Clinical trials: Asymptomatic Apical Periodontitis, active
Asymptomatic Apical Periodontitis
Effects of Intracanal Cryotherapy on Biomarkers and Postoperative Pain in Apical Periodontitis
This randomized controlled clinical study will evaluate the effects of intracanal cryotherapy during root canal treatment in patients with asymptomatic apical periodontitis.
- Trial name
- NCT07850219
- Testing
- Temperature-Controlled Intracanal Irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Medipol University
Post Endodontic Pain, Periapical Healing
Comparative Evaluation of Endodontic Instrumentation Kinematics and Cryotherapy on Post-endodontic Pain and Periapical Healing
TITLE : Comparative evaluation of two different endodontic instrumentation kinematics and cryotherapy on post endodontic pain and periapical healing in teeth with asymptomatic apical periodontitis - A double blind, prospective…
- Trial name
- NCT07500870
- Testing
- rotary instrumentation kinematics, reciprocating instrumentation kinematics
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Necrotic Pulp, Asymptomatic Apical Periodontitis
Evaluation of Postoperative Pain and Success Rate Between Lateral Condensation and Warm Vertical Obturation Techniques
Brief Summary Postoperative pain is a common complication following root canal treatment, particularly in necrotic teeth with asymptomatic apical periodontitis.
- Trial name
- NCT07310212
- Testing
- Warm Vertical Condensation (WVO), Cold Lateral Condensation (CLC)
- Where
- Jordan
- Volunteers
- 80 people
- Sponsor
- University of Jordan
Single-visit, Periapical Periodontitis
Postoperative Pain and Success of Single-Visit Root Canal Treatment Using Different Root Canal Sealers in Asymptomatic Teeth
This study evaluates the postoperative pain and long-term clinical and radiographic success of single-visit primary root canal treatment in asymptomatic teeth with periapical lesions.
- Trial name
- NCT07868315
- Testing
- One-Fill, TotalFill, AH Plus + Single Cone
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul Medipol University Hospital
Asymptomatic Apical Periodontitis, Root Canal Retreatment
Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer
The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in…
- Trial name
- NCT06973135
- Testing
- Bioceramic sealer root canal obturation, resin sealer root canal obturation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Saly Nazeer
Apical Periodontitis, Oxidative Stress
Effect of Ozone Use in Intracanal Irrigation on Oxidative Stress Level in Teeth With Asymptomatic Apical Periodontitis
This clinical study aims to investigate the oxidative stress-related effects of ozone irrigation in patients with asymptomatic apical periodontitis undergoing root canal treatment.
- Trial name
- NCT07171762
- Testing
- Ozonytron XP, Physiological saline solution (0.9% NaCl)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- KEZBAN MELTEM ÇOLAK
Asymptomatic Apical Periodontitis, Endodontic Retreatment
Cryotherapy, PGE2, NGF Levels and Pain After Endodontic Retreatment
This prospective, randomized, controlled, single-blind, parallel-group clinical trial evaluates whether intracanal cryotherapy reduces postoperative pain and inflammatory biomarker levels following single-visit endodontic…
- Conditions
- Asymptomatic Apical Periodontitis, Endodontic Retreatment, Cryotherapy
- Trial name
- ICE-PAIN (NCT07733700)
- Testing
- Intracanal cryotherapy, Room-temperature saline irrigation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Alanya Alaaddin Keykubat University
Retreatment, Asymptomatic Apical Periodontitis
Effects of Irrigation Activation Systems on Postoperative Pain and Lesion Healing in Single-Visit Retreatment
In this superiority randomized clinical trial with a parallel design, 75 asymptomatic maxillary anterior teeth with 2-5 mm periapical lesions and a history of primary root canal treatment (PRCT) at least four years earlier were…
- Trial name
- NCT07150585
- Testing
- Ultrasonic Activation Group, Sonic Activation Group, Laser Activation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ege University
Pulp and Periapical Tissue Disease
Gingival Crevicular Fluid Biomarkers and Healing After Root Canal Treatment in Asymptomatic Apical Periodontitis
This prospective observational cohort study will evaluate whether changes in gingival crevicular fluid osteoprotegerin (OPG) , RANKL/OPG ratio ,IL10,IL8and CxCL10 after primary nonsurgical root canal treatment are associated with…
- Trial name
- NCT07468643
- Testing
- Primary Nonsurgical Root Canal Treatment
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Asymptomatic Apical Periodontitis
Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment
This study aims to compare the effect of bio ceramic sealer and resin-based sealer on the intensity and occurrence of post operative pain in single rooted teeth with asymptomatic apical periodontitis.
- Trial name
- NCT06543004
- Testing
- AH plus sealer, Bioceramic sealer
- Where
- Qatar
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Primary Health Care Corporation, Qatar
Asymptomatic Apical Periodontitis
Sonic Irrigation Activation for Postoperative Pain After Root Canal Treatment
This randomized controlled clinical trial will evaluate whether sonic activation of the root canal irrigant using the EndoActivator system reduces postoperative pain after root canal treatment compared with conventional syringe…
- Trial name
- VAS (NCT07847333)
- Testing
- Sonic Irrigation Activation Using EndoActivator, Conventional Syringe Irrigation
- Volunteers
- 176 people
- Sponsor
- Saidu College of Dentistry
Asymptomatic Apical Periodontitis
Antimicrobial Effect of Calcium Silicate and Pectin as Intracanal Medications in Necrotic Teeth With Periapical Lesions
It is tackling antimicrobial resistance in endodontics, specifically comparing different intracanal medications used in root canal treatment.
- Trial name
- NCT07423663
- Testing
- Calcium Hydroxide Intracanal medication, Calcium silicate based intracanal medication, Pectin
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Asymptomatic Apical Periodontitis
Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain
This study aims to compare the effect of calcium-based bioceramic sealer and resin-based sealer on postoperative pain in adult patients with asymptomatic apical periodontitis undergoing root canal treatment.
- Trial name
- NCT07256691
- Testing
- Resin-based sealer obturation technique, Bioceramic sealer obturation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Fatima Memorial Hospital