Clinical trials: BPH
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the Prostate
Holmium laser enucleation of the prostate (HoLEP) is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-HOLEP (NCT07892599)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Ahmed Ebrahim Zahran
Benign Prostatic Hyperplasia (BPH)
To Linguistically and Psychometrically Validate the Hong Kong Chinese Version of the BPH 3-item Questionnaire
This study is to linguistically and psychometrically validate the translated and culturally adapted Hong Kong Chinese version of the BPH 3-item questionnaire.
- Trial name
- NCT05785286
- Testing
- BPH 3-item questionnaire
- Where
- 2 sites in Hong Kong
- Volunteers
- 66 people
- Sponsor
- Chinese University of Hong Kong
Benign Prostatic Hyperplasia (BPH)
The FLOW Registry.
The purpose of this study is to create a database and prospective registry for data collection on patients with benign prostatic hyperplasia undergoing Aquablation of the prostate.
- Trial name
- NCT07430423
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Chicago
Benign Prostatic Hyperplasia (BPH)
To Establish the Safety and Effectiveness of the ALPFA GRAIL PFA System for Treating Symptomatic Benign Prostate Hyperplasia (BPH) Also Known as an Enlarged Prostate.
The main goal of this study is to evaluate the ALPFA GRAIL™ Pulsed Field Ablation (PFA) System for treatment of enlarged prostate (BPH) symptoms.
- Trial name
- REBOUND (NCT07592299)
- Testing
- Treatment Device: The ALPFA Medical (ALPFA) GRAIL™ Pulsed Field Ablation (PFA) System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- ALPFA Medical
Benign Prostate Hypertrophy(BPH)
Orientation Video Training Administered at Different Times to Patients Undergoing Prostate Surgery on Postoperative Pain and Anxiety (Video Training)
This study aims to evaluate the effect of operating room orientation video education delivered at different time points on postoperative pain and state anxiety in patients undergoing surgery for benign prostatic hyperplasia.
- Trial name
- NCT07778355
- Testing
- Operating Room Orientation Video Education, Routine Preoperative Information
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Ondokuz Mayıs University
Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms
Emsella for Reducing tSUI After HOLEP
This study aims to investigate the effectiveness of the Emsella chair treatments at different timepoints. Before and after the holmium laser enucleation of the prostate (HoLEP).
- Conditions
- Benign Prostatic Hyperplasia, Enlarged Prostate With Lower Urinary Tract Symptoms, Enlarged Prostate (BPH)
- Trial name
- NCT07580404
- Testing
- Emsella chair
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Enlarged Prostate (BPH), Benign Prostatic Hyperplasia
Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.
- Trial name
- NCT07632742
- Testing
- Magneto 150 holmium laser, Moses 2.0 holmium laser
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Northwestern University
BPH, Lower Urinary Tract Symptoms
HoLEP Sexual Survivorship
The objective of this study is to evaluate how sexual function, ejaculatory function, and overall sexual satisfaction change following Holmium Laser Enucleation of the Prostate (HoLEP).
- Trial name
- NCT07660068
- Testing
- Telephone Interview, Questionnaires over the span of 24 months
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Northwestern University
Benign Prostatic Hyperplasia (BPH)
REZŪM vs. Dual Drug Therapy for Symptomatic Benign Prostatic Hyperplasia in Sexually Active Men
The study objective is to compare water vapor thermotherapy with the REZŪM™ System to dual drug therapy for the treatment of symptomatic benign prostatic hyperplasia refractory to alpha-blocker monotherapy in sexually active men.
- Trial name
- VAPEUR (NCT04838769)
- Testing
- REZŪM, alpha blocker and 5-alpha reductase inhibitor
- Where
- 21 sites in Australia, France
- Volunteers
- 155 people
- Sponsor
- Boston Scientific Corporation
Benign Prostate Hypertrophy(BPH), Renal Calculi
Stone and Laser Therapies Post-Market Study (SALT)
The objective of the SALT Study is to obtain post-market safety and device performance data for Boston Scientific's Stone and BPH study devices used during a diagnostic and/or therapeutic urinary tract procedure (e.g.…
- Conditions
- Benign Prostate Hypertrophy(BPH), Renal Calculi, Ureteral Stones, Kidney Stones, Calculi, Urinary
- Trial name
- SALT (NCT06982235)
- Testing
- Ureteroscope system, Laser system
- Where
- 5 sites in United States
- Volunteers
- 238 people
- Sponsor
- Boston Scientific Corporation
Benign Prostatic Hyperplasia (BPH)
Laser Ablation a Salvage Treatment for Obstructive Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition affecting aging men, often leading to lower urinary tract symptoms (LUTS).
- Trial name
- ECHOLASER (NCT07016620)
- Testing
- Transperineal Laser Ablation (TPLA)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Bladder Outlet Obstruction, BPH
High Intensity Focused Ultrasound (HIFU) Ablation for Treatment of Prostate Tissue in Bladder Outlet Obstruction
Objectives: To assess the efficacy of HIFU therapy for benign prostatic tissue ablation in patients with lower urinary tract symptoms (LUTS) due to bladder outlet obstruction (BOO) that caused by Benign prostatic hyperplasia…
- Trial name
- HIFU for BOO (NCT07194187)
- Testing
- High Intensity Focused Ultrasound
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
BPH (Benign Prostatic Hyperplasia)
HoLEP-ThuLEP - Comparing Lasers for BPH Surgery
Benign prostatic hyperplasia (BPH) is a very common condition in older men. As the prostate enlarges, it can press on the urethra and make urination difficult.
- Trial name
- HOT (NCT07565961)
- Testing
- Thulium Laser Enucleation of the Prostate (ThuLEP), Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
BPH With Symptomatic Lower Urinary Tract Symptoms, BPH With Urinary Obstruction
Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate
Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy.
- Trial name
- NCT07187180
- Testing
- holmium laser, pulsed thulium laser
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Smita De
Benign Prostatic Hyperplasia (BPH)
Post-Market Study to Assess iTind Safety in Comparison to UroLift
The study objective is to evaluate the efficacy and safety of the iTind device compared to UroLift.
- Trial name
- MT-08 (NCT04757116)
- Testing
- iTind, UroLift
- Where
- 19 sites in United States, United Kingdom
- Volunteers
- 256 people
- Sponsor
- Olympus Corporation of the Americas
Benign Prostate Hypertrophy(BPH)
Suprapubic Cystostomy as an Adjunct to Monopolar Transurethral Enucleation of the Prostate
SPC use has previously been evaluated in monopolar transurethral enucleation and resection of the prostate (M-TUERP) compared with bipolar TURP [10].
- Trial name
- NCT07841964
- Testing
- Monopolar transurethral enucleation of the prostate without suprapubic cystostomy, Monopolar transurethral enucleation of the prostate with suprapubic cystostomy
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Beni-Suef University
Moderate-to-severe Benign Prostatic Hyperplasia (BPH)
Bioequivalence Study of AJU-G721 and G721R in Healthy Adult Volunteers Under Fasting Conditions
To evaluate and compare the safety and pharmacokinetic profiles of "AJU-G721" (test drug) and "G721R" (reference drug) in healthy adult male subjects.
- Trial name
- NCT07643220
- Testing
- Test Drug, Reference Drug
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
BPH/LUTS/Sexual Functions
Long Term Evaluation of Ejaculatory Hood Preserving GreenLight Laser Photoselective Vaporization of the Prostate
long term evaluation of ejaculation preserving laser prostatectomy for BPH patients
- Trial name
- EJHP-GLPVP (NCT07819032)
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Mansoura University
BPH (Benign Prostatic Hyperplasia)
Standard Versus Double Alpha Blockers Treatment for Symptomatic Benign Prostatic Obstruction
Failed medical treatment to alleviate LUTS and AUR is an indication for intervention, some trials were published elucidating the possible use of standard dose tamsulosin and silodosin and double dose tamsulosin but to the best of…
- Trial name
- NCT07815379
- Testing
- alpha blocker monotherapy Tamsulosin, alpha blockers Tamsulosin and Silodosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
BPH/LUTS/Sexual Functions
Standard HoLEP vs Virtual Basket HoLEP for Treatment of BPH
We aimed to assess impart of VB-HoLEP in management of BPH
- Trial name
- VB-HOLEP (NCT07816484)
- Testing
- standard Holmium laser enucleation of the prostate, Virtual basket Holmium laser enucleation of the prostate
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Mansoura University