Clinical trials: Awake Intubation
Difficult Mask Ventilation, Difficult Intubation
Effectiveness of C-MAC Video-stylet Versus Fiberoptic Bronchoscope for Awake Intubation
C-MAC- Video Stylet is a completely new type of video endoscope. It combines the advantages of both rigid and flexible intubation endoscopes.
- Trial name
- NCT04759287
- Testing
- C-MAC VS, flexible fibreoptic bronchoscope
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- rehab zayed
Sedation, Intubation
Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation
The purpose of this study is to compare the sedation effect of dexmedetomidine and propofol when they are both combined with midazolam and remifentanil during awake endotracheal intubation.
- Trial name
- NCT04753515
- Testing
- dexmedetomidine combined with midazolam and remifentanil., propofol combined with midazolam and remifentanil.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Difficult or Failed Intubation, Sedative Adverse Reaction
Comparison of Remifentanil With a Combination of Remimazolam and Dexmedetomidine for Awake Tracheal Intubation
Awake fiberoptic intubation (AFOI) requires airway surface anesthesia to inhibit pharyngeal reflex, glottis closure reflex, and cough reflex.
- Trial name
- NCT06581731
- Testing
- remimazolam combined with remifentanil, dexmedetomidine combined with remifentanil
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Awake Fiberoptic Intubation
Dexmedetomidine Versus Ketamine-midazolam Sedation in Awake Fiberoptic Intubation in Suspected Difficult Airway
The goal of this clinical trial is to obtain the optimal patient's comfort and cooperation during awake fiberoptic intubation with prototype device.
- Trial name
- NCT06946212
- Testing
- Dexmedetomidine, Ketamine plus Midazolam
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Zagazig University
Tracheal Intubation, Difficult Airway
Evaluation of the Single Use Flexible Optical Scope Versus Multiple Use Flexible Optical Scopes for Intubation
The study is in two parts Part one of the study describes the use of the new single-use flexible video-scope for intubation of patients with predicted normal airways.
- Trial name
- NCT01100957
- Testing
- tracheal intubation with a single use flexible videoscope
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intubation; Difficult
Sedation Effect of Dexmedetomidine Versus Remifentanil to Fibreoptic Intubation
The purpose of this study is to compare the sedation effect of dexmedetomidine and target controlled remifentanil for awake nasotracheal fibreoptic intubation in patients undergoing oral maxillofacial surgery.
- Trial name
- NCT01474213
- Testing
- dexmedetomidine group, remifentanil group
- Where
- 2 sites in China
- Volunteers
- 42 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Awake Fiberoptic Intubation, Difficult Airway
Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation
The purpose of this study is to examine the effects of different sedation drugs used for the awake fiberoptic intubation procedure.
- Trial name
- NCT05736198
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Illinois at Chicago
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University
Awake Tracheal Intubation
The Application of Docozine Combined With Sufentanil for Awake Tracheal Intubation
Mortality associated with difficult airway in anesthesia is up to 30%. So, it is urgent to find a safe and effective method for intubation.
- Trial name
- NCT02673723
- Testing
- Docozine, Saline
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
Tracheal Intubation
Infrared Transillumination of the Front of the Neck
Infrared light is applied to the front of the neck of patients for awake flexible optical intubation. The infrared light can be detected by the camera at the tip of the flexible video-bronchoscope.
- Trial name
- IRRIS (NCT03930550)
- Testing
- Tracheal intubation by endoscopy with flexible bronchoscope
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Bariatric Surgery Candidate
Comparison of STOP-BANG and DES-OSA as Predictive Score for Difficult Intubation.
The DES-OSA Score and the STOP-BANG score were predictive scores for Obstructive Sleep Apnea. This study will compare, among patients scheduled for bariatric surgery, these two scores as predictive scores for a difficult…
- Trial name
- NCT02324946
- Testing
- Mass Screening
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Astes
Intubation; Difficult or Failed
Flexible Tip Bougie vs Tube With Stylet for Intubation With Videolaryngoscopy.
Although VLs improve glottic visualization, on many occasions it may not be accompanied by intubation at the first attempt, because the endotracheal tube has to pass a sharp angle to enter the trachea.
- Trial name
- VIFLEXTIPOR (NCT05429125)
- Testing
- Endotracheal Tube with Stylet, Flexible Tip Bougie
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Assessment, Difficult Airway Intubation
Preoperative Assessment of Difficult Laryngoscopy Using Different Videolaryngoscopes
preoperative assessment of difficult airways are the subject of debate. Now, measuring the thyromental distance or evaluating the mallampati score, mandible protrusion or body mass index still not 100% specifically say anything.
- Conditions
- Assessment, Difficult Airway Intubation, Preoperative
- Trial name
- NCT03999866
- Testing
- airtraq, mcgrath mac x-blade, storz c-mac
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kocaeli University
Therapeutic Procedural Complication
Comparing the "sniffing Position" , "Simple Head Extension" and "Neutral Position"
The simple head extension is recommended for optimization of glottic visualization during awake orotracheal intubation whith fiberoptic bronchoscope (FOB) .
- Trial name
- NCT02792855
- Testing
- sniffing Position(place a 7-cm cushion under head ), Simple Head Extension(without cushion)
- Where
- China
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Blood Pressure After Nerve Block, Hemodynamic Stability During Awake Intubation
COMPARISON OF AIRWAY NERVE BLOCK VERSUS NEBULIZED LIDOCAINE ON HEMODYNAMIC RESPONSES DURING AWAKE FIBEROPTIC INTUBATION
This prospective randomized controlled trial aims to compare the effectiveness of airway nerve blocks versus nebulized lidocaine in attenuating hemodynamic responses during awake fiberoptic intubation in adult patients with…
- Trial name
- NCT07627100
- Testing
- Nebulized Lidocaine, Nerve Block
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Mayo Hospital Lahore
Obstructive Sleep Apnea, Difficult Intubation
Airway Ultrasonography Measurements With Cormack Lehane Classification in Patients With OSA
Airway assessment using ultrasonography can provide an additional information in identifying difficult intubation in OSA patients.
- Trial name
- NCT03899519
- Where
- Malaysia
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Obstructive Sleep Apnea, Difficult Intubation
STOP-BANG and Cephalometry in Prediction of Difficult Airway in Patients at Risk of OSA
Incidence of difficult laryngoscopy and difficult intubation are higher among patients with obstructive sleep apnoea (OSA). Precision in making the diagnosis and predicting difficult laryngoscopy preoperatively may help to reduce…
- Trial name
- NCT03105388
- Where
- Malaysia
- Volunteers
- 41 people
- Sponsor
- Universiti Sains Malaysia
Airway Management, Fiberoptic Guided Intubation
Patient Experience of Transoral Versus Transnasal Awake Tracheal Intubation
Airway management problems are key drivers for anesthesia-related adverse events. Awake tracheal intubation using flexible bronchoscopy and preserved spontaneous breathing (ATI:FB) is a recommended technique to manage difficult…
- Conditions
- Airway Management, Fiberoptic Guided Intubation, Patient Experience
- Trial name
- NCT06955884
- Where
- Germany
- Volunteers
- 198 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sleep Quality, Hypoxemic Acute Respiratory Failure
Sleep Quality and Risk of Intubation in Intensive Care Units Patients With Hypoxemic Acute Respiratory Failure
The aim of the study is to evaluate the impact of sleep quality on intubation rate in intensive care units patients with acute respiratory failure
- Conditions
- Sleep Quality, Hypoxemic Acute Respiratory Failure, Intubation Risk
- Trial name
- HIGH SLEEP (NCT02907008)
- Testing
- Polysomnography
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Poitiers University Hospital
Anesthesia Intubation Complication
Comparison of Flexible Fibreoptic Scope With Pentax AWS Videolaryngoscope for Ease of Intubation During Awake Intubation
The purpose of this study is to identify whether Pentax Airway Scope (AWS) videolaryngoscope would be a more effective device compared to flexible fibreoptic scope (FOS) for awake intubation in a difficult airway.
- Trial name
- NCT02614924
- Testing
- Flexible fibreoptic scope, Pentax AWS videolaryngoscope
- Volunteers
- 40 people
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust