Clinical trials: Atrial Fibrillation Ablation Procedure
Persistent Atrial Fibrillation, Atrial Fibrillation, Persistent
Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation
A randomised controlled clinical trial to assess efficacy of convergent ablation with the LARIAT procedure, as compared to standard endocardial catheter ablation in patients with long-standing persistent atrial fibrillation (AF).
- Conditions
- Persistent Atrial Fibrillation, Atrial Fibrillation, Persistent, Atrium; Fibrillation, Atrial Arrhythmia
- Trial name
- CLIP-AF (NCT06165510)
- Testing
- Epicardial AF ablation using AtriCure EPi-Sense-AF Guided Coagulation System with Left Atrial Appendage Exclusion using the AtriCure LARIAT Suture Delivery Device., Standard Endocardial Catheter Ablation
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation, Arrhythmias, Cardiac
Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion
This study is a prospective, multi-center, randomized controlled trial. The subjects are patients scheduled to undergo a combined procedure of atrial fibrillation (AF) ablation and left atrial appendage (LAA) occlusion.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT06455644
- Testing
- CT group, DSA group
- Where
- 5 sites in China
- Volunteers
- 238 people
- Sponsor
- First Affiliated Hospital of Shantou University Medical College
Atrial Fibrillation, Arrhythmia
The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation
To investigate whether statin therapy utilizing the drug Lipitor (atorvastatin) might be effective in preventing short-and long-term atrial fibrillation (AF) following a left atrial ablation procedure.
- Conditions
- Atrial Fibrillation, Arrhythmia, Inflammation, Endothelial Dysfunction
- Trial name
- ATTAC (NCT00579098)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation (AF), Ablation Techniques
Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation
This is a prospective, randomized clinical trial evaluating the efficacy and safety of two techniques for repeat catheter ablation in patients with recurrent atrial fibrillation (AF): thermal energy ablation (radiofrequency) and…
- Conditions
- Atrial Fibrillation (AF), Ablation Techniques, Radiofrequency Catheter Ablation, Pulsed Field Ablation
- Trial name
- ERA-rePVI (NCT07141745)
- Testing
- Pulsed field ablation of reccurent atrial arrythmia, Radiofrequency ablation of reccurent atrial arrythmia (standard of care)
- Where
- Poland
- Volunteers
- 250 people
- Sponsor
- Wroclaw Medical University
Atrial Fibrillation
Short Term Outcomes From Minimally Invasive Surgery for the Treatment of Atrial Fibrillation
The purpose of this study is to assess the efficacy of minimally invasive surgery for atrial fibrillation.
- Trial name
- NCT00571597
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Virginia Commonwealth University
Atrial Fibrillation, Left Atrial Appendage Closure
Registry on Luma Vision's VERAFEYE System (ENLIgHT)
The objective of the study is to compile real-world data on the use of the VERAFEYE System in standard of care atrial fibrillation (AF) ablation procedures and left atrial appendage closure (LAAC) procedures.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure, Atrial Arrhythmia
- Trial name
- ENLIgHT (NCT06293430)
- Testing
- VERAFEYE System
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Atrial Fibrillation, Catheter Ablation
Bladder Catheters During Ablation Procedures
Inserting a Bladder catheter during catheter ablation is standard practice at most Institutions. Unfortunately, bladder catheters are associated with adverse outcomes, including catheter associated cystitis, hematuria, dysuria…
- Conditions
- Atrial Fibrillation, Catheter Ablation, Catheter Complications
- Trial name
- NCT03635034
- Testing
- Insert bladder catheter, No catheter
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- St. Vincent Cardiovascular Research Institute
Atrial Fibrillation, Atrial Tachycardia
AutoMatic disPERsion Tagging Function Preliminary Evaluation
Interventional, prospective, non-randomized, single-center, non-controlled clinical investigation as part of the premarket clinical evaluation of VX1+ medical device, aiming to verify that VX1+ in bidirectional configuration with…
- Conditions
- Atrial Fibrillation, Atrial Tachycardia, Atrial Arrhythmia
- Trial name
- AMPERE (NCT05362656)
- Testing
- VX1+ dispersion mapping
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Volta Medical
Atrial Fibrillation
Hybrid Procedure in Patients With Persistent Atrial Fibrillation
In this study, the investigators therefore comparatively analyzed the mid-term results (at 1 year) including electrocardiogram, 24 hour Holter monitoring, and 2 week long-term electrocardiogram of thoracoscopic ablation and RFCA…
- Trial name
- NCT02392338
- Testing
- Hybrid procedure
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Atrial Fibrillation
Visualization and Structured Attention Behaviour for Pain and Anxiety Reduction During Ablation of Atrial Fibrillation
The purpose of this study is to test the efficacy of visualization and relaxation exercises together with a structured behavioural attention from nurses during ablation of atrial fibrillation.
- Trial name
- NCT01162811
- Testing
- visualization together with structured behavioural attention.
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cardiovascular Diseases, Arrhythmias, Cardiac
Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access Study
The ICE-ACCESS study is a prospective observational study designed to evaluate how procurement reliability, distribution restrictions, supply-chain interruptions, and device availability affect access to intracardiac…
- Conditions
- Cardiovascular Diseases, Arrhythmias, Cardiac, Atrial Fibrillation
- Trial name
- ICE-ACCESS (NCT07788040)
- Testing
- Intracardiac Echocardiography Catheter
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Atrial Fibrillation
Ablation STrategies for Repeat PrOcedures in Patients With Atrial Fibrillation Recurrences
The aim of the study is to evaluate different ablation strategies in patients with AF recurrences despite chronic PVI after prior catheter ablation.
- Trial name
- ASTRO AF (NCT04056390)
- Testing
- Catheter ablation using irrigated radiofrequency current ablation or cryothermal energy
- Where
- 7 sites in Germany
- Volunteers
- 256 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
Persistent Atrial Fibrillation
Repetitive Activation Patterns and Focal Impulses Identification and Ablation in Persistent AF
The primary purpose of this study is to assess the effectiveness of using CARTOFINDER™ maps created by the RHYTHMFINDER-192 catheter and the CARTOFINDER™ Algorithm to terminate persistent atrial fibrillation (PsAF) to either…
- Trial name
- RAPID-AF (NCT03064451)
- Testing
- cartofinder guided ablation followed by PVI
- Where
- 7 sites in Belgium, Canada and 2 more
- Volunteers
- 60 people
- Sponsor
- Biosense Webster, Inc.
Atrial Fibrillation
A Fib Clinic of the Future Using KardiaPro Platform for Chronic Care of Patients With AF After Ablation Procedure
Pulmonary vein isolation is a widely used strategy for the treatment of patients with symptomatic atrial fibrillation. After successful pulmonary vein isolation (no atrial fibrillation on transtelephonic rhythm recordings for 3…
- Trial name
- AliveCor (NCT03557034)
- Testing
- Kardia Monitoring
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Atrial Fibrillation
The Effect of an Intervention Based on The CSM on Self-Management in Patients After Atrial Fibrillation Ablation
Aim The investigators will validate the feasibility and effectiveness of a self-management intervention program based on the Common-Sense Model of Self-Regulation for patients after atrial fibrillation ablation.
- Trial name
- NCT07741682
- Testing
- Intervention of the CSM-Based Self-Management Protocol for Patients After Radio frequency Ablation for Atrial Fibrillation Intervention Group, Intervention of the CSM-Based Self-Management Protocol for Patients After Radio frequency Ablation for Atrial Fibrillation Control Group
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Binzhou People's Hospital
Hemostasis
Study of Hemostasis During the Atrial Fibrillation Ablation Procedure
Anticoagulation monitoring is done by monitoring the ACT (Activated Clotting Time) with an objective greater than 300 s. Until now, treatment with direct oral anticoagulant (for the prevention of thromboembolic events of atrial…
- Trial name
- EHPAFAVE (NCT05128110)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Longstanding Persistent Atrial Fibrillation
Evaluation of the Cardioblate CryoFlex Surgical Ablation System in Longstanding Persistent Atrial Fibrillation
Studies have shown that taking drugs to stay out of AF has limited success. This research is designed to study heart rhythm after surgical therapy, namely by measuring if there are benefits to having surgery to treat Atrial…
- Trial name
- CRYO-AF (NCT01558635)
- Testing
- Cardioblate CryoFlex Surgical Ablation, Mitral Valve surgery, Medtronic Reveal XT Insertable Cardiac Monitor
- Where
- 4 sites in Germany, Israel and 2 more
- Volunteers
- 17 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation
Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After Atrial Fibrillation Ablation Procedure
The investigators goal in this study is to examine the feasibility and efficacy of AliveCor iphone case monitoring device in monitoring patients after AF ablation by comparing transmissions using Alive Cor with transmissions from…
- Trial name
- iTransmit (NCT01912911)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Cleveland Clinic
Pulmonary Vein Isolation, Ablation Time, Procedure Time, Freedom Form Atrial Fibrillation
Pulmonary Vein Ablation of Atrial Fibrillation Using Magnetic Navigation: Single Ring Versus Circumferential Techniques
The single-ring ablation method aims for isolation of the posterior LA wall including the pulmonary veins. If avoiding ablation on the posterior LA wall esophageal injury is unlikely.
- Trial name
- NCT01583075
- Testing
- Circumferential pulmonary vein ablation, single ring pulmonary vein ablation
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Medical Center Goettingen
Atrial Fibrillation (AF), Obesity & Overweight
Waiting on Atrial Fibrillation Intervention Therapy (WAIT) Study
Atrial fibrillation (AF) is the most common heart rhythm disorder and is associated with symptoms, reduced quality of life, heart failure, stroke, and a high risk of recurrence after catheter ablation.
- Trial name
- WAIT (NCT07275697)
- Testing
- Semaglutide 2.4 mg, Standard medical treatment
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Emma Svennberg