Clinical trials: Arthrosis of First Carpometacarpal Joint
Osteoarthritis, Tendinopathy
Ketorolac in Upper Extremity Tendinopathy and Arthropathy
Osteoarthritis (OA) and inflammatory conditions of the tendons and joints of the shoulder, elbow, hand, and wrist are common yet disabling diseases.
- Conditions
- Osteoarthritis, Tendinopathy, Arthropathy
- Trial name
- NCT05292339
- Testing
- Triamcinolone injection to the shoulder, elbow, wrist, or hand, Ketorolac injection to the shoulder, elbow, wrist, or hand
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Emory University
Early Stage Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC)for Osteoarthritis of the First CarpoMetacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion)in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01961570
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Articulinx
Thumb Osteoarthritis, Hand Osteoarthritis
Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatment
Aim: We aim to determine and compare the efficiency of single dose intra-articular (IA) platelet rich plasma (PRP) and corticosteroid (CS) injections for the treatment of first carpometacarpal joint osteoarthritis (1.
- Conditions
- Thumb Osteoarthritis, Hand Osteoarthritis, Platelet Rich Plasma, Corticosteroid
- Trial name
- NCT06657300
- Testing
- PRP, Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Antalya Training and Research Hospital
Osteoarthritis Thumb, Arthrosis of First Carpometacarpal Joint
CMC I Stability Intraoperative
The goal of the current study is to objectively measure intraoperative the initial thumb stability after trapezium removal when performing trapeziectomy, alone or in combination with suspension and tendon interposition and to…
- Conditions
- Osteoarthritis Thumb, Arthrosis of First Carpometacarpal Joint, Joint Instability
- Trial name
- NCT03687775
- Testing
- Stability assessment
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Schulthess Klinik
Osteoarthritis Thumb, Osteoarthritis, Knee
Analysis of Articular Biomarkers From Osteoarthritic Thumb Basal Joints
The study project aims at examining molecular markers in synovial fluid, bone and articular cartilage from osteoarthritic thumb basal joints.
- Conditions
- Osteoarthritis Thumb, Osteoarthritis, Knee, Metabolic Disease
- Trial name
- NCT06370312
- Testing
- Trapeziectomy
- Where
- 2 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- Region Skane
Arthrosis of First Carpometacarpal Joint
Short-term Recovery After Trapeziectomy and TMC Prosthesis: a Diary Study
Rationale: The trapeziometacarpal (TMC) joint is one of the most common areas in the hand and wrist to develop osteoarthritis (OA).
- Trial name
- THUMB Diary (NCT06654349)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Rhizarthrosis
Effectiveness and Safety of Breeded Leech for Symptomatic Primary Arthrosis of the First Carpometacarpal Joint
In this trial the investigators want to prove the efficacy and safety of a one-time topical leech application at patients with symptomatic primary arthrosis of the first carpometacarpal joint in comparison to the standard therapy…
- Trial name
- NCT03020368
- Testing
- Leeches, Diclofenac
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Charite University, Berlin, Germany
Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC) for Osteoarthritis of the First Metacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion) in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01973803
- Where
- 3 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Articulinx
Osteoarthritis
Double-Blind,Randomized,Placebo-Controlled Efficacy & Safety Study of EUFLEXXA™ for Treatment of OA of the First CMC
This multicenter, double-blind, randomized, parallel-group, active-controlled trial will be performed in approximately 80 subjects with chronic idiopathic osteoarthritis (OA) of the first carpo-metacarpal joint (CMC).
- Trial name
- NCT00423371
- Testing
- sodium hyaluronate
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Ferring Pharmaceuticals
Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis
Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint…
- Conditions
- Thumb Osteoarthritis, Thumb Carpometacarpal Joint Osteoarthritis, Carpometacarpal (CMC) Joint Arthritis, Basal Thumb Osteoartrithis
- Trial name
- BASTION (NCT07569549)
- Testing
- Implantation of trapeziometacarpal prosthesis, Trapeziectomy with Capsuloplasty
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Uppsala University
Osteoarthritis Thumb, Joint Diseases
Touch on One Thumb, RSI on the Other Thumb: Which Surgery Shows Better Results
The study aims to determine whether CMC I arthroplasty using a Touch® implant results in higher patient satisfaction compared to RSI arthroplasty in the medium-term in patients with primary thumb osteoarthritis.
- Conditions
- Osteoarthritis Thumb, Joint Diseases, Musculoskeletal Diseases or Conditions, Osteoarthritis
- Trial name
- NCT05849506
- Testing
- Touch® Prosthesis
- Where
- Switzerland
- Volunteers
- 14 people
- Sponsor
- Schulthess Klinik
Osteoarthrosis, Ultrasound
Ultrasound Findings of Thumb Muscles in 1st Carpometacarpal Osteoarthritis
Carpometacarpal (CMC) joint osteoarthritis is a disorder that is estimated to affect more than one-third of postmenopausal women, leading to decreased muscle strength, reduced joint range of motion, and pain.The pathogenesis of…
- Trial name
- NCT06600464
- Testing
- Ultrasound, Assessment of Muscle Strength in Both Hands, Assessment of Pain Threshold
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis Compared to LRTI (GRIP 2)
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the first CMC joint in the hand compared to LRTI.
- Trial name
- GRIP 2 (NCT03247439)
- Testing
- Cartiva
- Where
- 9 sites in United States, United Kingdom
- Volunteers
- 74 people
- Sponsor
- Cartiva, Inc.
Osteoarthritis
Thumb Muscle Thickness and Strength in CMC Osteoarthritis
A total of 34 patients aged between 50-80 years, diagnosed with first carpometacarpal joint osteoarthritis based on hand radiographs taken within the last 3 months, will be included in the study from the Physical Therapy and…
- Trial name
- NCT06730698
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Beylikduzu State Hospital
Osteoarthritis
Safety and Effectiveness of Cartiva Implant in the Treatment of First CMC Joint Osteoarthritis
This study will evaluate whether Cartiva is an effective treatment for individuals with osteoarthritis of the CMC joint in the hand.
- Trial name
- GRIP (NCT02391506)
- Testing
- Cartiva
- Where
- 9 sites in Canada, United Kingdom
- Volunteers
- 50 people
- Sponsor
- Cartiva, Inc.