Clinical trials: Atrial Fibrillation Ablation Procedure
Atrial Fibrillation, Arrhythmias, Cardiac
Accuracy of LAA Occluder Size Selection: CT vs. DSA During Combined AF Ablation and LAA Occlusion
This study is a prospective, multi-center, randomized controlled trial. The subjects are patients scheduled to undergo a combined procedure of atrial fibrillation (AF) ablation and left atrial appendage (LAA) occlusion.
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT06455644
- Testing
- CT group, DSA group
- Where
- 5 sites in China
- Volunteers
- 238 people
- Sponsor
- First Affiliated Hospital of Shantou University Medical College
Atrial Fibrillation, Persistent or Longstanding Persistent Atrial Fibrillation
Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach
The objective of this study is to establish the safety and effectiveness of a dual epicardial and endocardial ablation procedure for patients presenting with Persistent Atrial Fibrillation or Longstanding Persistent Atrial…
- Trial name
- DEEP (NCT02393885)
- Testing
- AtriCure Bipolar System and AtriClip® PRO LAA Exclusion System, Endocardial Ablation
- Where
- 17 sites in United States, Belgium and 1 more
- Volunteers
- 90 people
- Sponsor
- AtriCure, Inc.
Persistent Atrial Fibrillation
Effect of Empirical Left Atrial Appendage Isolation on Long-term Procedure Outcome in Patients With Persistent or Long-standing Persistent Atrial Fibrillation Undergoing Catheter Ablation
The purpose of this prospective randomized study is to assess whether empirical Left Atrial Appendage (LAA) isolation along with the standard approach of pulmonary vein isolation (PVI) and ablation of extra-pulmonary triggers is…
- Trial name
- BELIEF (NCT01362738)
- Testing
- RFCA of PV and extra-PV triggers, LAA isolation along with the conventional ablation strategy
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation
Safety and Efficacy Study of The Combined Ablation Procedure To Treat Longstanding Persistent Atrial Fibrillation
This is a multi-center, prospective open label, feasibility study evaluating the safety and efficacy of the combined ablation procedure for the treatment of longstanding persistent atrial fibrillation.
- Trial name
- CAPstopsLSPAF (NCT01103661)
- Testing
- Numeris®-AF Guided Coagulation System with VisiTrax®
- Where
- 4 sites in United States
- Volunteers
- 7 people
- Sponsor
- nContact Surgical Inc.
Atrial Fibrillation (AF), Atrial Flutter
Registry of Atrial Arrhythmia Ablation Procedures Using Pulsed Field Ablation in Poland
The aim of the described project is to establish a multicenter, nationwide registry of atrial arrhythmia ablation procedures using the Pulsed Field Ablation (PFA) method.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Atrial Tachycardia, Ablation Techniques
- Trial name
- PFA Registry (NCT07109141)
- Testing
- PFA ablation procedure of atrial arrythmia
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Wroclaw Medical University
Atrial Fibrillation
Assessment of Safety and Effectiveness in Treatment Management of Atrial Fibrillation With the BWI IRE Ablation System
To demonstrate the safety and 12-month effectiveness of the VARIPULSE™ Catheter when used in conjunction with the TRUPULSE™ Generator for pulmonary vein isolation (PVI) in the treatment of subjects with symptomatic paroxysmal…
- Trial name
- AdmIRE (NCT05293639)
- Testing
- Pulse Field Ablation
- Where
- 30 sites in United States
- Volunteers
- 362 people
- Sponsor
- Biosense Webster, Inc.
Persistent Atrial Fibrillation, Longstanding Persistent Atrial Fibrillation
Comparison of Treatment Outcomes Between Convergent Procedure and Catheter Ablation for Persistent and Longstanding Persistent Atrial Fibrillation
In the last 20 years, atrial fibrillation has become one of the leading healthcare burden in Europe and other developed countries.
- Trial name
- NCT04509180
- Testing
- Catheter ablation, Convergent procedure
- Where
- Slovenia
- Sponsor
- University Medical Centre Ljubljana
Atrial Fibrillation Ablation Procedure
Atrial Fibrillation Ablation on Gastric Motility "The AF Gut Study"
You are being scheduled to undergo an ablation procedure to treat your atrial fibrillation. Complications of ablation procedures include damage to structures near the heart from the heat energy used during the ablation procedure.
- Trial name
- NCT01396356
- Testing
- GI procedures
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dhanunjaya Lakkireddy, MD, FACC
Atrial Fibrillation, Arrhythmia
The Use of Statins Following a Left Atrial Catheter Ablation Procedure to Prevent Atrial Fibrillation
To investigate whether statin therapy utilizing the drug Lipitor (atorvastatin) might be effective in preventing short-and long-term atrial fibrillation (AF) following a left atrial ablation procedure.
- Conditions
- Atrial Fibrillation, Arrhythmia, Inflammation, Endothelial Dysfunction
- Trial name
- ATTAC (NCT00579098)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation, Left Atrial Appendage Closure
Registry on Luma Vision's VERAFEYE System (ENLIgHT)
The objective of the study is to compile real-world data on the use of the VERAFEYE System in standard of care atrial fibrillation (AF) ablation procedures and left atrial appendage closure (LAAC) procedures.
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Closure, Atrial Arrhythmia
- Trial name
- ENLIgHT (NCT06293430)
- Testing
- VERAFEYE System
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Single Ablation Procedure Using a PVI-Only Strategy
The aim is to use the Advisor™ HD Grid Mapping Catheter, Sensor Enabled™ to characterize the atrial substrate and develop a model for predicting recurrence rates after a single procedure using a PVI only approach and a contact…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Cardiac Arrhythmia
- Trial name
- WAVE-MAP AF (NCT03882021)
- Testing
- A specific electrophysiology mapping protocol is applicable with the GRID catheter.
- Where
- 15 sites in Austria, Czechia and 7 more
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Atrial Fibrillation, Restore of Sinus Rhythm
AMAZING PRAGUE (PRAGUE-12)
Aim of the project is to assess the long-time clinical impact of surgical ablation (MAZE procedure) on patients who suffer from atrial fibrillation but are indicated to a cardiac surgery for other predominant cardiac diagnosis…
- Conditions
- Atrial Fibrillation, Restore of Sinus Rhythm, Post-Operative Complications
- Trial name
- AmP (NCT00665587)
- Testing
- Cox-MAZE III
- Where
- 3 sites in Czechia
- Volunteers
- 220 people
- Sponsor
- Charles University, Czech Republic
Atrial Fibrillation, Atrial Flutter
Feasibility Study on the VERAFEYE Imaging and Navigation System for Guided Catheter Ablation Procedures
The objective of the study is to collect data on the usability and integration of the VERAFEYE Imaging and Guidance System in adult patients indicated to undergo a standard of care catheter-based ablation procedure for the…
- Conditions
- Atrial Fibrillation, Atrial Flutter, Atrial Arrhythmia
- Trial name
- INSiGHT (NCT07271238)
- Testing
- VERAFEYE Imaging and Guidance System
- Where
- Croatia
- Volunteers
- 50 people
- Sponsor
- LUMA Vision Ltd.
Atrial Fibrillation (AF), Cardiomyopathy, Secondary
Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial Fibrillation
Atrioventricular node ablation with permanent pacing (the "pace-and-ablate" strategy) controls ventricular rate in atrial fibrillation that has not responded to drug therapy or catheter ablation.
- Conditions
- Atrial Fibrillation (AF), Cardiomyopathy, Secondary, Pacing-Induced Cardiomyopathy, Heart Failure
- Trial name
- REPACE (NCT07852221)
- Where
- 5 sites in Poland, Switzerland and 1 more
- Volunteers
- 2,600 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Atrial Fibrillation
A Prospective Multi Centre Trial on Bipolar Radiofrequency Ablation of Atrial Fibrillation
The study is a prospective multi-centre study to investigate the effect of a new bipolar ablation strategy of the left atrium in patients with paroxysmal or permanent atrial fibrillation over time.
- Trial name
- NCT00184249
- Testing
- Bipolar radiofrequency ablation
- Sponsor
- Norwegian University of Science and Technology
Atrial Fibrillation
Hidden Slow Conduction Ablation for Recurrent Atrial Fibrillation: Unmasking the Arrhythmogenic Substrate (Unmask-AF)
Over recent years, pulmonary vein isolation (PVI) procedures have demonstrated progressively enhanced efficacy and safety, resulting in a substantial increase in the number of atrial fibrillation ablations, not only as a…
- Trial name
- NCT06657170
- Testing
- Pulmunary veins reconnection plus hidden slow conduction ablation, Pulmunary veins (PV) reconnection ablation only
- Volunteers
- 212 people
- Sponsor
- Centro Medico Teknon
Paroxysmal Atrial Fibrillation
Safety and Efficacy Study of the Combined Ablation Procedure to Treat Paroxysmal Atrial Fibrillation
This is a multi-center, prospective, open label, feasibility clinical study,evaluating the safety and efficacy of the combined ablation procedure for the treatment of symptomatic paroxysmal atrial fibrillation.
- Trial name
- CAP STOPS AF (NCT01103674)
- Testing
- Numeris®-AF Guided Coagulation System with VisiTrax®
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- nContact Surgical Inc.
Cardiovascular Diseases, Arrhythmias, Cardiac
Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access Study
The ICE-ACCESS study is a prospective observational study designed to evaluate how procurement reliability, distribution restrictions, supply-chain interruptions, and device availability affect access to intracardiac…
- Conditions
- Cardiovascular Diseases, Arrhythmias, Cardiac, Atrial Fibrillation
- Trial name
- ICE-ACCESS (NCT07788040)
- Testing
- Intracardiac Echocardiography Catheter
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Atrial Fibrillation, Catheter Ablation
Electroacupuncture Intervention in Catheter Ablation of Atrial Fibrillation
This is a randomized control trial to determine whether electroacupuncture(EA) intervention with Morphine can reduce the intraoperative pain and early post-operative complications in patients undergoing catheter ablation of…
- Trial name
- NCT05575544
- Testing
- Acupuncture plus morphine
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Atrial Fibrillation
Prophylactic Pulmonary Vein Isolation Study
This study is being done to learn the effects of the Pulmonary Vein Isolation in patients that are at high risk to developing, but do not have a documented history of atrial fibrillation.
- Trial name
- NCT00587899
- Testing
- Pulmonary Vein Isolation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic