Clinical trials: Arterial Occlusion
Coronary Artery Disease, Radial Artery Occlusion
A Study on the Application of Simple and Improved Radial Artery Compression Method After Transradial Coronary Intervention
The objective of this study was to evaluate the specific effect of a simple modified method of thick gauze (9cm*16cm*8mm) combined with a hemostatic device in the prevention of early radial artery occlusion and other related…
- Trial name
- NCT06787287
- Testing
- Modified compression method
- Where
- China
- Volunteers
- 1,624 people
- Sponsor
- Guozhe Sun
Acute Lower Limb Arterial Occlusion
The ArtixASCEND Study
This study is a post-market, prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the Artix Thrombectomy System in patients with acute lower extremity arterial occlusions.
- Trial name
- NCT07135895
- Testing
- Artix Thrombectomy System
- Where
- 23 sites in United States
- Volunteers
- 250 people
- Sponsor
- Inari Medical
Ischemia, Cerebral, Ischemic Stroke
Detection of Cerebral Ischemia With Artificial Intelligence.
In patients undergoing planned surgery for carotid tromendarterendectomy, a non-invasive device that registers heart rate variability is attached.
- Conditions
- Ischemia, Cerebral, Ischemic Stroke, Artery Occlusion, Artery Carotid Stenosi
- Trial name
- CIDAI-BAS (NCT03919370)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linda Block
Heart Diseases, Coronary Disease
CES1 Carriers in the PAPI Study
This study builds, in part, upon preliminary results generated as part of the Pharmacogenomics Anti-Platelet Intervention (PAPI) Study (NCT00799396).
- Conditions
- Heart Diseases, Coronary Disease, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- NCT03188705
- Testing
- Clopidogrel, Aspirin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Radial Artery Occlusion, Radial Artery Spasm
Radial Access Data in Vascular Interventions Registry
The RADIUS study is a prospective observational registry designed to collect real-world data regarding radial and ulnar artery access in percutaneous vascular interventions.
- Conditions
- Radial Artery Occlusion, Radial Artery Spasm, Vascular Access Complications, Coronary Artery Disease
- Trial name
- RADIUS (NCT07614386)
- Testing
- Radial and Ulnar Artery Access
- Where
- Turkey (Türkiye)
- Volunteers
- 20,000 people
- Sponsor
- Mersin Medicalpark Hastanesi
Radial Artery Occlusion, Cardiac Catheterization
Manual vs Pneumatic Compression to Prevent Radial Artery Occlusion After Transradial Procedures
This study evaluates two commonly used methods of achieving hemostasis after transradial cardiac catheterization: manual compression and pneumatic compression with gradual deflation.
- Trial name
- RADIAL-HEMO (NCT07621185)
- Testing
- Manual Radial Compression, Pneumatic Radial Compression Device
- Where
- Spain
- Volunteers
- 1,168 people
- Sponsor
- Hospital Clinic of Barcelona
Coronary Angiography, Percutaneous Coronary Intervention
Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)
While the reduced hemorrhagic risk of radial access for percutaneous coronary intervention compared to femoral access is well-established, its main complication remains radial artery occlusion, which can occur in up to 30% of…
- Conditions
- Coronary Angiography, Percutaneous Coronary Intervention, Radial Artery Occlusion, Bleeding
- Trial name
- HERA-PCI (NCT06890312)
- Testing
- Administration of heparin after sheath insertion, Administration of heparin prior to sheath insertion
- Where
- France
- Volunteers
- 550 people
- Sponsor
- University Hospital, Strasbourg, France
Acute Ischemic Stroke, Endovascular Thrombectomy
Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)
Acute ischemic stroke (AIS) is a leading cause of mortality and long-term disability worldwide. Among these, stroke caused by large vessel occlusion (LVO) are associated with particularly poor outcomes.
- Conditions
- Acute Ischemic Stroke, Endovascular Thrombectomy, Minocycline, Posterior Circulation
- Trial name
- NCT07594301
- Testing
- Minocycline hydrochloride capsule
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Xiang Luo
Percutaneous Coronary Intervention (PCI), Radial Artery Occlusion
Use of Various Types of Introducers in Conventional Radial Access
The purpose of this intervention study is to compare different types of radial introducers used in traditional radial access in terms of the incidence of complications. The main questions it aims to answer are: 1.
- Conditions
- Percutaneous Coronary Intervention (PCI), Radial Artery Occlusion, Radial Artery Spasm
- Trial name
- TIRE (NCT07572422)
- Testing
- catheterization of the radial artery using an classic introducer, catheterization of the radial artery using an introducer with a standard outer diameter and an outer hydrophilic coating, catheterization of the radial artery using an introducer with a reduced outer diameter and an outer hydrophilic coating
- Where
- 2 sites in Russia
- Volunteers
- 3,307 people
- Sponsor
- Pirogov Russian National Research Medical University
Radial Artery Occlusion
Rivaroxaban Post-Transradial Access for the Prevention of Radial Artery Occlusion
Coronary angiography is performed to evaluate for obstructive coronary artery disease. This is commonly performed via the transfemoral or transradial approach with the latter increasing in frequency.
- Trial name
- CAPITAL-RAPTOR (NCT03630055)
- Testing
- Rivaroxaban 15 MG Oral Tablet [Xarelto]
- Where
- 3 sites in United States, Canada
- Volunteers
- 930 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Diabetic Foot Ulcers (DFU), Lower Extremity Arterial Occlusion
Efficacy and Safety of Cold Atmospheric Plasma Combined With Endovascular Intervention for Diabetic Foot Ulcers With Lower Extremity Arterial Occlusion
The goal of this clinical trial is to evaluate whether cold atmospheric plasma (CAP) combined with endovascular intervention can accelerate wound healing and improve safety outcomes in patients aged 18 to 80 years with diabetic…
- Trial name
- NCT07198061
- Testing
- Cold Atmospheric Plasma (CAP), Infrapopliteal Endovascular Revascularisation, Guideline-Based Standard DFU Care
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shenyang Medical College
Cardiovascular Diseases, Bleeding
Safe and Fast Radial Hemostasis Using Synergistic Strategies: SAFE & FAST Trial
The Safe and Fast Radial Hemostasis using Synergistic Strategies (SAFE \& FAST) trial is an interventional study aimed at reducing the incidence of radial artery occlusion (RAO) rebound bleeding, and the required compression…
- Conditions
- Cardiovascular Diseases, Bleeding, Arterial Puncture, Catheter Complications
- Trial name
- NCT06549842
- Testing
- Heparin, Terumo Radial Band, Vaosband
- Where
- 2 sites in United States, India
- Volunteers
- 451 people
- Sponsor
- Regional Hospital of Scranton
Peripheral Artery Occlusion, Peripheral Arterial Disease
AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)
The study is designed to evaluate the safety and efficacy of the AngioSafe Peripheral CTO Crossing System.
- Trial name
- RESTOR-1 (NCT04663867)
- Testing
- AngioSafe Peripheral CTO Crossing System
- Where
- 18 sites in United States
- Volunteers
- 79 people
- Sponsor
- AngioSafe, Inc.
Shoulder Pain, Tendinopathy
Embolization Treatment of Chronic Refractory Shoulder Tendinopathy
This is a randomized controlled trial in which patients with moderate to severe shoulder pain (Visual Analog Scale (VAS) > 40), in the setting of rotator cuff tendinopathy refractory to conservative treatment, will be enrolled.
- Conditions
- Shoulder Pain, Tendinopathy, Rotator Cuff Tendinitis, Rotator Cuff Tendinosis
- Trial name
- ELECTRC (NCT06095050)
- Testing
- Embolization, Physical Therapy
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Brigham and Women's Hospital
Acute Limb Ischemia, Arterial Occlusion Mesenteric Artery Superior
Post Market Surveillance to Evaluate the Efficacy and Safety of the INDIGO Aspiration System in Japan
This study aims to confirm the safety and effectiveness of the INDIGO Aspiration System in patients requiring immediate treatment for acute lower extremity artery occlusion, acute superior mesenteric artery occlusion, or severe…
- Conditions
- Acute Limb Ischemia, Arterial Occlusion Mesenteric Artery Superior, Acute DVT of Lower Extremity
- Trial name
- JapanIndigoPMS (NCT06446024)
- Testing
- Mechanical aspiration thrombectomy
- Where
- Japan
- Volunteers
- 500 people
- Sponsor
- Penumbra Inc.
Radial Artery Occlusion, Vascular Access
Transulnar Access in Patients With Ipsilateral Radial Artery Occlusion Undergoing Coronary Angiography or Angioplasty
Coronary angiography and angioplasty are commonly performed through the radial artery at the wrist as this approach is associated with fewer bleeding complications and faster recovery.
- Conditions
- Radial Artery Occlusion, Vascular Access, Coronary Artery Disease (CAD)
- Trial name
- ULNART (NCT07380399)
- Where
- 2 sites in Greece
- Volunteers
- 127 people
- Sponsor
- National and Kapodistrian University of Athens
Diabetic Foot Ulcers (DFU), Lower Extremity Arterial Occlusion
Efficacy and Safety of Cold Atmospheric Plasma Combined With Endovascular Intervention in Patients With Diabetic Foot Ulcers and Lower Extremity Arterial Occlusion
Critical limb ischemia is the end-stage manifestation of peripheral arterial disease (PAD), frequently presenting as ischemic rest pain, ulceration, or gangrene.
- Trial name
- PROSPECT (NCT07073040)
- Testing
- Cold atmospheric plasma (CAP), Successful infrapopliteal angioplasty
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Shenyang Medical College
Radial Artery Occlusion
Comparison of the Systematic Versus the Selective Use of Heparin for the Prevention of Radial Artery Occlusion
Randomized study comparing the systematic use of heparin (standard of care) against an elective use of heparin to prevent radial artery occlusion after a percutaneous catheterization using a dual-artery compression system.
- Trial name
- EASY-Heparin (NCT06981624)
- Testing
- No heparin
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Olivier F. Bertrand
Arterial Occlusion, Cardiovascular Diseases
Comparing Perclose to Statseal in Conjunction With Perclose in Femoral 6 French Arteriotomy Closure
The purpose of this clinical study is to compare how well two different devices for achieving hemostasis perform in patients undergoing transfemoral procedures with 6 French Access.
- Conditions
- Arterial Occlusion, Cardiovascular Diseases, Atherosclerosis, Hematoma
- Trial name
- NCT05468957
- Testing
- Perclose, Statseal
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Lower Limb Ischemia, Peripheral Arterial Disease
The PORTuguese Registry of Supera Supported Femoral-Fopliteal Revascularization (SupPORT Registry)
The SupPORT Registry aims at collecting real-world from Portuguese centers performing femoral-popliteal revascularization with Supera (r) implants. This is a prospective non-randomized non-controlled consecutive registry.
- Conditions
- Lower Limb Ischemia, Peripheral Arterial Disease, Chronic Limb-Threatening Ischemia, Chronic Limb Ischemia
- Trial name
- SupPORT regist (NCT06416644)
- Testing
- Supera Vasculomimetic Stent
- Where
- 15 sites in Portugal
- Volunteers
- 100 people
- Sponsor
- Hospital do Divino Espírito Santo de Ponta Delgada