Clinical trials: Arthroplasty, Hip Revision
Pinnacle Metal-on-Metal, Revised Pinnacle Metal-on-Metal
Pinnacle Metal-on-Metal 522 Post-Market Surveillance Study
The purpose of this clinical study is to evaluate blood metal ion levels as a function of time of implantation for the Pinnacle Acetabular MoM system.
- Conditions
- Pinnacle Metal-on-Metal, Revised Pinnacle Metal-on-Metal, Adverse Local Tissue Reaction, Metal Ions
- Trial name
- NCT01828801
- Testing
- Pinnacle Metal-on Metal
- Where
- 8 sites in United States
- Volunteers
- 276 people
- Sponsor
- DePuy Orthopaedics
Revision of Total Hip Arthroplasty
Effectiveness of Intraoperative Cell Salvage in Aseptic Revision Total Hip Arthroplasty.
Intraoperative cell salvage is an important measure of patient blood management but its effectiveness in patients undergoing revision total hip arthroplasty remains unclear.
- Trial name
- NCT05237830
- Testing
- Use of Cell Salvage in revision of total hip arthroplasty
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- University of Liege
Infection
Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty
The purpose of this study is to compare infection rates when patients, elected for primary or aseptic revision THA / TKA, have a single intravenous antibiotic dose versus one single intravenous antibiotic dose in combination with…
- Trial name
- NCT04399642
- Testing
- Arthroplasty
- Where
- Canada
- Volunteers
- 1,832 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Orthopedics, Postoperative Complications
Old Blood and Postoperative Complications
The investigators sought to examine the effects of 'old' red blood cells on mortality and morbidity of patients who undergoing revision hip replacement arthroplasty.
- Conditions
- Orthopedics, Postoperative Complications, Red Blood Cells
- Trial name
- NCT02575820
- Testing
- Old red blood cells transfusion, New red blood cells transfusion
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Total Hip Replacement, Arthroplasty Complications
REVISITS: Revision Single or Two Stage Surgery
Hip replacement surgery is common, with over 60,000 cases in Canada annually. After hip replacement, about 1-2% patients develop a deep infection in their artificial hip implant, called a periprosthetic joint infection (PJI).
- Trial name
- REVISITS (NCT03741296)
- Testing
- Single stage revision, Two-stage revision
- Volunteers
- 110 people
- Sponsor
- Unity Health Toronto
Hip Arthroplasty, Knee Arthroplasty
CT for Diagnosis of Implant Stability in Revision Arthroplasty
All patients over 18 who undergo a revision of hip or knee arthroplasty will be included. Patients undergo a CT of the hip joint. A radiologist will mark the presence of cysts and bone loss and will assess implant stability.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Osteolysis
- Trial name
- NCT00367289
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Revision Hip Prosthesis System in adult participants…
- Conditions
- Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint, Prostheses-related Infections, Joint Instability
- Trial name
- NCT07653295
- Testing
- Tıpmed™ Revision Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Avascular Necrosis of Hip, Degenerative Hip Joint Disease
Revision Total Hip Replacement Arthroplasty and Hematologic Variables
Revision total hip replacement arthroplasty is a surgery having intra- and postoperative substantial blood loss. The investigators will investigate the relationship between the various hematologic variables and postoperative…
- Trial name
- NCT02951741
- Testing
- RTHRA group
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Bundang Hospital
Hip Arthroplasty
A Comparison of Two Type of Stems in Revision Hip Arthroplasty
This study compares two different hip stem components. Both hip stems used in this study allow the femur bone to attach and grow into them for stability.
- Trial name
- NCT00253838
- Testing
- Restoration HA stem, Solution stem
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Arthroplasty
Heidelberg Registry for Hip and Knee Joint Implants and Revisions
The Endoprosthesis Registry Heidelberg (EPR-HD) is a clinical registry designed to systematically collect and analyze data from patients undergoing primary implantation or revision surgery of artificial hip and knee joints.
- Trial name
- EPR-HD (NCT06850818)
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- University Hospital Heidelberg
Infection, Hip Joint Replacement
Cementless One-stage Revision of the Chronic Infected Hip Arthroplasty
The investigators hypothesise that cementless one-stage exchange revision surgery can be performed in patients with chronically infected hip replacement with substantial benefits for the patients, in terms of fast rehabilitation…
- Trial name
- CORIHA (NCT01015365)
- Testing
- Cementless one-stage surgical revision
- Where
- 8 sites in Denmark
- Volunteers
- 56 people
- Sponsor
- University of Aarhus
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Antibiotic Prophylaxis in Primary Joint Arthroplasty of the Hip and Knee.
A retrospective study will be performed to compare the incidence of revision procedures performed for the treatment of postoperative periprosthetic joint infection (PJI) between patients treated with a single preoperative…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Antibiotic Prophylaxis
- Trial name
- NCT03348254
- Testing
- Single shot antibiotic prophylaxis, Multiple shot antibiotic prophylaxis
- Where
- Netherlands
- Volunteers
- 242,179 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Developmental Dysplasia of the Hip, Acetabular Bone Loss
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Total hip arthroplasty (THA) in patients with complex acetabular anatomy can be challenging because of abnormal bone structure, deformity, or bone loss.
- Conditions
- Developmental Dysplasia of the Hip, Acetabular Bone Loss, Acetabular Fracture
- Trial name
- NCT07904637
- Testing
- Conventional Imaging-Based Preoperative Planning, CT-Based 3D-Printed Pelvic Model-Assisted Planning
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Arthroplasty, Replacement, Hip
MARS MRI in Revision THA With a Ceramic Femoral Head and Titanium Sleeve
Revision total hip replacement using a ceramic head utilizes a titanium sleeve which introduced another articulation into the system that may lead to a local soft tissue reaction.
- Trial name
- NCT05686915
- Testing
- MARS MRI, Titanium Labs, Cobalt Labs
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Colorado Joint Replacement
Peri-Prosthetic Joint Infection
IP-coated Revision Hip Implants
The primary aim of the clinical investigation is to demonstrate the efficacy of a silver-based antimicrobial coating on hip implants in the reduction of periprosthetic infections in revision hip arthroplasty due to periprosthetic…
- Trial name
- HIPrevision (NCT06737809)
- Testing
- IP Plasmafit® Revision cup (and stem) system
- Where
- 2 sites in Germany, Poland
- Volunteers
- 268 people
- Sponsor
- Aesculap AG
Prosthesis-related Infections, Wound Complications
Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
The purpose of this study is to determine the efficacy of a negative pressure wound therapy (NPWT) system after revision total knee and hip arthroplasty in patients at high risk for infection.
- Conditions
- Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02127281
- Testing
- Prevena
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Cleveland Clinic
Total Hip Arthroplasty (THA), Antibiotic Prophylaxis
Infection-related Revision Rates After Single-dose Versus Multiple-dose Antibiotic Prophylaxis in Primary Hip and Knee Arthroplasty: a Comparative Implementation Study.
Prosthetic Joint Infection (PJI) is a significant issue in joint replacement surgeries, causing additional surgeries and substantial healthcare costs.
- Conditions
- Total Hip Arthroplasty (THA), Antibiotic Prophylaxis, Revision Arthroplasty, Total Knee Arthroplasty
- Trial name
- REVISE (NCT07053943)
- Where
- Netherlands
- Volunteers
- 70,000 people
- Sponsor
- JointResearch
Aseptic Loosening, Arthroplasty Complications
Total Hip Arthoplastry Revision by Dual-mobility Acetabular Cup Cemented in a Metal Reinforcement
Total hip arthroplasty (THA) requires bone reconstruction in case of severe acetabular injury, with risk of dislocation, especially postoperatively.
- Trial name
- PTH (NCT03680443)
- Testing
- assembly in THA revision
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Total Hip Arthroplasty (THA), Revision Hip Arthroplasty
Cementation of Cup and the Risk of Second Revision
Background: The fixation method of the acetabular component during the primary total hip arthroplasty (THA) affects the surgical techniques implemented in the revision surgery and may influence the risk of second revision.
- Trial name
- NCT06583382
- Volunteers
- 60,000 people
- Sponsor
- Bispebjerg Hospital
Arthroplasties, Hip Replacement
REDAPT Retrospective-Prospective Modular Stem Study
A Retrospective-Prospective Study of REDAPT Revision Femoral System Modular Stem is a post-market, retrospective-prospective, multi-center, single arm, consecutive series study design to provide data on the post market…
- Trial name
- NCT02661620
- Testing
- REDAPT Revision Femoral System modular stem
- Where
- 5 sites in United States, Belgium and 1 more
- Volunteers
- 140 people
- Sponsor
- Smith & Nephew, Inc.