Clinical trials: Asymptomatic Infections
Urinary Tract Infection, Asymptomatic Bacteriuria
Efficacy of Fosfomycin-Trometamol in Urinary Tract Infection Prophylaxis After Kidney Transplantation
Urinary tract infections (UTI) are the most common complications after kidney transplantation. Most series have reported incidence between 20 to 50% during the first year.
- Conditions
- Urinary Tract Infection, Asymptomatic Bacteriuria, Allograft Rejection, Microbiologic Resistance
- Trial name
- NCT01820897
- Testing
- Fosfomycin-Trometamol, Sulfamethoxazole trimethoprim
- Where
- 2 sites in Mexico
- Volunteers
- 130 people
- Sponsor
- JOSE MANUEL ARREOLA GUERRA
Asymptomatic HIV, HIV Infections
ID and Testing Via Friendship Networks
This is a pilot study with a cross-sectional research design to recruit Hispanic/Latina and African American adolescent and young adult women, aged 13-24 years to serve as index recruiters, who will in turn recruit members of her…
- Trial name
- NCT00841360
- Testing
- Index Recruiter, Friendship Network Member
- Where
- 3 sites in United States
- Volunteers
- 535 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Asymptomatic P.Falciparum Malaria
Artemisia Annua Infusion for the Treatment of Asymptomatic Plasmodium Falciparum Infection
The goal of this clinical trial is to determine whether Artemisia annua dried leaves, used as an infusion, can treat individuals with malaria parasites but no symptoms.
- Trial name
- ART-CT001 (NCT07819825)
- Testing
- Artemisia Annua Leaf, Centaurii herba
- Where
- Gabon
- Volunteers
- 20 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
SARS-CoV2 Infection
A Trial of Novaferon in Asymptomatic or Mild COVID-19 Patients
This is a phase III randomized, double blinded, placebo-controlled multi-center study to assess the efficacy and safety of aerosolized Novaferon for the treatment of asymptomatic or mildly patients infected with SARS-CoV-2.
- Trial name
- NCT05017714
- Testing
- Recombinant cytokine gene derived protein injection
- Volunteers
- 300 people
- Sponsor
- Beijing 302 Hospital
Colonization, Asymptomatic, Colonization
Probiotic Delivered to the Small Intestine Changes Microbiota
This study will determine whether encapsulation of probiotic bacteria using natural plant protein can enhance bacterial colonisation.
- Trial name
- Probiotic (NCT07510282)
- Testing
- Probiotic containing L.rhamnosus R0011 strain, 200 ml yogurt drink
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University College Dublin
SARS CoV 2 Infection
Rutgers Pilot for PREDICT- Patient POC Test
A pilot study was initiated to assess feasibility of testing asymptomatic dental patients presenting to the Oral Medicine Clinic at Rutgers School of Dental Medicine for SARS-CoV-2 viral antigen using a point-of-care (POC) Rapid…
- Trial name
- NCT05612724
- Testing
- Testing for SARS CoV2 Antigen
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tuberculosis
A Step Forward for Unraveling the Immune Mechanisms and Tools for Tuberculosis Spectrum Management
Tuberculosis (TB) is a significant infectious disease worldwide, with millions of people infected and major impact on mortality and public health.
- Trial name
- TB-SPECTRUM (NCT07735754)
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- Irene Latorre Rueda
COVID-19
Wearable Diagnostic for Detection of COVID-19 Infection
The goals of this study are 1) to validate the use of a wearable diagnostic capability and software as a medical device (SaMD) algorithm for the pre or early-symptomatic detection of COVID-19 infection, 2) assess the wearable…
- Trial name
- NCT04742569
- Where
- United States
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- ClinOne, Inc.
HIV Infections
A Randomized, Dose-ranging Study of Alferon LDO in Asymptomatic HIV+ Subjects
To conduct a randomized dose-ranging study to evaluate the safety and activity of orally administered low dose interferon alfa-n3 as an immunomodulator in subjects with asymptomatic HIV-1 infection.
- Trial name
- NCT00215852
- Testing
- Alferon LDO
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- AIM ImmunoTech Inc.
Immunologic Activity Alteration
Asymptomatic COVID-19 Infection Among Healthcare Workers
To assess the seroprevalence of SARS-CoV-2 IgG in Health care workers in three University Hospitals
- Trial name
- NCT04354792
- Testing
- Serum SARs COV 2 IGg screening in health care workers
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Asymptomatic Bacteriuria, Bacteriuria
The Bacteriuria in Renal Transplantation (BiRT) Study: A Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria
The purpose of this study is to compare antibiotics versus no-treatment in kidney transplant recipients with asymptomatic bacteriuria.
- Conditions
- Asymptomatic Bacteriuria, Bacteriuria, Urinary Tract Infections, Kidney Transplantation
- Trial name
- BiRT (NCT01871753)
- Testing
- Anti-Infective Agents
- Where
- 15 sites in Belgium, France
- Volunteers
- 198 people
- Sponsor
- Erasme University Hospital
Covid19
Face Masks to Reduce SARS-CoV-2 Infections (COVID-19) in Bangladesh
The primary goal of the village-level intervention is to assess whether mask-wearing reduces community-level asymptomatic and symptomatic SARS-CoV-2 infections, assessed via PCR testing.
- Trial name
- NCT05197725
- Testing
- Face mask, Face mask awareness, Face mask promotion through community values or individual information
- Where
- Bangladesh
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Vaginosis, Bacterial, Infertility
Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population
Bacterial vaginosis (BV) is a common vaginal infection characterized by a pathologic shift in the normal vaginal flora. BV has been associated with a number of poor reproductive outcomes, including infertility, preterm labor and…
- Conditions
- Vaginosis, Bacterial, Infertility, Miscarriage
- Trial name
- NCT01322971
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Stanford University
Surgery, COVID
Surgery During Covid-19: The Role of Asymptomatic Patients, a Survey
a brief questionnaire to get a clearer picture of the situation regarding surgical patients with special emphasis on asymptomatic Covid-19 patients.
- Conditions
- Surgery, COVID, Asymptomatic Patient, Covid-19
- Trial name
- NCT04344197
- Testing
- global survey
- Where
- Italy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Rome Tor Vergata
SARS-CoV-2, COVID-19
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Buccal Screening Evaluation Using an RT-PCR Assay and a Rapid ELISA Test Among Symptomatic and Asymptomatic Patients
The main objective is to expand screening for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by evaluating the diagnostic accuracy of the RT-PCR test (Cobas® Roche, Switzerland) and the ELISA Point of Contact…
- Trial name
- CORDAGES (NCT05074745)
- Testing
- ELISA POCT vs RT-PCR
- Where
- Monaco
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Centre Scientifique de Monaco
HIV Infections
The Effectiveness of Indinavir Plus Zidovudine Plus Lamivudine in HIV-Infected Patients With No Symptoms of Infection
To evaluate the ability of the combination of indinavir, zidovudine, and lamivudine to suppress HIV-1 infection as measured by: (1) the maintenance of HIV-1 serum viral RNA below the limit of detection of the most sensitive…
- Trial name
- NCT00002179
- Testing
- Indinavir sulfate, Lamivudine, Zidovudine
- Where
- 17 sites in United States, Canada
- Volunteers
- 200 people
- Sponsor
- Merck Sharp & Dohme LLC
Malaria, Malaria, Asymptomatic Parasitaemia
Impact of Scaling up Mass Testing, Treatment and Tracking on Malaria Prevalence Among Children
Malaria poses a serious burden in sub-Sahara Africa. Efforts are ongoing to scale up interventions that work. These include the use of Long Lasting Insecticidal Nets (LLIN), Intermittent Preventive Treatment in children (IPTc)…
- Trial name
- NCT04167566
- Testing
- Artemisinin Combination Therapy ACTs
- Where
- Ghana
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Malaria
Evaluating the Role of Chloroquine for Malaria Elimination
One of the proposed ideas for malaria elimination includes the use of drugs to interrupt malaria transmission by exhausting the human reservoir of infection.
- Trial name
- Cloroquina (NCT02698748)
- Testing
- Chloroquine
- Where
- Mozambique
- Volunteers
- 75 people
- Sponsor
- Centro de Investigacao em Saude de Manhica
HIV Infections
Assessment of Asymptomatic Heart Disease in Children With HIV
The purpose of this study is to perform cardiac evaluation in HIV-1 (predominantly clade C)infected children by history, physical examination, echocardiogram and plasma N-terminal pro-B-type natriuretic peptide (N-BNP)measurement…
- Trial name
- NCT00426374
- Testing
- echocardiography and blood test
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Severe Acute Respiratory Syndrome
Study of Alferon® LDO (Low Dose Oral) in Normal Volunteers
The purpose of this trial is to conduct a randomized dose-ranging study to evaluate the safety and activity of orally administered low dose interferon alfa-n3 as an antiviral and immunomodulator in asymptomatic subjects with…
- Trial name
- NCT00215826
- Testing
- Alferon LDO
- Where
- Hong Kong
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AIM ImmunoTech Inc.