Clinical trials: Artificial Limbs
Tongue Neoplasms, Tongue Cancer
Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue
This study will fill a scientific gap in the current knowledge providing data for evaluation of the palatal augmentation prosthesis (PAP) as a therapeutic modality post-surgery.
- Conditions
- Tongue Neoplasms, Tongue Cancer, Oral Cancer
- Trial name
- PGSRT (NCT02584270)
- Testing
- Palatal Augmentation Prosthesis (PAP), Articulation Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Osteoarthritis
The Press Fit Condylar (P.F.C.) Sigma Rotating Platform (RP) TC3 Revision Knee in Revision Knee Arthroplasty
The purpose of this study is to evaluate the long-term clinical and functional performance of the P.F.C. Sigma Rotating Platform TC3 knee system in revision knee surgery and to determine whether the implant design results in a…
- Trial name
- TC3 (NCT00733681)
- Testing
- PFC Sigma RP TC3 Revision knee system
- Where
- 9 sites in France, Germany and 2 more
- Volunteers
- 181 people
- Sponsor
- DePuy International
Infection of Total Knee Joint Prosthesis, Aseptic Loosening of Prosthetic Joint
Surgical / Economic Effect of the Aquamantys System in Blood Management for Aseptic and Septic Revision TKA
To assess the surgical and economic effectiveness of the Aquamantys System in managing intra- and post-operative blood loss, and reducing transfusion needs in patients undergoing both aseptic and septic revision total knee…
- Trial name
- NCT02266407
- Testing
- Aquamantys System
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Non-inflammatory Degenerative Joint Disease, Osteoarthritis
Ceramic On Ceramic (COC) 36mm PAS IDE Rollover Subjects; Ceramic Acetabular Bearing With Ceramic Femoral Head in Total Hip Replacement
This study is intended to gather medium (5- to 7-years) and long-term (minimum 8- to 10-years) information regarding the performance and safety of the commercially available 36mm CERAMAX® Ceramic on Ceramic (COC) Total Hip System…
- Conditions
- Non-inflammatory Degenerative Joint Disease, Osteoarthritis, Avascular Necrosis, Post-Traumatic Osteoarthritis of Hip
- Trial name
- COC36mmPAS (NCT02096198)
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis
"Score Infectivity" During Reoperation on Total Hip or Knee Prosthesis
The hip or knee is a validated treatment of end-stage osteoarthritis, and these interventions commonly make a significant improvement in the quality of life of patients. Infection can occur in 1-5% of cases.
- Trial name
- NCT02467764
- Testing
- Retrospective study
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Wear of Articular Bearing Surface of Prosthetic Joint, Migration of Implant
Migration of CS vs CR Insert in TKA Using RSA
Background: The choice whether or not to preserve the posterior cruciate ligament (PCL) in total knee arthroplasty (TKA) is coupled to the us of a PCL-retaining (CR) or a condylar (CS) insert.
- Trial name
- CS vs CR RSA (NCT05936593)
- Testing
- Condylar Stabilizing (CS) insert, Cruciate Retaining (CR) insert
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Patient Satisfaction
This Study Will Assess Whether the Treatment Provided by Dentist is Successful in Meeting the Expectations of Patient by Asking Questions Related to Aesthetics, Chewing Ability, Comfort and Phonetics Before and After Providing Treatment and the Patient Will Tell Through Visual Analog Scale
This study aims to assess patient satisfaction after receiving porcelain-fused-to-metal fixed dental prostheses. Patients will be asked about their expectations before treatment and their satisfaction afterward.
- Trial name
- NCT07100678
- Testing
- Porcelain-Fused-to-Metal Fixed Dental Prosthesis
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Khyber College of dentistry
Hallux Rigidus, Hallux Limitus
Short Term Follow-up of Patient Implanted With the Metatarso-Phalangeal Prosthesis METIS®
The great toe is vital for normal, pain free ambulation. Decreased function associated with osteoarthritis of the first matatarsal phalangeal joint (MTP I) often called Hallux Rigidis or Hallux Limitus leading to a painful great…
- Conditions
- Hallux Rigidus, Hallux Limitus, Hallux Valgus, Osteoarthritis
- Trial name
- NCT01284985
- Where
- 4 sites in Czechia, Netherlands and 2 more
- Volunteers
- 60 people
- Sponsor
- Integra LifeSciences Services
Hypothermia
Observational Examination of Thermoregulation in Total Joint Arthroplasty
Total joint patients have poor outcomes with infection since they are having permanent hardware implanted. Infection prevention in this group is therefore critical and a major source of discussion in both the orthopedic and…
- Trial name
- NCT02225743
- Testing
- Observation Of Temperature
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Penile Implantation, Infections
Next Generation Sequencing Versus Traditional Cultures for Clinically Infected Penile Implants: Impact of Culture Identification on Outcomes
Randomized prospective study to evaluate next generation sequencing (NGS) and standard-of-care culture for clinically infected penile implants and to compare outcomes with identification of microbes.
- Trial name
- NCT05287438
- Testing
- Next-Generation DNA Sequencing, Standard Culture
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- MicroGenDX
Indications for a Total Hip Prosthesis
Primary Birmingham Hip Resurfacing Arthroplasty Using a Metal-on-Metal Couple in the Young Active Patient
To prospectively obtain data about the clinical and radiological results of the resurfacing technique as primary hip prosthesis in young active patients
- Trial name
- NCT00285948
- Testing
- Primary Birmingham hip resurfacing arthroplasty using a metal-on-metal couple
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- University Hospital, Ghent
Upper Limb Amputation Above Elbow, Upper Limb Amputation Below Elbow
Long-Term Stability of the Glide Control Strategy
This research is intended to test whether the prescription of the Glide prosthesis control system reduces the burden of use for both patients and their clinical care team as compared to use of Pattern Recognition-based advanced…
- Trial name
- NCT07222085
- Testing
- Glide Control System, Pattern Recognition System
- Where
- 10 sites in United States
- Volunteers
- 12 people
- Sponsor
- Infinite Biomedical Technologies
Osteoarthritis Thumb
Post Market Clinical Follow-Up TOUCH® CMC 1
Because severe pain, weakened pinch and grip strength produce functional disabilities, the basal joint of the thumb is the most common site of surgical reconstruction in the upper limb due to OA.
- Trial name
- NCT06546306
- Testing
- TOUCH® CMC 1
- Where
- 6 sites in France
- Volunteers
- 216 people
- Sponsor
- Keri Medical SA
Vestibular Diseases, Peripheral Neuropathies
Use of a Vibrotactile Sensory Prosthesis in Patients With Postural Imbalance and Spatial Disorientation
The investigators propose to explore the hypothesis that vibrotactile channels for indicating spatial orientation can be exploited as a sensory prosthesis.
- Conditions
- Vestibular Diseases, Peripheral Neuropathies, Proprioceptive Disorders, Hemispatial Neglect
- Trial name
- NCT00146952
- Testing
- Vibrotactile feedback
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Implant Complication, Implant Infection
Local Antibiotics for Breast Implants
The BREAST-AB Trial is a multi-center, randomized, double blind, placebo-controlled trial investigating the efficacy of local application of gentamicin, vancomycin and cefazolin in decreasing all-cause implant explantation after…
- Conditions
- Implant Complication, Implant Infection, Implant Site Infection, Implant Capsular Contracture
- Trial name
- BREAST-AB (NCT04731025)
- Testing
- Gentamicin, Cefazolin and Vancomycin
- Where
- 8 sites in Denmark
- Volunteers
- 1,003 people, healthy volunteers welcome
- Sponsor
- Mikkel Herly
Prosthetic Joint Infection, Prosthetic Infection
Susceptibility Testing of Biofilm to Guide Treatment of Periprosthetic Joint Infections
The overall purpose of this clinical treatment research project is to explore novel diagnostics that can guide the treatment of infections associated to orthopaedic implants, in order to improve patient outcomes and reduce the…
- Conditions
- Prosthetic Joint Infection, Prosthetic Infection, Hip Prosthesis Infection, Knee Prosthesis Infection
- Trial name
- NCT04488458
- Testing
- MIC or MBEC+MIC based treatment algorithm
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Capsular Contracture, Implant
Ultrasound Guided Treatment of Steroids for Capsular Contracture in Patients With Reconstructed/Augmented Breast
Ultrasound guided treatment of steroids for capsular contracture in patients with reconstructed/augmented breast
- Trial name
- NCT03171974
- Testing
- Dexamethasone, US
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Amputation
Clinical Feasibility of the IMES Transradial Prosthesis
This study will evaluate the feasibility of using implanted myoelectric sensors (IMES) to control a transradial prosthesis
- Trial name
- NCT04936789
- Testing
- IMES
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- Össur Iceland ehf
Total Knee Arthroplasty, Knee Disease
Open Label Study to Collect Clinical Data to Document Clinical Performance and Safety in Total Knee Arthroplasty
The purpose of this study is to evaluate clinical performance and safety in total knee arthroplasty using HLS implants.
- Conditions
- Total Knee Arthroplasty, Knee Disease, Total Knee Replacement, Osteo Arthritis Knee
- Trial name
- NCT04727060
- Testing
- patient with knee arthroplasty
- Where
- France
- Volunteers
- 2,146 people
- Sponsor
- Corin
Partial Edentulism, Disorder of Prostheses and Implants
Survival of Implant-Supported All-Ceramic Prostheses
The purpose of this research study is to identify reasons that cause an all-ceramic bridge to fracture which include the thickness of the bridge material, the type of bridge material and the bite force of the person.
- Conditions
- Partial Edentulism, Disorder of Prostheses and Implants, Dental Prosthesis Failure
- Trial name
- NCT01729858
- Testing
- Ceramic-Ceramic, Metal-Ceramic
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Florida
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