Clinical trials: Asthma in Children
Molar Incisor Hypomineralization, Asthma in Children
Prevalence of Molar Incisor Hypomineralization Among Children Treated With Asthmatic Drugs Early in Their Lives
The aim of this study is to assess the prevalence of molar incisor hypo mineralization among children who have been treated with asthmatic drugs during the first three years of life.
- Trial name
- NCT04103710
- Where
- Egypt
- Volunteers
- 167 people
- Sponsor
- Cairo University
Asthma in Children, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05689983
- Testing
- Maintenance ICS and Symptom Driven SABA, Symptom-driven budesonide/formoterol combination
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Depressive Disorder, Major, Asthma
Impact of Caregiver Depression on Asthma in the Child
This study will examine if depression in a primary caregiver is associated with more hospitalization or ER visits in children with asthma.
- Trial name
- NCT00223288
- Testing
- Lexapro
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Texas Southwestern Medical Center
Asthma
Comparison of Breath-Enhanced and T-Piece Nebulizers in Children With Acute Asthma
This is a blinded observer randomized controlled trial comparing two nebulizer devices. The objective of this study is to evaluate the efficacy of two different nebulizers.
- Trial name
- NCT02566902
- Testing
- T-Piece Nebulizer, Breath-Enhanced Nebulizer, Albuterol
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Seton Healthcare Family
Asthma in Children, Atopy
Omalizumab Before Onset of Exacerbations
OBOE is a prospective, pilot, parallel group RCT with the overall aim of examining the effect of a single dose of anti-IgE (omalizumab) vs.
- Conditions
- Asthma in Children, Atopy, Viral Upper Respiratory Infection
- Trial name
- OBOE (NCT05332067)
- Testing
- Omalizumab
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Children's National Research Institute
Asthma
Maternal Variables Associated With Adherence in Children With Asthma
A questionnaire will be used in order to find out the reasons for poor adherence for long-term treatment in children with asthma.
- Trial name
- asthma (NCT00688792)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Asthma Acute
Analysis of Non-invasive Ventilatory Support Modes: High Flow Nasal Cannula and Non-invasive Ventilation
This study compares two types of noninvasive treatments for asthma attacks with the objective of analyzing the efficacy of each therapy during the period of exacerbations in infants and asthmatics hospitalized.
- Trial name
- NCT04033666
- Testing
- High Flow Nasal cannula, NIV Noninvasive Ventilation
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Nove de Julho
Dysfunctional Breathing, Asthma in Children
The Prevalence of Dysfunctional Breathing in Children and Adolescents With Asthma
The purpose of the study is to investigate the prevalence of dysfunctional breathing in children and adolescents with asthma in a hospital outpatient clinic.
- Conditions
- Dysfunctional Breathing, Asthma in Children, Asthma
- Trial name
- NCT04734795
- Where
- Denmark
- Volunteers
- 363 people
- Sponsor
- Kolding Sygehus
Asthma in Children
Analysis of Bronchial Remodeling Using Resonance Magnetic Imaging in Severe Asthmatic childrEn
This study is a diagnostic imaging pilot study evaluating performance of 3D-Ultrashort Time Echo (3D-UTE) Magnetic Resonance Imaging (MRI) for the diagnosis of bronchial remodeling in children with severe asthma.
- Trial name
- ARISE (NCT05419622)
- Testing
- bronchial biopsies
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Asthma in Children, Atrial Fibrillation
Mitigating the Health Effects of Desert Dust Storms Using Exposure-Reduction Approaches
The MEDEA project is envisioned to provide the field-based evidence for the adoption of a strategic plan for mitigating the health effects of desert dust storm (DDS) events in South-Eastern Europe.
- Trial name
- MEDEA (NCT03503812)
- Testing
- Intervention (1) for outdoor exposure reduction - Asthma in Children, Intervention (2) for outdoor and indoor exposure reduction - Asthma in Children, Intervention (1) for outdoor exposure reduction - Atrial Fibrillation
- Where
- 3 sites in Cyprus, Greece and 1 more
- Volunteers
- 310 people
- Sponsor
- University of Cyprus
Sickle Cell Disease
Propanolol and Red Cell Adhesion Non-asthmatic Children Sickle Cell Disease
Propanolol is a beta blocker which has been found to inhibit the ability of epinephrine to upregulate sickle red cell adhesion to laminin and endothelial cells in vitro.
- Trial name
- NCT02012777
- Testing
- propranolol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Miami
Controlled Asthma
Modelling of the Upper Airway in Children With Controlled Asthma
Asthma in children is recognized as a disease area with a high medical need. As the investigators move into this field it is necessary to improve the investigators knowledge of upper airway anatomical structure in paediatric…
- Trial name
- NCT01594151
- Testing
- Cone Beam Computed Tomography
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- FLUIDDA nv
Food Allergy Suspected, Food Allergy Proved
Association Between Asthma and Food Allergy
Prevalences of food allergies and asthma increased in the population during the last decades. These two pathologies, responsible for a real burden, are often associated and are to be considered as comorbidities; this aspect is…
- Trial name
- AAAli (NCT02884583)
- Testing
- Pulmonary function test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Asthma, Cystic Fibrosis
Breath Analysis in Children by New Point-of-care Instruments
In this study new hand-held devices for measuring exhaled breath will be tested in children with asthma, CF, and healthy controls. Main objectives will be feasibility and discriminative value of these techniques.
- Trial name
- NCT03377686
- Testing
- inflammation markers in exhaled breath
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Asthma
Multicentre Post-market Study of Ectoin® Inhalation Solution in Treatment of Asthma.
The goal of this multi-centre, prospective, open-label, single-arm, post-market clinical follow-up study is to further strengthen the already existing clinical evidence for supportive treatment and symptoms alleviation in asthma…
- Trial name
- EIL-AST (NCT05699941)
- Testing
- Ectoin® Inhalation Solution
- Where
- 5 sites in Poland
- Volunteers
- 204 people
- Sponsor
- Bitop AG
Asthma Bronchiale
Animated Video and Booklet Education for Improving Asthma Control and Medication Compliance in Children
Asthma is a chronic inflammatory disease that causes wheezing, coughing, and shortness of breath, and it is a significant cause of morbidity and mortality in the pediatric population.
- Trial name
- NCT06909318
- Testing
- Asthma Education - Animated Video, Booklet Group
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Trakya University
Bronchial Asthma
Behavioral Changes Among Asthmatic Children in Sohag Universty Hospital
Asthma is considered the most common chronic childhood disease and mainly affects children resident in urban areas. Asthma has been designated a serious public health problem due to the increase in its prevalence over the last…
- Trial name
- NCT06624735
- Testing
- psychometry
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Medication Adherence, Asthma in Children
The Tailored Adherence Incentives for Childhood Asthma Medications (TAICAM) Trial
Improving adherence to inhaled corticosteroids (ICS) medication in urban minority pediatric populations is a clinical and population health priority.
- Trial name
- NCT03907410
- Testing
- Nominal Financial Incentives, Daily Adherence Reminders/Adherence Performance Feedback
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Asthma, Smoking Cessation
Sustaining Smoking Cessation in Smokers With Kids With Asthma
Parents of Asthmatics Quit Smoking (PAQS-2) is a randomized controlled trial of a smoking cessation intervention for parents who smoke.
- Trial name
- PAQS2 (NCT00862368)
- Testing
- PAM, PAM-Enhanced/Asthma Counseling Phone Calls, Follow-Up Phone Calls - Child Wellness Topic
- Where
- 5 sites in United States
- Volunteers
- 573 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Asthma
Pediatric Asthma Alert Intervention for Minority Children With Asthma
Young inner-city children with asthma have the highest emergency department (ED) visit rates. Relying on the emergency department for asthma care can be a dangerous sign of poorly controlled asthma.
- Trial name
- PAAL (NCT00860418)
- Testing
- Pediatric Asthma Alert (PAAL), Standard asthma education
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Johns Hopkins University