Clinical trials: Atrophic Scar
Atrophic Scar
CIC101-02-LT is a Long-term Follow-up Study of Subjects Treated With TRTP-101 and Will Evaluate the Long-term Safety and Efficacy of TRTP-101.
CIC101-02-LT is a long-term follow-up study of subjects treated with TRTP-101 and will evaluate the long-term safety and efficacy of TRTP-101.
- Trial name
- NCT07892937
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CellinCells
Atrophic Acne Scar
Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars
Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited.
- Trial name
- NCT07868445
- Testing
- Fractional co2 laser, Exosomes, Hyaluronic Acid skin booster
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation
Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color
The investigators aim to investigate the efficacy and tolerability of a hybrid non-ablative/ablative laser for acne scarring in skin of color.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation, Laser-Induced Hyperpigmentation
- Trial name
- NCT05362929
- Testing
- Sciton Halo
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Acne, Acne Scars - Mixed Atrophic and Hypertrophic
AVAVA MIRIA General Use
A general protocol to treat a variety of dermatologic conditions and collect patient feedback. Primary outcome is the collection and analysis of patient questionnaires related to the overall experience of the device treatment.
- Conditions
- Acne, Acne Scars - Mixed Atrophic and Hypertrophic, Scars, Wrinkle
- Trial name
- NCT06868615
- Testing
- AVAVA
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Atrophic Acne Scars, Acne Vulgaris
Microneedling With Glycolic Acid or Trichloroacetic Acid for Atrophic Acne Scars
Atrophic acne scars are depressed scars that can remain after acne has healed. Microneedling is a procedure that uses very small needles to create controlled micro-injuries in the skin, which may stimulate collagen production and…
- Trial name
- NCT07797517
- Testing
- Microneedling only, Microneedling with Glycolic Acid 35% Peel, Microneedling with Trichloroacetic Acid 15% Peel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Atrophic Scar
Safety and Efficacy of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and efficacy of a single administration of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT07474467
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CellinCells
Atrophic Acne Scars
ELAPR002f Injectable Gel in the Treatment of Atrophic Acne Scars
Visit the study website https://dawnacnescarstudy.com/ACT for more information. Atrophic acne scars are flat, indented or with an inverted center scars that develop at the endpoint of the normal healing process for acne.
- Trial name
- NCT05995340
- Testing
- ELAPR002f Injectable Gel, Saline Active Control
- Where
- 12 sites in Canada, Germany
- Volunteers
- 157 people
- Sponsor
- AbbVie
Postburn Scars; Posttraumatic Scars, Atrophic Scar
Autologous Nanofat for Treatment of Atrophic Scars
A prospective, randomized, split-scar, within-participant controlled clinical study evaluating the efficacy and safety of a single session of autologous nanofat injection followed by topical silicone gel in the treatment of…
- Conditions
- Postburn Scars; Posttraumatic Scars, Atrophic Scar, Scar
- Trial name
- NCT07763275
- Testing
- Autologous Nanofat Injection, Topical
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Benha University
Atrophic Acne Scars
Comparison of Efficacy of Carbon Dioxide Laser With Subcision Versus Platelet-Rich Plasma Bio-Fillers With Subcision for the Treatment of Atrophic Acne
This randomized controlled trial compared two combined treatment approaches for atrophic acne scars. A total of 100 patients aged 15-45 years were enrolled from the Department of Dermatology, Lahore General Hospital, Lahore, and…
- Trial name
- NCT07752186
- Testing
- Platelet-Rich Plasma Bio-Filler With Subcision, Fractional Carbon Dioxide Laser With Subcision
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Lahore General Hospital
Post-Traumatic Atrophic Scar, Atrophic Scar
Nanofat Injection and Fractional CO2 Laser for Post-Traumatic Atrophic Scars
Post-traumatic atrophic scars are characterized by skin depressions caused by loss of collagen and can lead to cosmetic and psychological concerns.
- Conditions
- Post-Traumatic Atrophic Scar, Atrophic Scar, Scar
- Trial name
- NANOCO2-PTS (NCT07679217)
- Testing
- Autologous Nanofat Injection, Fractional CO2 Laser
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Acne Scars, Acne Scars - Atrophic
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
The objective of this clinical trial is to evaluate the safety and effectiveness of a radiofrequency treatment device for the treatment of atrophic acne scars.
- Conditions
- Acne Scars, Acne Scars - Atrophic, Acne Scar, Acne Scarring
- Trial name
- NCT07620769
- Testing
- Investigational Device with the function deactivated, Investigational Device with the function activated, Control Device
- Where
- 4 sites in China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Melasma, Acne Scars - Mixed Atrophic and Hypertrophic
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized.
- Conditions
- Melasma, Acne Scars - Mixed Atrophic and Hypertrophic, Resurfacing, Rejuvenation
- Trial name
- NCT07036302
- Testing
- 35% TCA combined with croton oil peel, Isolate 35% TCA peel, Erbium-YAG laser
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Jose Roberto Cortelli
Atrophic Acne Scars
Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment.
The aim of this study is to evaluate and compare the efficacy and safety of two different injectable agents combined with subcision for treating rolling acne scars.
- Trial name
- NCT07547956
- Testing
- subcision with PDRN vs HA injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Atrophic Scar
Exososmes in Atrophic Scars Management
Lay Summary (Simple Explanation) Atrophic scars are depressed scars that form when the skin does not heal properly, commonly seen after acne or injuries.
- Trial name
- NCT07569666
- Testing
- Intralesional exosomes, Intralesional Saline
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Zagazig University
Atrophic Acne Scars
Efficacy of Human UC-MSC-derived Exosomes and BM-MSC-derived Exosomes for Atrophic Acne Scar
The goal of this clinical trial is to learn if exosomes from human umbilical cord and bone marrow can improve atrophic acne scars when used after fractional CO₂ laser treatment in adults.
- Trial name
- NCT07510295
- Testing
- Exosomes derived from human umbilical cord and bone marrow mesenchymal stem cells, Hyaluronic Acid (HA)
- Where
- Vietnam
- Volunteers
- 22 people
- Sponsor
- Ngô Anh Tuấn
Acne Scars - Atrophic
Efficacy and Safety of Combined Nanofat Injection With Either Platelet Rich Fibrin or Microneedling Versus Nanofat Injection Alone in the Treatment of Facial Atrophic Post Acne Scars
To compare the efficacy and safety of combined nanofat injection with either platelet rich fibrin or microneedling versus nanofat injection alone in the treatment of facial atrophic post acne scars.
- Trial name
- NCT07471854
- Testing
- nanofat injecion, Platelet rich fibrin, Microneedling
- Volunteers
- 42 people
- Sponsor
- Assiut University
Atrophic Scar
Long-Term Follow-up of Adult With Atorpphic Scars Treated With TRTP-101
CIC101-01-LT is a long-term follow-up study of subjects treated with TRTP-101 and will evaluate the long-term safety and efficacy of TRTP-101.
- Trial name
- NCT06435884
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells
Post-Acne Atrophic Scars, Carbon Dioxide Lasers
PRP Plus Fractional CO₂ Laser for Acne Scars
This randomized controlled trial aims to evaluate whether adding platelet-rich plasma (PRP) to fractional CO₂ laser resurfacing improves the treatment of moderate-to-severe acne scars compared with laser alone.
- Conditions
- Post-Acne Atrophic Scars, Carbon Dioxide Lasers, Platelet-Rich Plasma
- Trial name
- PRPLT (NCT07352215)
- Testing
- Fractional CO₂ Laser + Platelet-Rich Plasma (PRP), Fractional CO₂ Laser Only
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Acne Scars - Atrophic, Wound Healing
Effectiveness of a rhGM-CSF-containing Gel on Promoting Recovery After 1927-nm Fractional Thulium Fiber Laser Treatment of Atrophic Acne Scars.
Atrophic acne scars (AAS) is one of the most common skin sequelae following acne vulgaris. Fractional laser has shown great therapeutic potential in recent years, while there is no standard of wound care after laser resurfacing.
- Trial name
- NCT07305675
- Testing
- rhGM-CSF-containing gel, 1927-nm TFL
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Atrophic Acne Scar
Subcision With CO₂ Laser or PRP vs Subcision Alone in Atrophic Acne Scars
Acne vulgaris is an inflammatory disease of pilosebaceous unit ,leading to different types of scars including atrophic, hypertrophic and keloidal.
- Trial name
- NCT07199608
- Testing
- subcision, subcision+fractional co2 laser, subcision+PRP
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University