Clinical trials: Arteriovenous Graft
Renal Dialysis
Design the Home Care Platform for the Monitoring of A Hemodialysis Arteriovenous Graft by Intelligent Physiological Signal
Most patients with end-stage renal disease require hemodialysis. An arteriovenous fistula (AVF) or a prosthetic arteriovenous graft (AVG) is the preferred accesses for this.
- Trial name
- NCT00702559
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Far Eastern Memorial Hospital
Neointimal Hyperplasia, Dialysis Access Malfunction
A Prospective, Randomized Controlled Trial of Stent Graft and Drug Coated Balloon Treatment for Recurrent Cephalic Arch Stenosis in Dysfunctional Arteriovenous-venous Fistula
Arteriovenous Fistula (AVF) is a surgically created circuit used for hemodialysis in patient with End Stage Renal Disease (ESRD).
- Trial name
- PREDATOR (NCT05360394)
- Testing
- Paclitaxel Coated Balloon, Paclitaxel Coated Balloon and Stent Graft
- Where
- 2 sites in Australia, Singapore
- Volunteers
- 80 people
- Sponsor
- Singapore General Hospital
Hyperplasia, Stenosis
Stent vs. Angioplasty for Treatment of Thrombosed AV Grafts: Long-Term Outcomes
Arteriovenous grafts are used as the vascular access in 40-50% of hemodialysis patients. Grafts are prone to recurrent stenosis (narrowing) and thrombosis (clotting).
- Trial name
- NCT00496639
- Testing
- angioplasty, stent placement
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- National Kidney Foundation, United States
Venous Stenosis, Venous Occlusion
The Merit WRAPSODY AV Access Efficacy Study (WAVE)
The purpose of the study is to demonstrate the safety and efficacy of the Merit WRAPSODY Endovascular Stent Graft for treatment of stenosis or occlusion within the dialysis access outflow circuit
- Trial name
- WAVE (NCT04540302)
- Testing
- Merit WRAPSODY Endovascular Stent Graft, PTA
- Where
- 43 sites in United States, Brazil and 2 more
- Volunteers
- 357 people
- Sponsor
- Merit Medical Systems, Inc.
Brachial Plexus Injury
Arteriovenous Loop Graft for Free Functional Gracilis Transfer in Brachial Plexus Surgery
Free functional muscle transfer (FFMT) using the gracilis muscle as a donor muscle has become a standard treatment for reconstructing late-onset brachial plexus injuries.
- Trial name
- NCT06437990
- Testing
- Arteriovenous loop graft
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Siriraj Hospital
Decision Tree Analysis
Clinical Decision Tree Analysis of Hemodialysis Arteriovenous Access Choices and Creations - a Multiple-center Retrospective Cohort Study
Our study aim was to utilize a decision tree analysis (DTA) model to gain insight into the decision-making process within a multiple-center cohort.
- Trial name
- NCT06364449
- Testing
- No intervention
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dialysis Access Malfunction
Continued Access Study VIG Anastomotic Connector
The continued access study of the InterGraft Venous Anastomotic Connector (Venous InterGraft Continued Access Study, or 'VIG-CAS') allows for continued enrollment of subjects while the marketing application is being prepared and…
- Trial name
- VIG-CAS (NCT05448950)
- Testing
- VIG Continued Access Study
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- Phraxis, Inc.
End Stage Renal Disease, Hemodialysis Vascular Access Failure
Reduction of Plasma Free VEGF-A Using Low-dose Bevacizumab in Hemodialysis Patients
The primary purpose of this pilot study is to assess the pharmacokinetic profile of low-dose bevacizumab and its effectiveness in reducing plasma free VEGF-A levels safely in hemodialysis patients.
- Trial name
- NCT02695641
- Testing
- 1.25mg bevacizumab, 2.50mg bevacizumab
- Sponsor
- Mayo Clinic
Arteriovenous Graft
LineMatrix® Biological Vascular Graft for the Creation of Arteriovenous Graft
The study is planned to be conducted at multiple centers, with an intended enrollment of 326 subjects. Protocol-eligible subjects will be randomized in a 1:1 ratio to either the investigational group or the control group.
- Trial name
- NCT07773051
- Testing
- LineMatrix® Biological Vascular Graft, GORE-INTERING®
- Where
- 12 sites in China
- Volunteers
- 326 people
- Sponsor
- Longhua Hospital
Renal Failure
Randomized Fistula Study
The primary objective of this study is to compare two treatment strategies for establishing dialysis access in patients with unsuitable forearm veins for the standard forearm primary radio-cephalic arteriovenous fistula also…
- Trial name
- NCT00808561
- Testing
- Group 1: Alternative Fistula, Group 2: Forearm AV Graft
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Pittsburgh
Hemodialysis Access Failure
Immediate-access Arteriovenous Versus Standard Arteriovenous Grafts in Hemodialysis Patients
Arteriovenous fistulae (AVF) are considered the main access for hemodialysis (HD). Arteriovenous grafts (AVGs) are an alternative access modality in patients with exhausted native venous access.
- Trial name
- NCT04388397
- Testing
- Arteriovenous Grafts
- Where
- 2 sites in Egypt
- Volunteers
- 477 people
- Sponsor
- Egyptian Biomedical Research Network
Peripheral Artery Disease, Arteriovenous Fistula Stenosis
FLEX Arteriovenous Access Registry
Evaluation of the FLEX Vessel Prep system combined with angioplasty in the treatment of arteriovenous access stenosis.
- Conditions
- Peripheral Artery Disease, Arteriovenous Fistula Stenosis, Arteriovenous Graft Stenosis
- Trial name
- NCT04070365
- Testing
- FLEX Vessel Prep System followed by angioplasty
- Where
- 10 sites in United States
- Volunteers
- 114 people
- Sponsor
- VentureMed Group Inc.
Arteriovenous Fistula, Arteriovenous Graft
Access Creation for Hemodialysis: Association With Structural Changes of the Heart
The purpose of this study is to determine if the creation of a fistula or a graft plays a role in the development of heart disease for patients undergoing hemodialysis
- Conditions
- Arteriovenous Fistula, Arteriovenous Graft, Left Ventricular Hypertrophy, Brain Natriuretic Peptide
- Trial name
- NCT00368147
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Ottawa Hospital Research Institute
Stenosis, Restenosis
Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft in AV Graft Patients (AVeVA)
The objective of this study is to assess the safety and effectiveness of the COVERA™ Vascular Covered Stent for the treatment of stenotic lesions in the upper extremity venous outflow of the Arteriovenous (AV) access circuit.
- Trial name
- AVeVA (NCT02790606)
- Testing
- Covera(TM) Vascular Covered Stent
- Where
- 16 sites in United States
- Volunteers
- 110 people
- Sponsor
- C. R. Bard
Peripheral Arterial Disease, Arterio-venous Fistula
Serranator® Alto Post Market Clinical Follow Up (PMCF) Study
The objective of this registry is to collect observational data under local standard of care and evaluate safety and performance of the Serranator® Alto in treatment of peripheral artery disease (PAD), or dysfunctional native or…
- Conditions
- Peripheral Arterial Disease, Arterio-venous Fistula, Arteriovenous Graft
- Trial name
- NCT03538392
- Testing
- Serranator® Alto
- Sponsor
- Cagent Vascular LLC
Hyperplasia, Chronic Renal Failure
Prevention of Vascular Access Graft Failure in Patients With Chronic Renal Failure Requiring Hemodialysis
The purpose of this study is to determine the effect of recipient vein pretreatment of edifoligide (E2F Decoy), compared to placebo, on graft/recipient vein stenosis in polytetrafluoroethylene (PTFE) vascular access grafts placed…
- Trial name
- NCT00086164
- Testing
- edifoligide (E2F Decoy)
- Where
- 21 sites in United States
- Sponsor
- Anesiva, Inc.
Hemodialysis Access
Safety of Vascugel Treatment After Creation of Arteriovenous Access for Hemodialysis Use
Vascugel™ is safe when placed at the anastomotic site at the time of surgery during creation of an AV graft or fistula for hemodialysis access.
- Trial name
- NCT00479180
- Testing
- Vascugel
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Pervasis Therapeutics, Inc
Dialysis Access Dysfunction, Endovascular Procedure
A Neuromodulation Auditory System to Optimize Patient Experience During Dysfunctional Dialysis Access Endovascular Procedures
Peri-procedural stress is a common challenge in interventional radiology that can negatively impact patient tolerance and the overall procedural experience.
- Conditions
- Dialysis Access Dysfunction, Endovascular Procedure, Patient Experience, Neuromodulation
- Trial name
- NCT07467642
- Testing
- Neuromodulation auditory system
- Where
- 2 sites in Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital
Stenosis of Arteriovenous Dialysis Fistula, Arteriovenous Graft Stenosis
Prospective Randomized Trial Comparing DEB Versus Conventional PTA for the Treatment of Hemodialysis AVF or AVG Stenoses
A prospective randomized trial comparing the efficacy of drug eluting balloon angioplasty versus conventional percutaneous transluminal angioplasty balloon for the treatment of hemodialysis arterio-venous fistula or…
- Trial name
- DEBAPTA (NCT01544907)
- Testing
- Conventional PTA, Drug Eluting Balloon (DEB)
- Where
- Singapore
- Volunteers
- 125 people
- Sponsor
- Singapore General Hospital
Arteriovenous Graft, Arteriovenous Fistula
Validation of Arterio Venous Access Stage (AVAS) Classification
VAVASC trial is an observational multicentre study. The aim of this trial is to validate AVAS (arteriovenous vascular access stage) classification.
- Conditions
- Arteriovenous Graft, Arteriovenous Fistula, Dialysis Access Malfunction, Kidney Failure
- Trial name
- VAVASC (NCT04796558)
- Testing
- AVAS Classification
- Where
- Czechia
- Volunteers
- 800 people
- Sponsor
- Vascular surgery, University hospital Královské Vinohrady, Prague