Clinical trials: Atresia
Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia
Palliative Care Needs of Children With Rare Diseases and Their Families
The palliative care needs of family caregivers of children with rare diseases and their children are largely unmet, including the need for support to prepare for future medical decision making.
- Conditions
- Trisomy 13 Syndrome, Arthrogryposis Congenita Multiplex With Intestinal Atresia, Asparagine Synthetase Deficiency, CHARGE Syndrome
- Trial name
- FACE-Rare (NCT06938542)
- Testing
- Family Centered pediatric palliative care for family caregivers of children with rare diseases.
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Children's National Research Institute
Water-Electrolyte Imbalance, Intensive Care Units
Fluid Overload and Pulmonary Function
Esophageal atresia is a rare but severe malformation, and it requires early surgery. Coloesophagoplasty is surgical repair of the esophageal with an isoperistaltic transverse colon graft.
- Conditions
- Water-Electrolyte Imbalance, Intensive Care Units, Pediatric, Critical Illness
- Trial name
- NCT05129930
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Pirogov Russian National Research Medical University
Esophageal Atresia
Endoscopic Ultrasound Findings in Esophageal Atresia Following Surgical Repair
Children with esophageal atresia who undergo surgical repair are at risk for anastomotic stricture following surgery. Esophageal stricture can be treated with serial endoscopic dilation but may ultimately need surgical resection…
- Trial name
- NCT04259528
- Testing
- Pediatric endoscopic ultrasound
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Hearing Loss, Conductive Hearing Loss
Evaluation of the Ponto Bone Anchored Hearing System in a Pediatric Atresia Population
The purpose of this study is to in a proactive manner collect high quality data from a pediatric patients who have undergone a bone anchored hearing solution, using the Ponto BHX implant, in clinical practice.
- Conditions
- Hearing Loss, Conductive Hearing Loss, Atresia
- Trial name
- NCT03723161
- Testing
- Bone Achored Hearing surgery
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Oticon Medical
Esophageal Atresia, Enhanced Recovery After Surgery
Application of Enhanced Recovery After Surgery for Congenital Esophageal Atresia During Perioperative Period
The purpose of this prospective cohort study is to evaluate the safety and effectiveness of enhanced recovery after surgery (ERAS) to perform routine thoracoscopic repair for elective esophageal atresia type C
- Trial name
- ERASforCEA (NCT04072419)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Dysphagia, Quality of Life
Caregivers of Children With Repaired Esophageal Atresia-tracheoesophageal Fistula
Children with esophageal atresia and tracheoesophageal fistula (EA-TEF) may experience feeding and swallowing difficulties, which result in stressful interactions between children and caregivers, and potentially impact the…
- Trial name
- NCT03889041
- Testing
- Quality of life assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Choanal Atresia
Use of Mometasone Eluting Stent in Choanal Atresia
This study is to find out how well drug-eluting stents work as part of treatment for choanal atresia repair. Participants will be receiving surgical choanal atresia repair; half will get a drug-eluting stent placed, the other…
- Trial name
- NCT03605537
- Testing
- Drug-eluting Stent Mometasone
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pulmonary Artery Stenosis, Tetralogy of Fallot
Retrospective Review of Anesthetic Considerations for Pulmonary Artery Rehabilitation
Pulmonary artery rehabilitation procedure is done frequently in the catheterization suite for patients with pulmonary artery stenosis or small pulmonary arteries following surgical repair for patients with tetralogy of Fallot…
- Conditions
- Pulmonary Artery Stenosis, Tetralogy of Fallot, Pulmonary Atresia
- Trial name
- NCT02586740
- Testing
- Pulmonary artery rehabilitation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Aymen N Naguib
Biliary Atresia
Survival With Own Liver of Conventional Versus Laparoscopic Kasai for Biliary Atresia
This study evaluated laparoscopic (videosurgery) versus conventional (open surgery) Kasai portoenterostomy (anastomosis of small intestine to the liver hilus) in children with biliary atresia.
- Trial name
- NCT01063699
- Testing
- Laparoscopic Kasai operation
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- Hannover Medical School
Chewing Problem
Chewing in Children With Repaired Esophageal Atresia-tracheoesophageal Fistula
The investigators aim to evaluate chewing function in children with repaired esophageal atresia-tracheoesophageal fistula (EA-TEF). Patients with repaired EA-TEF will be evaluated for age, sex, type of atresia.
- Trial name
- NCT03026491
- Testing
- Chewing evaluation
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Tracheoesophageal Fistula, Esophageal Atresia
Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients
The investigators propose a preliminary study performing exome sequencing on samples from patients and their biologically related family members with tracheal and esophageal birth defects (TED).
- Conditions
- Tracheoesophageal Fistula, Esophageal Atresia, Laryngeal Cleft, Tracheal Stenosis
- Trial name
- TED (NCT03455881)
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
NEC, Gastroschisis
Neokare Safety and Tolerability Assessment in Neonates With GI Problems
With an increasing body of evidence to support a causal link between drinking milk that contain cow's milk protein (CMP) and the development of gastrointestinal disturbance in infants, many clinicians avoid the use of CMP…
- Conditions
- NEC, Gastroschisis, Intestinal Perforation, Atresia, Intestinal
- Trial name
- NCT05293353
- Testing
- NeoKare Breast Milk Fortifier
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Anesthesia, Pediatrics
Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy
This study aims to assess the efficacy and safety of prophylactic intraoperative norepinephrine infusion versus the standard technique on decreasing the incidence of intraoperative hypotension in infants undergoing Kasai…
- Conditions
- Anesthesia, Pediatrics, Biliary Atresia
- Trial name
- NCT05521152
- Testing
- Norepinephrine Bitartrate
- Where
- Egypt
- Volunteers
- 31 people
- Sponsor
- Kasr El Aini Hospital
Esophageal Atresia, Anastomotic Stenosis
Oral Viscous Budesonide in Anastomotic Stricture After Esophageal Atresia Repair (OVB in EA)
The aim of this study is to perform a multicentre, prospective, randomized, placebo controlled, double-blinded study to demonstrate the potential and beneficial effects of OVB in the prevention of recurrence of anastomotic…
- Trial name
- OVB in EA (NCT03999008)
- Testing
- Budesonide Oral
- Volunteers
- 60 people
- Sponsor
- St. Justine's Hospital
Esophageal Atresia
National Register of Oesophageal Atresia
The esophageal atresia is a group of birth defects including a break in continuity of the esophagus with or without persistent communication with the trachea (tracheoesophageal fistula), sometimes associated (from 50%) of other…
- Trial name
- REGATE (NCT02883725)
- Testing
- data collection
- Where
- 37 sites in France, Guadeloupe and 1 more
- Volunteers
- 1,460 people
- Sponsor
- University Hospital, Lille
to Find Out Non-invasive Indices to Predict the Status of Hepatic Fibrosis in BA Patients.
the Correlation Between Non-invasive Indicators in Patients With Biliary Atresia
we propose this study and try to find out possible clinical applicable non-invasive imaging indices or its combination with the laboratory indices to predict the status of hepatic fibrosis in BA patients.
- Trial name
- NCT02848573
- Volunteers
- 41 people
- Sponsor
- National Taiwan University Hospital
Biliary Atresia
Biliary Atresia, Hepatic Buffer Response and Sevoflurane
To evaluate the effects of sevoflurane on hepatic blood flow (HBF) and hepatic arterial buffer response (HABR) in infants with obstructive jaundice by Doppler ultrasound.Twenty-five infants with biliary atresia (1-3…
- Trial name
- NCT02471209
- Testing
- Sevoflurane
- Volunteers
- 25 people
- Sponsor
- Children's Hospital of Fudan University
Esophageal Atresia
High-resolution Esophageal Manometry
EA is one of the most frequent birth defects, with an incidence of 1 in 3000 live births1. Until the 1950s, these patients had 100% mortality; nowadays, the survival rate is greater than 90%, and only those with associated severe…
- Trial name
- NCT03415893
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Hospital El Cruce
Liver Cirrhosis, Biliary
Autologous Bone Marrow Mononuclear Stem Cell for Children Suffering From Liver Cirrhosis Due to Biliary Atresia
The aim of this study was to evaluate the safety and effectiveness of autologous bone marrow mononuclear stem cell transplantation for Children Suffering from Liver Cirrhosis Due to Biliary Atresia
- Trial name
- NCT03468699
- Testing
- Autologous BMMC transplantation
- Where
- 2 sites in Vietnam
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Esophageal Atresia
Individualized Management for Long Gap Esophageal Atresia
The treatment of long gap esophageal atresia (LGEA) in neonates is one of the most challenging congenital malformations in neonatal surgery.
- Trial name
- NCT03023865
- Testing
- Staged stress function
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine