Clinical trials: BD
Advanced Solid Tumours
The Pharmacokinetics and Safety of Olaparib Alone and With Paclitaxel in Chinese Patients With Advanced Solid Tumour.
This is a 2 parts phase I, open label trial of olaparib monotherapy and olaparib in combination with paclitaxel in patients with solid tumours.
- Trial name
- NCT02430311
- Testing
- Olaparib, Paclitaxel
- Where
- 3 sites in China
- Volunteers
- 36 people
- Sponsor
- AstraZeneca
Acquired Immunodeficiency Syndrome
Accuracy Evaluation of the BD FACS Presto System
The enumeration of T lymphocytes positive for the CD4 antigen is used to determine the immune status of patients with, or suspected of developing, immune deficiencies such as AIDS.
- Trial name
- NCT02396355
- Testing
- Investigational BD FACSPresto System, BD FACSCalibur flow cytometer, Sysmex hematology analyzer KX-21
- Where
- 6 sites in United States, India and 2 more
- Volunteers
- 583 people
- Sponsor
- Becton, Dickinson and Company
Bipolar Disorder (BD)
Body Weight Changes After Switching to Lurasidone for Antipsychotic-induced Weight Gain in Bipolar Disorder
Study Objective: To evaluate the treatment effectiveness and safety by analyzing prescription patterns in a routine clinical practice setting and observing changes in clinical indicators (weight, BMI, HAM-D, CGI-S, CGI-I) among…
- Trial name
- NCT07834112
- Testing
- Lurasidone
- Where
- South Korea
- Volunteers
- 155 people
- Sponsor
- Dong-Wook Kim
Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C)
"Efficacy and Safety of Linaclotide in Chronic Constipation"
Goal of this study is to evaluate the efficacy and safety of two different doses of Linaclotide in improving bowel function and patient-reported outcomes among Bangladeshi patients with chronic constipation for 8 weeks along with…
- Conditions
- Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C), Chronic Constipation, CIC
- Trial name
- LIN-CC-BD (NCT07431957)
- Testing
- Linaclotide 72 micrograms, Linaclotide 145 micrograms
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Md Mehedi Shahriar
Bipolar Disorder
Personal Adherence Evaluation of Medication Use for Adult Bipolar Disorder Patients
This study will attempt to increase understanding of why bipolar disorder patients do or do not take their medications by conducting in-depth interviews with them.
- Trial name
- NCT00763581
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Western Reserve University
Bipolar Disorder
Functional Remediation for Older Adults With Bipolar Disorder
Bipolar Disorder (BD) is a chronic and severe mental illness characterized by the emergence of alternating mood episodes which range from extreme depression to manic states.
- Trial name
- FROA-BD (NCT05186337)
- Testing
- FROA-BD programme
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Consorcio Centro de Investigación Biomédica en Red (CIBER)
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Adult Nocturnal Enuresis, Urinary Incontinence (UI)
This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.
This post-market study will assess the performance of and user experience with the PureWick™ System in a home setting. The study will also observe safety of the study device and collect information from participants about their…
- Trial name
- PUREST (NCT06666426)
- Testing
- PureWick System, Hollister Female Urinary Pouch External Collection Device
- Where
- 15 sites in United States
- Volunteers
- 171 people
- Sponsor
- C. R. Bard
Bipolar Disorder (BD), Depression - Major Depressive Disorder
Epigenetic Enhancement of Cognitive Training in Aging Mood and Schizophrenia Spectrum Disorder Populations
The aim of this clinical trial is to investigate the effects of a three-week virtual reality-based cognitive remediation training (VR-CRT) programme in combination with daily intake of a histone deacetylase inhibitor (HDACi)…
- Conditions
- Bipolar Disorder (BD), Depression - Major Depressive Disorder, Cognitive Impairment, Schizophrenia Disorders
- Trial name
- EPIC (NCT07404085)
- Testing
- Virtual Reality-based cognitive remediation therapy (VR-CRT), Virtual Reality-based control treatment (VR-CT), HDACi butyrate
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Type II Diabetes
To Evaluate 24-hr Glucose After OD vs BD AZD1656
The purpose of this study is to compare the 24-hour glucose profiles in diabetic patients treated with metformin following once daily and twice daily oral dosing
- Trial name
- NCT00819884
- Testing
- AZD1656
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- AstraZeneca
Bipolar Disorder (BD)
LRFN5 and OLFM4 in Bipolar Disorder
This cross-sectional observational case-control study evaluated serum levels of leucine-rich repeat and fibronectin type III domain-containing protein 5 (LRFN5) and olfactomedin-4 (OLFM4) in subjects with bipolar disorder (BD)…
- Trial name
- NCT07434414
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Bipolar Disorder (BD)
The PEDAL Intervention - Reducing Affective Lability in Bipolar Disorder
PEDAL is a group-based intervention for patients with bipolar disorder that builds on the traditional group psychoeducational program (GPP) by adding digital tools and specific strategies to help manage rapid fluctuations between…
- Trial name
- PEDAL (NCT07239778)
- Testing
- Traditional group psychoeducation for bipolar disorder, Group psychoeducation with digital elements and focus on affective lability
- Where
- 4 sites in Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Diabetes, Diabetes Mellitus, Type 1
Comparison of Glycemic Control Achieved With 2 Different Needles
This trial is conducted in the United States of America (USA). The aim of this trial is to investigate if a 31 gauge x 6 mm needle will provide comparable blood glucose control to the 29 gauge x 12.7 mm needle in obese subjects…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Delivery Systems
- Trial name
- NCT00572052
- Testing
- NovoFine® needle 6 mm, Ultra-Fine needle 12.7 mm
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Novo Nordisk A/S
Diabetes
Comparative User Experiences With BD Nano™ PRO 32G Extra Thin Wall Pen Needle vs the Terumo Nanopass® 34G Pen Needle
This is a subject single blinded, block randomized, prospective, single-visit, multi-center study to compare user experiences with BD Nano™ PRO pen needle vs. the thinner commercially available Terumo Nanopass® pen needle.
- Trial name
- NCT03878745
- Testing
- Terumo Nanopass® 34G pen needle, BD Nano™ PRO 32G pen needle
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Becton, Dickinson and Company
Treatment Adherence and Compliance, Severe Mental Disorders
Medication Adherence in Severe Mental Illness: a Promotion Program
People living with serious mental illnesses such as schizophrenia and bipolar disorder often need long-term medication to stay well.
- Conditions
- Treatment Adherence and Compliance, Severe Mental Disorders, Bipolar Disorder (BD), Schizophrenia Disorder
- Trial name
- ADHERA (NCT07445802)
- Testing
- Telehealth Psychoeducational Adherence Program
- Volunteers
- 1,640 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Patch Electrode
UCon is a medical device for treating the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behavior of the bladder/bowel musculature e.g.…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Nocturia, Urinary Frequency More Than Once at Night
- Trial name
- NCT06754189
- Testing
- Time Limited stimulation
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- InnoCon Medical
Schizophrenia Disorder, Schizoaffective Disorder
Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization
This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance…
- Conditions
- Schizophrenia Disorder, Schizoaffective Disorder, Bipolar Disorder (BD), Substance Use Disorder (SUD)
- Trial name
- NCT07130500
- Testing
- Financial incentives for adherence to long-acting injectable medication, Standard of care with monthly surveys
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University
Bipolar Disorder (BD), Schizophrenia Spectrum Disorders (SSD)
Virtual Reality-Based Cognitive Remediation in Schizophrenia and Bipolar Disorder
This randomized controlled trial aims to evaluate the effectiveness of a virtual reality-based cognitive remediation (VRCR) intervention in improving cognitive performance and psychosocial functioning in individuals with…
- Trial name
- NCT07632989
- Testing
- Virtual Reality Cognitive Remediation (VRCR), Treatment as Usual (TAU)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Università degli Studi di Brescia
Type 2 Diabetes Mellitus (T2DM)
Comparison of Thrice-Daily Premixed Human Insulin With Basal-Bolus Therapy Among Patients With Poorly Controlled Type 2 Diabetes Mellitus
The goal of this cross-over study is to learn if thrice-daily (TDS) premixed human insulin (PHI) is as useful as basal-bolus (BB) therapy as an intensification treatment in people with poorly controlled type 2 diabetes mellitus…
- Trial name
- NCT06855615
- Testing
- Mixtard® 30 TDS, Insulatard® once daily and thrice daily prandial Actrapid®
- Where
- Malaysia
- Volunteers
- 44 people
- Sponsor
- Hospital Sultanah Aminah Johor Bahru
Bipolar I Disorder
Efficacy of Combined Treatment for Young Bipolar I Disorder
The purpose of this study is to determine the efficacy of the combination of lithium and carbamazepine compared with lithium and valproate treating young bipolar patients.
- Trial name
- LICAVAL (NCT00976794)
- Testing
- lithium plus carbamazepine, lithium plus valproate
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo