955952
- Testing
- Bariatric Surgery
- Where
- United States
- Volunteers
- 91,700 people
- Sponsor
- The Cleveland Clinic
Diabetes, Insulin Resistance
Physiologic and Functional Adaptations of Insulin Sensitive Tissues
The long-term goal is to understand the mechanisms of intestinal nutrient sensing and signal relays to insulin sensitive tissues (adipose, skeletal muscle, liver) in humans.
- Conditions
- Diabetes, Insulin Resistance, Obesity, Bariatric Surgery Candidate
- Trial name
- NCT03407833
- Testing
- Endoscopy biopsy, Surgical biopsy, Mixed-meal tolerance test
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Vanderbilt University Medical Center
Bariatric Surgery Candidate, Mechanical Ventilation
Comparison of Two Mechanical Ventilation Modes on Oxygenisation
Comparison the effect of two different mechanical ventilation modes on tissue oxygenization.
- Conditions
- Bariatric Surgery Candidate, Mechanical Ventilation, Hypoxia, Tissue Damage
- Trial name
- NCT04389047
- Volunteers
- 30 people
- Sponsor
- Bagcilar Training and Research Hospital
Anesthesia and Analgesia, Magnesium Sulfate
Magnesium Sulfate in Bariatric Surgery
Weight loss surgery, also known as bariatric surgery, has been around since the 1950s and since its inception has been shown to successfully achieve significant and sustainable weight loss in a large number of patients who…
- Conditions
- Anesthesia and Analgesia, Magnesium Sulfate, Bariatric Surgery Candidate
- Trial name
- MgSObs (NCT05843812)
- Testing
- Magnesium Sulfate 10 MG/ML
- Where
- Mexico
- Volunteers
- 104 people
- Sponsor
- Instituto Mexicano del Seguro Social
Obesity, Obesity, Morbid
Endoscopic Metabolic and Bariatric Therapies
This is a prospective collection of data from adult patients who have had an endoscopic metabolic and bariatric endoscopy procedure (EMBT) for primary or revision surgical procedures for obesity.
- Conditions
- Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate
- Trial name
- EMBTs (NCT05725967)
- Testing
- Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Christopher C. Thompson, MD, MSc