Clinical trials: BOWEL PREPARATION (BOWEL CLEANSING)
Bowel Preparation for Colonoscopy
Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing
Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy.
- Trial name
- NCT06728839
- Testing
- 1L PEG + 50g magnesium sulfate, 3L PEG, 4L PEG
- Volunteers
- 1,329 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
POCD - Postoperative Cognitive Dysfunction, Mechanical Bowel Preparation
Investigation of the Effect of Preoperative Bowel Cleansing on Postoperative Cognitive Impairment
Cognitive impairment has been reported up to 54 % after colorectal surgeries. Mechanical bowel cleansing means that a system called the second brain in the body, which includes a wide variety of genetic and neuronal structures…
- Trial name
- NCT05942404
- Testing
- mechanical bowel preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- TC Erciyes University
Colonoscopy, Bowel Preparation
Evaluation of an Oral Sodium Sulfate Solution for Patients With Prior Difficult or Incomplete Cleansing
This case series aims to evaluate the effectiveness and tolerability of Oral Sulfate Solution (OSS) in patients who had previously experienced poor colonoscopy preparation.
- Trial name
- OSS (NCT06051955)
- Testing
- oral sodium sulfate
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Lawrence Charles Hookey
Elective Colonoscopy
Efficacy and Safety of mAnnitol in Bowel Preparation During Elective Colonoscopy and Comparison With Moviprep®
The purpose of this dose finding/comparative efficacy study is to first single out the most appropriate dose of mannitol for bowel preparation (phase II) and, subsequently, demonstrate the non-inferiority of the efficacy of…
- Trial name
- SATISFACTION (NCT04759885)
- Testing
- Phase II: NTC015 low dose, Phase II: NTC015 medium dose, Phase II: NTC015 high dose
- Where
- 35 sites in France, Germany and 2 more
- Volunteers
- 886 people
- Sponsor
- NTC srl
Bowel Preparation for Colonoscopy
Evaluation of the Quality of Bowel Cleansing in a Real Clinical Practice Setting
Publications of the use of bowel cleansers in usual clinical practice are lacking. Patient adherence to investigational products increases in the context of clinical trials.
- Trial name
- CALICOL (NCT02839824)
- Testing
- Bowel preparation
- Where
- Spain
- Volunteers
- 412 people
- Sponsor
- Casen Recordati S.L.
Renal Impairment, Adverse Effects of Medical Drugs
Bowel Cleansing With Renal Impairment
Bowel preparation for colonoscopy requires the administration of large amounts of fluids that can cause fluid and electrolyte disturbances and volume overload, especially in patients with advanced renal failure.
- Trial name
- BC-RIMP (NCT05349851)
- Testing
- Follow-up with blood and urine analysis
- Where
- 2 sites in Spain
- Volunteers
- 237 people
- Sponsor
- Marco Antonio Alvarez Gonzalez
Colorectal Neoplasms
Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy
Polyethylene glycol is the gold standard of bowel preparation for colonoscopy. The most important disadvantage is high volume of this preparation.
- Trial name
- NCT03242369
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Military University Hospital, Prague
Bowel Preparation Solution
PEG-Asc Vs. SPMC for Bowel Preparation in Capsule-based Procedures
This clinical research study is designed to find out which of two different types of bowel preparation works best for people undergoing capsule-based endoscopy procedures.
- Trial name
- NCT07206329
- Testing
- Polyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC)
- Where
- Portugal
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Colon Cleansing
PMC Split Preparation for Colon Cleansing
This is an endoscopist-blinded, prospective, multicenter study involving adult outpatients aiming at evaluating whether sodium picosulphate/magnesium citrate split dosing is associated to higher efficacy and acceptability in…
- Trial name
- MAGIC-P (NCT01909219)
- Testing
- Sodium picosulphate/magnesium Citrate
- Where
- 2 sites in Italy
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Luigi Sacco University Hospital
Preparation for Colonoscopy
Safety and Efficacy of High Dose Bowel Preparation Solutions for Patients With Difficult To Clean Colons For Colonoscopy
The purpose of this study is to document the safety and effectiveness of high doses of liquids to clean the colon for colonoscopy in patients who had a previous colonoscopy with a poorly cleaned colon.
- Trial name
- NCT02661750
- Testing
- Bowel Preparation
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Gastroenterology Services, Ltd.
Bowel Preparation
Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic…
- Trial name
- NCT05137145
- Testing
- Linaclotide, Compound Polyethylene Glycol Electrolyte Powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Bowel Preparation Before Colonoscopy
A Trial to Evaluate the Efficacy and Safety of PMF104 Compared to a Conventional PEG-electrolyte Solution in Children
A randomised, single-blind, active controlled, multi-centre trial to evaluate the efficacy, safety, tolerability, acceptability and palatability of PMF104 compared to a conventional PEG-electrolyte solution in paediatric subjects…
- Trial name
- NCT03106922
- Testing
- PMF104, Klean-prep
- Where
- 9 sites in Belgium, France and 1 more
- Volunteers
- 430 people
- Sponsor
- Alfasigma S.p.A.
Colonoscopy, Bowel Cleansing
The Effect of pH Value of Water Consumed During Bowel Preparation Before Colonoscopy on Colon Cleansing
Colonoscopy is a commonly used minimally invasive method for evaluating the lower gastrointestinal tract. The quality of colonoscopy is assessed by factors such as cecal intubation rate and adenoma detection rate, both of which…
- Conditions
- Colonoscopy, Bowel Cleansing, Water Intake, pH
- Trial name
- NCT07669116
- Testing
- Colon preparation for colonoscopy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Sinan Ömeroğlu, MD
Bowel Preparation Scale, the Amount of Air Bubble
Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy
In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 3L PEG before colonoscopy.
- Conditions
- Bowel Preparation Scale, the Amount of Air Bubble, Adenoma Detection Rate
- Trial name
- NCT03352700
- Testing
- 3L PEG, 3L PEG+Dyclonine Hydrochloride Mucilage
- Where
- China
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Bowel Preparation
Investigation of PicoPrep Versus HalfLytely for Bowel Preparation for Colonoscopy - Split Dose PicoPrep
Subjects undergoing an elective complete colonoscopy will randomly receive either PicoPrep: 2-sachets for oral solution in two divided doses given a night before (first dose - sachet) and approximately 5 hours prior to procedure…
- Trial name
- NCT01073930
- Testing
- PicoPrep, HalfLytely, bisacodyl
- Where
- 9 sites in United States
- Volunteers
- 608 people
- Sponsor
- Ferring Pharmaceuticals
Colorectal Cancer
Efficacy and Tolerability of Suprep With and Without Simethicone for Routine Colonoscopy for Colorectal Cancer Screening
The purpose of this study is to investigate Suprep bowel preparation, with and without the anti-gas medication simethicone, in terms of efficacy and patient tolerability in the preparation of patients undergoing routine…
- Trial name
- NCT02523911
- Testing
- Simethicone, sodium sulfate/potassium sulfate/magnesium sulfate solution
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MercyOne Des Moines Medical Center
BOWEL PREPARATION (BOWEL CLEANSING)
Patients Judging Bowel Preparation by Using SMARTPHONE Application
High-quality bowel preparation is a prerequisite for colonoscopy. Few studies have evaluated visual aids as a means of improving the quality of bowel preparation.
- Trial name
- BPBUSA (NCT01937819)
- Testing
- SMART arm
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inje University
Bowel Cleansing Quality, Predictors
A Predictive Model for Inadequate Bowel Preparation Before Colonoscopy: Development and Validation
About 30% of patients were reported to suffer inadequate bowel preparation.
- Conditions
- Bowel Cleansing Quality, Predictors, Colonoscopy, Boston Bowel Preparation Scale
- Trial name
- NCT02726893
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,504 people
- Sponsor
- Shandong University
Colorectal Cancer, Colonoscopy Preparation
The Effect of Nurse Process on Bowel Cleansing
Colonoscopy is still the gold standard method for the diagnosis and treatment of colon cancers. Preparation for colonoscopy is a complex processa (eg.
- Conditions
- Colorectal Cancer, Colonoscopy Preparation, Boston Bowel Preparation Scale, Nursing
- Trial name
- NCT06453655
- Testing
- Nursing Process
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Capsule Endoscopy, Inflammatory Bowel Diseases
Differences in Preparation for Small Bowel Capsule Endoscopy
The introduction of video capsule endoscopy in 2000 has provided a convenient and minimally invasive imaging method for the whole small bowel.
- Conditions
- Capsule Endoscopy, Inflammatory Bowel Diseases, Celiac Disease
- Trial name
- NCT03351972
- Testing
- Klean Prep, Clear liquids only
- Where
- 2 sites in Canada, United Kingdom
- Volunteers
- 230 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust