Clinical trials: Arterial Occlusion
Coronary Artery Disease
Gadobutrol / Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Subjects being evaluated for suspected or known Coronary artery Disease (CAD) based on signs and/or symptoms, will be invited to participate in the study.
- Trial name
- GadaCAD 2 (NCT01890434)
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875)
- Where
- 24 sites in United States, Australia and 2 more
- Volunteers
- 478 people
- Sponsor
- Bayer
Coronary Artery Disease, Myocardial Ischemia
The eSVS® Mesh Randomized Post-Market Study
The purpose of this study is to evaluate patency rates of the external Saphenous Vein Support (eSVS) Mesh Saphenous Vein Grafts (SVG) and Control SVG at 3-6 months and 24 months.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT01462721
- Testing
- eSVS® Mesh
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Kips Bay Medical, Inc.
Critical Limb Ischemia
External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality
In this clinical research study the investigators will test the efficacy of an innovative, non-invasive methodology to reduce mortality and lower limb loss among high-risk medically-underserved patients with cardiovascular…
- Trial name
- ArtAssist (NCT02054416)
- Testing
- ArtAssist© Device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Temple University
Coronary Artery Disease, Hypertension
Effect of Intensive Blood Pressure Control on Progression of Coronary Atherosclerosis: Randomized Evaluation by Intravascular Ultrasound
The purpose of this study is to evaluate the effect of intensive blood pressure control compared to standard blood pressure control on progression of coronary atherosclerosis by intravascular ultrasound in hypertensive patients…
- Trial name
- PREVUS (NCT01230216)
- Testing
- control systolic blood pressure less than 120 mmHg, control systolic blood pressure less than 140 mmHg
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Takeshi Morimoto
ICAS - Intracranial Atherosclerosis
IntraCranial Angiography-derived Fraction Flow-guided Percutaneous Transluminal Angioplasty and Stenting Versus Medical Therapy (ICAS-MT)
A multicenter, open-label, blinded-endpoint, prospective, randomized controlled clinical trial with an "all comers" design.
- Trial name
- NCT05974033
- Testing
- Stenting plus medical therapy, Medical therapy alone
- Volunteers
- 536 people
- Sponsor
- Changhai Hospital
Polyvascular Disease, Atherosclerosis
Clinical Register Studying the therApeutic Patient Population With Multifocal Atherosclerosis
Аn international, multicenter, non-interventional real-life clinical practice Register studying the Actual therapeutic patient population with Multifocal Atherosclerosis in the Russian Federation and Eurasian countries
- Conditions
- Polyvascular Disease, Atherosclerosis, Atherosclerosis Generalized, Cardiovascular Diseases
- Trial name
- KAMMA (NCT05189847)
- Where
- Russia
- Volunteers
- 3,059 people
- Sponsor
- Eurasian Association of Therapists
Coronary Artery Disease, Cognitive Impairment
Cerebral Oxygenation and Neurological Functioning After Cardiac Surgery
The overall goal of this research program is to determine quantitative predictors of quantitative long-term neurological functioning following different cardiac surgery procedures.
- Conditions
- Coronary Artery Disease, Cognitive Impairment, Delirium
- Trial name
- CONFUSE (NCT04081649)
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Dr. Gordon Boyd
Coronary Artery Disease, Arterial Occlusive Diseases
The ENDEAVOR II Clinical Trial: The Medtronic Endeavor Drug Eluting Coronary Stent System in Coronary Artery Lesions
To demonstrate the safety and efficacy of the Driver Coronary Stent coated with 10 mcg/mm ABT-578 compared to the uncoated Driver Stent for the treatment of single de novo lesions in native coronary arteries 2.25-3.5 mm in…
- Conditions
- Coronary Artery Disease, Arterial Occlusive Diseases, Coronary Disease, Coronary Arteriosclerosis
- Trial name
- ENDEAVOR II (NCT00614848)
- Testing
- Endeavor drug eluting coronary stent
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Medtronic Vascular
Hemorrhage, Vascular Injury
A Transparent Elasticized Adhesive Occlusive Compression Bandage for Use as an Arterial Tourniquet
This cross-over study of twenty five (anticipated) healthy human subjects will utilize two active control devices, and two different widths of the investigational device.
- Trial name
- NCT02592655
- Testing
- Pneumatic Tourniquet, One Windlass Tourniquet, Two Windlass Tourniquets
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Marcus Migura
Coronary Artery Disease
A Low-dose Radiation and Contrast Agent Exposure Protocol for Coronary CTA in Diabetic Patients
To assess diagnostic accuracy,image quality and renal safety of a double low-dose coronary CTA protocol at coronary artery evaluation in patients with diabetes by using invasive coronary angiography(ICA) as the reference method…
- Trial name
- NCT04342455
- Testing
- double-low scanning
- Where
- China
- Volunteers
- 400 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Cardiovascular Diseases, Atherosclerosis
Reduction of Triglycerides in Women on Hormone Replacement Therapy
The purpose of this study is to test the effect of lifestyle intervention on subclinical cardiovascular disease measures in women taking hormone replacement therapy (HRT).
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Postmenopause, Heart Diseases
- Trial name
- NCT00023543
- Testing
- Diet, fat-restricted, Exercise
- Where
- United States
- Volunteers
- 508 people
- Sponsor
- University of Pittsburgh
Coronary Artery Disease, Acute Myocardial Ischemia
Reduction of Ischemic Myocardium With Ranolazine-Treatment in Patients With Acute Myocardial Ischemia
The aim of the RIMINI-Trial is to examine the effect of Ranolazine on ischemic myocardium in acute myocardial ischemia. A pilot-trial by Venkatamaran et al.
- Trial name
- RIMINI-Pilot (NCT01797484)
- Testing
- Ranolazine
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Coronary Heart Disease, Angina Pectoris
The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris
The purpose of this study is to determine whether exposure to diesel exhaust (air pollution) has a functional impact on patients with stable angina pectoris.
- Trial name
- NCT00737958
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
Coronary Artery Diseases
Comparison of 18-F Sodium Fluoride Uptake in Culprit Plaques Between Acute Coronary Syndrome and Stable Angina
The purpose of this study is to evaluate the correlations between active calcification and vulnerable plaque.
- Trial name
- NCT01665248
- Testing
- 18-F Sodium Fluoride Uptake in Positron emission tomography
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- CHEOL WHAN LEE, MD, PhD.
Coronary Artery Disease
Feasibility and Safety Study Comparing REG1 Anticoagulation System With Unfractionated Heparin in Elective PCI
The purpose of this study is to determine if it is feasible and safe to use the REG1 Anticoagulation System instead of unfractionated heparin during percutaneous coronary intervention (PCI) in subjects with coronary artery…
- Trial name
- REVERSAL-PCI (NCT00715455)
- Testing
- REG1, Unfractionated Heparin
- Where
- 6 sites in United States, Argentina
- Volunteers
- 26 people
- Sponsor
- Regado Biosciences, Inc.
Peripheral Artery Disease
BEETroot Juice to Reverse Functional Impairment in PAD
The BEET PAD Trial is a multi-centered double-blind randomized clinical trial designed to determine whether beetroot juice, compared to placebo, improves six-minute walk distance at four month follow-up in people with lower…
- Trial name
- BEET PAD (NCT05624125)
- Testing
- Beetroot juice
- Where
- 4 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Peripheral Artery Disease, Intermittent Claudication
Intermittent Negative Pressure to Improve Blood Flow in Patients With Peripheral Artery Disease: Optimal Pulse Pressure Regime
Recent studies have shown that applying intermittent negative pressure (INP) with short negative pressure (-40 mmHg) pulses to the lower extremities increase arterial blood flow velocity and skin blood flow.
- Conditions
- Peripheral Artery Disease, Intermittent Claudication, Lower Extremity Claudication
- Trial name
- NCT03547817
- Testing
- Intermittent negative pressure device
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Oslo University Hospital
Skin Cancer, Skin Diseases
Multi-modal Quantitative Imaging of the Skin
This clinical trial is about evaluating the suitability of multi-modal imaging technology, which covers virtually the entire body, to evaluate the possibility of screening and early detection of disease.
- Conditions
- Skin Cancer, Skin Diseases, Atopic Dermatitis, Psoriasis
- Trial name
- DermaFlow (NCT06989216)
- Where
- 3 sites in Sweden
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- HJN Sverige AB/Neko Health
Serum, Vitamin D
Relationship Between Serum Vitamin D and Atherosclerosis in Hemodialysis Patients
The study aimed to check if there is a link between good vitamin D levels in the blood and subclinical atherosclerosis in people on hemodialysis.
- Conditions
- Serum, Vitamin D, Atherosclerosis, Hemodialysis
- Trial name
- NCT07200804
- Testing
- Measurement of Serum Vitamin D Level, Measurement of Carotid Intima-Media Thickness
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Coronary Artery Disease
2nd International Survey on Interventional Strategies
The study aims to evaluate the decision-making pathways of interventional cardiologists, when assessing patients, presented with stable coronary artery disease.
- Trial name
- NCT04001452
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz